Clastogenicity of Piper cubeba (Piperaceae) seed extract in an in vivo mammalian cell system
Genetics and Molecular Biology, 2007 The plant Piper cubeba is widely distributed in tropical and subtropical regions and is used medically for various purposes but has not yet been evaluated for genotoxicity.
Adriana Pereira Freire Junqueira +3 more
doaj +1 more source
, 2021 About adequacy of the standardised in vitro mammalian cell Micronucleus (MN) test for nanomaterials genotoxicity testing.info:eu-repo/semantics ...
Fernández-Bertólez, Natalia +8 more
core
Cytogenotoxic and Molecular Assessment of Pyrethrins on Non‐Target Allium cepa Roots
Environmental Toxicology, EarlyView.ABSTRACT The pyrethrins, which form a part of naturally occurring insecticidal chemicals derived from chrysanthemum flowers, not only provide rapid knockdown of a broad spectrum of insect pests but are also widely used in integrated pest management due to a generally favorable safety profile, largely attributed to low mammalian toxicity.
Yudum Yeltekin Uğur +2 more
wiley +1 more source
Healthy Participant Versus Patient Selection for Clinical Pharmacology Studies in Small-Molecule Oncology Drug Development. [PDF]
Clin Transl SciClinical and Translational Science, Volume 19, Issue 11, November 2026.
Gupta P, Hu Z, Zhu L, Hamuro L.
europepmc +2 more sources
Trace Levels of Triclosan May Affect Root Growth and Morphology in Cultivated Plants
Environmental Toxicology, EarlyView.ABSTRACT Triclosan (TCS) is a micropollutant frequently detected in biosolids applied to agricultural soils. In soil solution—where it is potentially bioavailable to roots—it occurs at residual concentrations (ng L−1). Nevertheless, the ecotoxicological implications of TCS exposure in agricultural crops at these concentrations are still not fully ...
Lizandra de Souza Ratuchinski +10 more
wiley +1 more source
Genotoxicity evaluation of sodium dehydroacetate
Zhongguo shipin weisheng zazhi, 2020 Objective To study the genotoxicity of sodium dehydroacetate (Na-DHA). Methods Five strains of Salmonella Typhimurium (TA97a, TA98, TA100, TA102 and TA1535) were used with the presence and absence of S9 in bacterial reverse mutation test.
Xue GENG +8 more
doaj +1 more source
The Micronucleus Test as an in Vivo Cytogenetic Method
Environmental Health Perspectives, 1973 Methods are currently being explored which would permit the application of cytogenetic procedures such as metaphase and anaphase analyses to in vivo mammalian systems in order that due consideration may be given to metabolic activation or detoxification reactions which might affect the mutagenic or clastogenic (chromosome breaking) potential of ...
openaire +2 more sources
Micronucleus Incidence and Their Chromosomal Origin Related to Therapy in Acute Lymphoblastic Leukemia (ALL) Patients: Detection by Micronucleus and FISH Techniques [PDF]
, 2001 Micronucleus assay and dual color-fluorescence in situ hybridization (DC-FISH), using centromere-specific and whole chromosome-specific painting probes, are considered a useful screening test to determine the incidence of micronucleus, their origin and ...
Çalışkan, Ümran +3 more
core +1 more source
Automated urine analysis of atypical urothelial cells for urothelial carcinoma: a prospective study
BJU International, EarlyView.Objectives To prospectively evaluate the diagnostic value of atypical urothelial cells (Atyp.C), an automatically determined quantitative parameter of the Sysmex UF‐5000 urine particle analyser (Sysmex Corp., Kobe, Japan), as a non‐invasive biomarker for urothelial carcinoma (UC). Early diagnosis of UC remains challenging despite advances in diagnostic
Maximilian Reimann +8 more
wiley +1 more source