Results 21 to 30 of about 12,961 (162)

Maximum tolerated doses and erythropoiesis effects in the mouse bone marrow by 79 pesticides’ technical materials assessed with the micronucleus assay

Toxicology Reports, 2019
Effects of technical materials of pesticide active ingredients, belonging to various chemical classes, on erythropoiesis in mouse bone marrow were studied as part of the research on the pesticide mutagenic activity in micronucleus test.
Nataliya Ilyushina, Marina Goumenou, Polychronis D. Stivaktakis, Alexander I. Vardavas, Gleb Masaltsev, Nataliya Averianova, Olga Dmitricheva, Yulia Revazova, Aristidis M. Tsatsakis, Valerii Rakitskii   +9 more
doaj   +1 more source

Mutagenicity induced by the hydroalcoholic extract of the medicinal plant Plathymenia reticulata Benth

Journal of Venomous Animals and Toxins including Tropical Diseases, 2011
Plathymenia reticulata Benth has an anti-inflammatory effect and is capable of neutralizing the neuromuscular blockade induced by Bothrops jararacussu or Crotalus durissus terrificus venoms, probably by precipitating venom proteins (an effect caused by ...
A Della Torre, LBL Albuquerque, NM Farrapo, Y Oshima-Franco, MG Santos, RVS Tavares, ACD Rodas, CA Dal Belo, CRP Cardoso, EA Varanda, FC Groppo, PS Lopes   +11 more
doaj   +1 more source

Study of Genotoxicity, Activities on Caspase 8 and on the Stabilization of the Topoisomerase Complex of Isoeleutherin and Analogues

Molecules, 2023
This study evaluated the genotoxicity of Ethanol Extract (EEEp), Dichloromethane Fraction (FDCMEp) and isoeleutherin isolated from Eleutherine plicata, using the micronucleus test and the impact of structural alterations on toxicity and molecular docking
Kelly Cristina Oliveira de Albuquerque, Natasha Costa da Rocha Galucio, Gleison Gonçalves Ferreira, Ana Carolina Sousa Quaresma, Valdicley Vieira Vale, Marcelo de Oliveira Bahia, Rommel Mario Rodriguez Burbano, Fábio Alberto de Molfetta, Sandro Percario, Maria Fâni Dolabela   +9 more
doaj   +1 more source

Evaluation of the edible safety of Amaranthus caudatus seeds based on cellular and toxicological experiments [PDF]

Zhongguo niangzao
A toxicological evaluation for edible safety of Amaranthus caudatus seeds was conducted. In the acute oral toxicity test, SPF mice was administered a one-time gavage at a dose of 10 000 mg/kg.
A Ruhan, LU Bingyun, HE Mengchao, ZHONG Heng, HAN Xinglin, LUO Ruiqi, WANG Deliang
doaj   +1 more source

Evaluation of the novel liver micronucleus assay using formalin-fixed tissues

Genes and Environment, 2019
Background The repeated-dose liver micronucleus (RDLMN) assay is an effective and important in vivo test for detecting genotoxic compounds, particularly for those that require metabolic activation to show genotoxicity.
Shuichi Hamada, Miyuki Shigano, Satoru Kawakami, Maya Ueda, Hajime Sui, Katsuya Yamada, Soichiro Hagio, Ayaka Momonami, Akihisa Maeda, Yukari Terashima, Wakako Ohyama, Takeshi Morita, Makoto Hayashi   +12 more
doaj   +1 more source

GENOTOXIC AND PROBABLE MUTAGENIC EFFECTS OF SOME PESTICIDES ON MICE BONE MARROW CELLS [PDF]

Journal of Plant Protection and Pathology, 2010
Lambda-cyhalothrin, Profenofos and Chlorpyrifos are a broad-spectrum pesticides extensively used to control pests for agricultural and household purposes.
F. Hosam Eldeen, M. Kady, A. Saleh, Salwa Negm, H. El-Bendary   +4 more
doaj   +1 more source

MICRONUCLEUS TEST IN MOST RECENT ICHTHIOLOGY RESEARCH [PDF]

Croatian Journal of Fisheries, 2005
The purpose of this paper was to give an insight into the most recent ichthiology research in which Micronucleus test is used. This test has been used for some time now as a tool for determining DNA damage in model–organism. Scientists have been using it
Vesna Mijat
doaj  

Evaluation of genotoxicity through micronuclei test in workers of car and battery repair garages

Genetics and Molecular Biology, 2002
In this study, the micronuclei test (MNT) was applied in exfoliated cells of buccal mucosa, in order to evaluate the genotoxic risk associated with occupational exposure of mechanics, storage battery renovation workers, and car painters.
M.G. Martino-Roth, J. Viégas, M. Amaral, L. Oliveira, F.L.S. Ferreira, B. Erdtmann   +5 more
doaj   +1 more source

Guidance on aneugenicity assessment

EFSA Journal, 2021
The EFSA Scientific Committee was asked to provide guidance on the most appropriate in vivo tests to follow up on positive in vitro results for aneugenicity, and on the approach to risk assessment for substances that are aneugenic but not clastogenic nor
EFSA Scientific Committee (SC), Simon John More, Vasileios Bampidis, Claude Bragard, Thorhallur Ingi Halldorsson, Antonio F Hernández‐Jerez, Susanne Hougaard Bennekou, Kostas Koutsoumanis, Claude Lambré, Kyriaki Machera, Hanspeter Naegeli, Søren Saxmose Nielsen, Josef Schlatter, Dieter Schrenk, Dominique Turck, Maged Younes, Gabriele Aquilina, Margherita Bignami, Claudia Bolognesi, Riccardo Crebelli, Rainer Gürtler, Francesca Marcon, Elsa Nielsen, Christiane Vleminckx, Maria Carfì, Carla Martino, Daniela Maurici, Juan Parra Morte, Annamaria Rossi, Diane Benford   +29 more
doaj   +1 more source

Bisphenol-A Release and Genotoxicity Differences of Three Branded Adhesives Materials

Journal of Dentistry Indonesia, 2015
Objectives: The objective of the study are to determine BPA release and genotoxicity differences between three adhesives, and to determine the relationship between BPA release and genotoxicity.
Lydia Winarta, Rahmi Amtha, Boedi O. Roeslan, Himawan Halim   +3 more
doaj   +1 more source