Results 121 to 130 of about 6,597,635 (260)
Validation of the micronucleus-centromere assay for biological dosimetry
The micronucleus assay is frequently used for purposes of biological dosimetry. Due to high interindividual variability in the spontaneous frequency of micronuclei, its sensitivity in the low dose region is poor.
Wojcik A. +6 more
doaj
Evaluation of the Genotoxicity of Bangpungtongsung-San, a Traditional Herbal Prescription [PDF]
Bangpungtongsung-san (BPS) is a traditional Korean herbal formula used as an anti-inflammatory, antipyretic, antiobesity, and choleretic agent, which consists of 18 herbs.
In-Sik Shin +6 more
doaj
In Vivo Genotoxicity Evaluation of a Stilbene Extract Prior to Its Use as a Natural Additive: A Combination of the Micronucleus Test and the Comet Assay. [PDF]
Medrano-Padial C +7 more
europepmc +1 more source
Cinnamaldehyde derived from Cinnamomum species exerts multitarget anticancer effects by promoting oxidative stress, mitochondrial dysfunction, apoptosis, cell‐cycle arrest, autophagy, and epigenetic changes, and by suppressing mitogen‐activated protein kinase (MAPK), phosphoinositide 3‐kinase/protein kinase B/mechanistic target of rapamycin (PI3K/Akt ...
Gervason Moriasi +6 more
wiley +1 more source
The micronucleus test: A method used in mutagenicity testing
Micronucleus is a c7,16111ss1uc rontd bodl' v'hich contains chronatin nass (DNA). Micronuclei arise when replicating cell populatiotts are subiected to chrontosotttal breaknge by clastogens (agents causing chrontosonal breakrtge) or to chronrosotne loss by ntitotic spindle d1'sfunctiotr.
openaire +2 more sources
Chromosomal instability is a hallmark of cancer, but minimally invasive ways to detect systemic DNA damage and cancer risk remain limited. Here, using patient blood samples, the authors investigated lymphocyte micronuclei (MN) frequency as a potential marker of DNA damage across the progression from gastroesophageal reflux disease to Barrett's ...
Kathryn Munn +13 more
wiley +1 more source
Analytical method cross validation by HPLC for identification of five markers and quantification of one marker in SynacinnTM formulations and its in vivo bone marrow micronucleus test data. [PDF]
Zainol SN +10 more
europepmc +1 more source
Vanillic acid, a dietary phenolic, dose‐dependently protects Drosophila melanogaster from acrylamide‐induced oxidative damage, DNA strand breaks, and developmental toxicity by modulating CncC/Keap1 redox signaling—establishing vanillic acid as a candidate natural protective agent against a major environmental contaminant.
Fahriye Zemheri‐Navruz +2 more
wiley +1 more source
Azo dye Acid Red 119 exerts marked DNA damage, oxidative stress, antioxidant enzymatic, and histopathological alterations in the blood and gills of freshwater fish Channa punctata, underscoring the urgent need for stricter effluent regulation and sustainable treatment strategies in textile industries.
Harpal Kaur +3 more
wiley +1 more source

