Results 21 to 30 of about 7,624 (203)

Genotoxicity of Silver Nanoparticles

open access: yesNanomaterials, 2020
Silver nanoparticles (AgNPs) are widely used in diverse sectors such as medicine, food, cosmetics, household items, textiles and electronics. Given the extent of human exposure to AgNPs, information about the toxicological effects of such products is ...
Adriana Rodriguez-Garraus   +3 more
doaj   +1 more source

Lack of genotoxicity of rhubarb (rhizome) in the Ames and micronucleus in vitro tests

open access: yesToxicology Reports, 2022
Hydroxyanthracene derivatives are widely distributed in the plant kingdom, mainly in botanicals such as the Hypericum, Rheum, Rhamnus and Aloe genera.
Gloria Melzi   +4 more
doaj   +1 more source

Antimutagenic effect of resveratrol

open access: yesCzech Journal of Food Sciences, 2005
Evidence exists from population-based and laboratory studies that some phytochemicals have protective effects against tumors or other diseases and reveal antimutagenic activity.
Martina Langová   +4 more
doaj   +1 more source

Cell phone radiation effects on cytogenetic abnormalities of oral mucosal cells

open access: yesBrazilian Oral Research, 2015
The aim of this study was to evaluate the effects of exposure to cell phone electromagnetic radiation on the frequency of micronuclei, broken eggs cells, binucleated cells, and karyorrhexis in epithelial cells of the oral mucosa.
Natália Batista DAROIT   +4 more
doaj   +1 more source

Genotoxicity evaluation of sodium dehydroacetate

open access: yesZhongguo shipin weisheng zazhi, 2020
Objective To study the genotoxicity of sodium dehydroacetate (Na-DHA). Methods Five strains of Salmonella Typhimurium (TA97a, TA98, TA100, TA102 and TA1535) were used with the presence and absence of S9 in bacterial reverse mutation test.
Xue GENG   +8 more
doaj   +1 more source

Study on the genetic damage caused by cadmium sulfide quantum dots in human lymphocytes

open access: yesOpen Life Sciences, 2022
Cadmium sulfide quantum dots (CdS QDs) are being developed for sensors, fluorescent probes, and other platforms and are attracting increasing attention.
Liu Haiping   +7 more
doaj   +1 more source

Genotoxicity Comparison between Morinda citrifolia Fruit and Seed Substances

open access: yesFoods, 2022
This study aimed to evaluate the genotoxic potential of the fruit and seed powder, fruit puree, and aqueous extracts of Morinda citrifolia (Rubiaceae, noni).
Sarah Shin   +3 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal   +3 more
wiley   +1 more source

The Cytogenetic Effects of Crude Ethanol Extracts of Petroselium Crspum Leaves on Bone Marrow In Mice (Mus Musculus) [PDF]

open access: yesEngineering and Technology Journal, 2011
This study aimed to investigate the cytogenetic effects of ethanol extract of Petroselium crispum leaves on somatic cells of albino mice Mus musculus.Four doses (250,500,1000,2000)mgkg were used.Three tests,mitotic index,micronucleus formation and ...
doaj   +1 more source

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