Results 101 to 110 of about 6,895,334 (230)

PEGylated Chrysin: In Vitro Biological Activity and Mechanistic Insights in HepG2 Cells

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.
PEGylated chrysin exhibited antiproliferative effects in HepG2 cells, inducing apoptosis, membrane damage, genotoxicity, and wound closure. Compared to paclitaxel, it caused lower ROS production and overall cytotoxicity, while efficiently accumulating in the cytoplasm, supporting its potential as a liver cancer therapeutic candidate. ABSTRACT PEGylated
Fátima Belén Gasser, Julia Oggero, María Sol Renna, María Florencia Beltramino, Candela Simonetto, Lucía Dominguez, Hugo Héctor Ortega, Santiago Eduardo Vaillard, Victoria Anahí Vaillard, María Eugenia Baravalle   +9 more
wiley   +1 more source

Protein Lactylation in Cancer: From Mechanisms to Therapy

MedComm, Volume 7, Issue 11, November 2026.
Increased glycolysis and lactate accumulation promote histone and nonhistone protein lactylation, linking tumor metabolic reprogramming to treatment adaptation. Lactylation enhances DNA repair, suppresses antitumor immunity, strengthens antioxidant defenses, and facilitates cell‐cycle checkpoint escape, collectively promoting resistance to chemotherapy,
Wentian Huang, Ping Hu, Shun Wang, Xide Zhang, Ziran Ye, Shengqiang Chen, Fu Gao, Yuanyuan Chen, Yanyong Yang   +8 more
wiley   +1 more source

Peningkatan Jumlah Mikronukleus pada Mukosa Gingiva Kelinci Setelah Paparan Radiografi Panoramik

Majalah Kedokteran Gigi Indonesia, 2013
Mikronukleus merupakan salah satu tanda awal terjadinya kerusakan DNA yang ditemukan pada mukosa gingiva manusia setelah paparan radiografi dental panoramik.
Rurie Ratna Shantiningsih, Suwaldi Suwaldi, Indwiani Astuti, Munakhir Mudjosemedi   +3 more
doaj   +1 more source

micronucleus test

Citation: 'micronucleus test' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10960 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Genotoxicity evaluation of alpha-linolenic acid-diacylglycerol oil

Toxicology Reports, 2016
The alpha-linolenic acid (ALA)-diacylglycerol (DAG) oil is an edible oil enriched with DAG (>80%) and ALA (>50%). Although DAG oil, which mainly consists of oleic and linoleic acids has no genotoxic concerns, the fatty acid composition could affect the ...
Hiroshi Honda, Yurika Fujita, Aya Hayashi, Naohiro Ikeda, Yuichi Ito, Osamu Morita   +5 more
doaj   +1 more source

In Vivo Genotoxicity Evaluation of a No-Pain Pharmacopuncture Extract Using the Micronucleus Test. [PDF]

J Pharmacopuncture, 2023
Hwang JH, Jung C.
europepmc   +1 more source

Evaluation of The Genotoxicity of Three Food Additives using CHO-K1 Cells under in vitro Micronucleus Flow Cytometry Assay

, 2017
Exposure of genotoxic substances come from various sources such as food additives. The aim of this study is to evaluate the genotoxicity of food additives in CHO-K1 cells by micronucleus test flow cytometry.
Herwandhani Putri, Ediati Sasmito, Dhania Novitasari, Beni Lestari, Edy Meiyanto, Sari Haryanti   +5 more
core   +1 more source

Pharmacological and Therapeutic Potential of Garlic (Allium sativum): Integrating Phytochemistry, Molecular Mechanisms, and Clinical and Preclinical Evidence

ChemistryOpen, Volume 15, Issue 11, November 2026.
Garlic bioactive compounds, including organosulfur compounds (allicin, DADS, DATS, and SAC), phenolic compounds, and quercetin, regulate the Nrf2/HO‐1, NF‐κB, PI3K/Akt, and AMPK/eNOS signaling pathways. These actions enhance antioxidant defenses, suppress inflammation, improve metabolic and cardiovascular function, and contribute to reduced blood ...
Gudisa Bereda
wiley   +1 more source

Test Submission

, 2021
This is a sample submission generated by Vireo to test the repository deposit features.Test ...
Submitter, Test
core  

Mitigating Photoinduced Reactive Oxygen Species From TiO2 and ZnO UV Filters: Materials Design and Evaluation

ChemistrySelect, Volume 11, Issue 42, 10 November 2026.
Photoinduced reactive oxygen species (ROS) from titanium dioxide (TiO2) and zinc oxide (ZnO) ultraviolet (UV) filters can be controlled through particle engineering, surface passivation, and formulation design. This Review links material structure and interfacial chemistry with ROS evaluation and proposes a tiered framework from photoreactivity ...
Chenge Wang
wiley   +1 more source