Genotoxicity evaluation of So-ochim-tang-gamibang (SOCG), a herbal medicine
BMC Complementary and Alternative Medicine, 2018 Background So-ochim-tang-gamibang (SOCG) is a traditional Korean medicine frequently used for depression in the clinical field. In this study, we evaluated the potential genotoxicity of SOCG using three standard batteries of tests as part of a safety ...
Mi Young Lee +5 more
doaj +1 more source
Development of a micronucleus test using the EpiAirway™ organotypic human airway model. [PDF]
Genes Environ, 2023 Munakata S +5 more
europepmc +1 more source
A Family of Developmentally Excised DNA Elements in \u3cem\u3eTetrahymena\u3c/em\u3e is under Selective Pressure to Maintain an Open Reading Frame Encoding an Integrase-Like Protein [PDF]
, 2000 Tlr1 is a member of a family of ~20-30 DNA elements that undergo developmentally regulated excision during formation of the macronucleus in the ciliated protozoan Tetrahymena.
Gershan, Jill A., Karrer, Kathleen M.
core +1 more source
, 2018 Background: The chromatin remodelers of the SWI/SNF family are critical transcriptional regulators. Recognition of lysine acetylation through a bromodomain (BRD) component is key to SWI/SNF function; in most eukaryotes, this function is attributed to ...
Burtch, Alyson +9 more
core +1 more source
Reply to the opinion paper: is micronucleus test a suitable method for monitoring oral mucosa exposed to dental bleachings in smokers? [PDF]
Arch Toxicol, 2023 Silva RR +7 more
europepmc +1 more source
Site-Specific Methylation of Adenine in the Nuclear Genome of a Eucaryote, \u3cem\u3eTetrahymena thermophila\u3c/em\u3e [PDF]
, 1986 DNA in the polyploid macronucleus of the ciliated protozoan Tetrahymena thermophila contains the modified base N6-methyladenine. We identified two GATC sites which are methylated in most or all of the 45 copies of the macronuclear genome.
Findly, R. Craig +2 more
core +1 more source
Comprehensive interpretation of in vitro micronucleus test results for 292 chemicals: from hazard identification to risk assessment application. [PDF]
Arch Toxicol, 2022 Kuo B +8 more
europepmc +1 more source
Evaluation of the Genotoxicity of Bangpungtongsung-San, a Traditional Herbal Prescription [PDF]
Pakistan Veterinary Journal, 2014 Bangpungtongsung-san (BPS) is a traditional Korean herbal formula used as an anti-inflammatory, antipyretic, antiobesity, and choleretic agent, which consists of 18 herbs.
In-Sik Shin +6 more
doaj
Evaluation of a 4-day repeated-dose micronucleus test in rat glandular stomach and colon using aneugens and non-genotoxic non-carcinogens. [PDF]
Genes Environ, 2022 Okada E, Fujiishi Y, Narumi K, Ohyama W.
europepmc +1 more source
Validation of the micronucleus-centromere assay for biological dosimetry
Genetics and Molecular Biology, 2000 The micronucleus assay is frequently used for purposes of biological dosimetry. Due to high interindividual variability in the spontaneous frequency of micronuclei, its sensitivity in the low dose region is poor.
Wojcik A. +6 more
doaj