Micronucleus Test of Picrorrhiza Rhizoma Aqueous Extract in Bone Marrow Cells of Male ICR Mice
In this research, the genotoxic effect of Picrorrhiza Rhizoma (PR) aqueous extract was evaluated using the mouse micronucleus test. PR extract was administered once a day for 2 continuous days by oral gavage to male ICR mice at doses of 2000, 1000 and ...
In-Kwon Chung, Woo-hyun Cheon, S. Ku
semanticscholar +1 more source
In vivo and in vitro genotoxicity of N-nitrosopyrrolidine following UVA irradiation
N-nitrosopyrrolidine (NPYR) is a volatile nitrosamine that is thought to be a human carcinogen. It is found in air, wastewater, food, and feed. Photo-activation of NPYR can occur as it drifts through the environment.
Yusuke Hanaki, Sakae Arimoto-Kobayashi
doaj +1 more source
Characterization and genotoxicity evaluation of effluent from a pharmacy industry
The pharmaceutical, textile and food industry bear much of the responsibility for environmental pollution. In order to appropriately treat and mitigate the effects of pharmaceutical effluent, it is necessary to study it in order to determine its physical
Hélio Mendes de Oliveira Júnior +5 more
doaj +1 more source
The aflatoxin B1-fumonisin B1 toxicity in BRL-3A hepatocytes is associated to induction of cytochrome P450 activity and arachidonic acid metabolism [PDF]
Human oral exposure to aflatoxin B1 (AFB1) and fumonisin B1 (FB1) is associated with increased hepatocellular carcinoma. Although evidence suggested interactive AFB1–FB1 hepatotoxicity, the underlying mechanisms remain mostly unidentified.
Arias, Silvina Lorena +5 more
core +1 more source
Micronucleus test in erythrocytes of Barbus plebejus (Teleostei, Pisces) from two natural environments: A bioassay for the in situ detection of mutagens in freshwater [PDF]
Erythrocyte micronucleus frequencies in wild fish from two riverine environments and in fish reproduced and reared under controlled conditions (control group) were compared, with the aim to evaluate the suitability of the MN test for the in situ ...
Ciccotti, E, Minissi, S, Rizzoni, M
core +1 more source
Micronucleus Assay for Evaluation of Genotoxicity in Potentially Malignant and Malignant Disorders
Oral cancer is a common malignancy, ranking first among all cancers in Western and Asian countries. It is preceded by some benign lesions or conditions, which are termed precancerous.
Parvathi Devi +3 more
doaj +1 more source
Assessment of the potential in vivo ecotoxicity of Double-Walled Carbon Nanotubes (DWNTs) in water, using the amphibian Ambystoma mexicanum [PDF]
Because of their specific properties (mechanical, electrical, etc), carbon nanotubes (CNTs) are being assessed for inclusion in many manufactured products.
Borm PJA +37 more
core +3 more sources
Peningkatan Jumlah Mikronukleus pada Mukosa Gingiva Kelinci Setelah Paparan Radiografi Panoramik
Mikronukleus merupakan salah satu tanda awal terjadinya kerusakan DNA yang ditemukan pada mukosa gingiva manusia setelah paparan radiografi dental panoramik.
Rurie Ratna Shantiningsih +3 more
doaj +1 more source
In vitro approach to the study of chronic exposure to low doses of x-rays [PDF]
El presente trabajo fue realizado con el fin de estudiar el efecto de dosis bajas y repetidas de radiación sobre dos líneas celulares de la misma especie. Se desarrolló un modelo in vitro para evitar la influencia de los factores de confusión que afectan
Peral Garcia, Pilar +2 more
core +1 more source
Herbal Remedies for Combating Irradiation: a Green Antiirradiation Approach [PDF]
Plants play important roles in human life not only as suppliers of oxygen but also as a fundamental resource to sustain the human race on this earthly plane.
Choong, Y. S. +8 more
core +1 more source

