ABSTRACT Background Fanconi anemia (FA) is a rare genetic disorder predisposing patients to oral squamous cell carcinoma (OSCC). Hematopoietic stem cell transplantation (HSCT) corrects bone marrow failure but may increase the risk of malignancies. Exfoliative cytology and the micronucleus (MN) test provide noninvasive assessment of genomic instability.
Bárbara Soldatelli Ballardin +4 more
openalex +2 more sources
Assessment of the Genotoxic and Cytotoxic Effects of Turpentine in Painters
Turpentine is a fluid used mainly as a solvent for thinning oil-based paints, obtained by distilling the resin of coniferous trees. Fine art painters use turpentine on a daily basis.
Sara Kević Dešić +2 more
doaj +1 more source
Background. Every year, thousands of donors are exposed to granulocyte-colony stimulating factor (G-CSF) for stem cell mobilization in hematopoietic stem cell transplantations (HSCT).
Hasan Fatih Çakmaklı +5 more
doaj +1 more source
Micronucleus level in exfoliated buccal mucosa cells of cancer patients [PDF]
Micronucleus levels in exfoliated buccal mucosa cells of patients with primary breast, lung, cervix uteri cancer, and patients with Hodgkin's disease were studied (n=59).
Nersesyan Armen K. +3 more
doaj +1 more source
Evaluation of Fish Micronucleus Results in Turkish Ecogenotoxicological Studies
In recent years, ecotoxicological studies have been conducted around the world, especially in aquatic ecosystems. It is noteworthy that genotoxicity tests have been frequently used in the biomonitoring of pollution.
Gülşen GÖNEY , Cengiz GAZELOĞLU
doaj +1 more source
Biomonitoring of the genotoxic potential of aqueous extracts of soils and bottom ash resulting from municipal solid waste incineration, using the comet and micronucleus tests on amphibian (Xenopus laevis) larvae and bacterial assays (MutatoxR and Ames tests) [PDF]
The management of contaminated soils and wastes is a matter of considerable human concern. The present study evaluates the genotoxic potential of aqueous extracts of two soils (leachates) and of bottom ash resulting from municipal solid waste ...
Gauthier, Laury +11 more
core +1 more source
The increased use of biostimulants in conventional agriculture and organic farming requires the implementation of rapid tests to determine their effectiveness in enhancing plant growth and protection against abiotic stresses.
Perrine Klein +5 more
doaj +1 more source
Salivary ki-67 and micronucleus assay as potential biomarker of OSCC in betel nut chewers
Introduction: Oral cancer is often associated with various factors, such as betel nut consumption, which usually causes specific premalignant lesions. The most common oral cancer is oral squamous cell carcinoma (OSCC) which has a low 5-year survivor rate
Maulina Triani +4 more
doaj +1 more source
Scientific Opinion on the safety evaluation of the substance, 1,3-bis(isocyanatomethyl)benzene, CAS No. 3634-83-1 for use in food contact materials [PDF]
<p>This scientific opinion of EFSA deals with the risk assessment of the monomer 1,3-bis(isocyanatomethyl) benzene, CAS No. 3634-83-1, FCM Substance No 988.
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj +1 more source
Preclinical and Toxicology Studies of LPM7100328, a Novel Oral GnRH Antagonist. [PDF]
ABSTRACT LPM7100328 is a novel oral GnRH antagonist being developed for the prevention of premature luteinizing hormone (LH) surges in women undergoing controlled ovarian stimulation. The studies presented herein reported assessment of safety in favor of human clinical trials.
Wang Y +9 more
europepmc +2 more sources

