Results 81 to 90 of about 6,895,334 (230)
Chromosomal and immune dysregulation underlying granular mitosis in glioblastoma
Brain Pathology, EarlyView.Granular mitosis (GM) morphology is linked to PI3K/PTEN pathway alterations, chromosomal disorganization, and impaired innate immunity. Cells exhibiting GM morphology are associated with localized immune responses within their immediate spatial microenvironment.
Rachel Barboza +8 more
wiley +1 more source
Genetics and Molecular Biology, 2011 The aim of this study was to assess the use of pesticides on farms located in the Lambedor River watershed in Guatambu, State of Santa Catarina, as well as to determine, by micronucleus testing, the risk of genotoxic impact.
Jaqueli Salvagni +2 more
doaj
Clinical Oral Implants Research, EarlyView.ABSTRACT Background Postmenopausal osteoporosis associated with cafeteria diet and bisphosphonate therapy may impair peri‐implant bone repair. Therefore, strategies to enhance osseointegration are needed. Aim This study investigated whether teriparatide‐coated implant surfaces enhance osseointegration in a rodent model of estrogen deficiency (OVX) and ...
Ana Cláudia Ervolino da Silva +9 more
wiley +1 more source
International Aquatic Research, 2018 The use of organophosphate pesticides (OPs) in agricultural practices in India has gained popularity due to their broad spectrum, low cost and high potency.
Avelyno H. D’Costa +3 more
doaj +1 more source
Plant Breeding, EarlyView.ABSTRACT The combination of polyploidy, apomixis and the formation of aneuploid and interploid hybrids makes the genus Urochloa an interesting system for investigating meiotic stability and genome behaviour in grasses. In this study, routine meiotic analysis and genomic in situ hybridization (GISH) were used to (i) evaluate meiosis in three hybrids of ...
Isabella Campos Moraes +3 more
wiley +1 more source
Chemoprotective Effects of Broccoli Juice Treated with High Pressure
Czech Journal of Food Sciences, 2006 We investigated chemoprotective effects of broccoli juice, treated with high pressure method, using 500 MPa for a period of 10 minutes. By the use of this method, the conservation of nutritionally important substances occurs (for example vitamins ...
Lucie Mandelová, Jiří Totušek
doaj +1 more source
Journal of Applied Toxicology, Volume 46, Issue 12, Page 4396-4408, December 2026.ABSTRACT Children, as a particularly vulnerable group, are more susceptible to these mutagens due to their developing immune systems, higher physiological vulnerability, and increased exposure through behaviors like outdoor play and hand‐to‐mouth activities. This review aims to investigate the relationship between these environmental exposures, genetic
Thiago Guedes Pinto +7 more
wiley +1 more source
Testing for Genotoxicity of Indigo Naturalis Assessed by Micronucleus Test
Natural Product Communications, 2010 In the field of cosmetic dyes, used for coloring the hair and skin, there is a clear tendency to replace the widely used synthetic dyes by natural colorants, such as henna and mixtures of henna with indigo.
Luca Dominici +4 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, Volume 20, Issue 11, Page 2820-2838, November 2026.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source