Results 21 to 30 of about 44,814 (262)

The Acute Immune Responses of the Common Carp Cyprinus carpio to PLGA Microparticles—The Interactions of a Teleost Fish with a Foreign Material

Biomolecules, 2022
Poly lactic-co-glycolic acid (PLGA) particles safely and effectively deliver pharmaceutical ingredients, with many applications approved for clinical use in humans.
Ruth Montero, Justin Tze Ho Chan, Bernd Köllner, Roman Kuchta, Jakub Vysloužil, Peter Podhorec, Astrid Sibylle Holzer, Tomáš Korytář   +7 more
doaj   +1 more source

Preparation of Spray-Dried Soy Isoflavone-Loaded Gelatin Microspheres for Enhancement of Dissolution: Formulation, Characterization and in Vitro Evaluation

Pharmaceutics, 2014
The most bioactive soy isoflavones (SI), daidzein (DAI) and genistein (GEN) have poor water solubility, which reduces their bioavailability and health benefits and limits their use in industry. The goal of this study was to develop and characterize a new
Gean Pier Panizzon, Fernanda Giacomini Bueno, Tânia Ueda-Nakamura, Celso Vataru Nakamura, Benedito Prado Dias Filho   +4 more
doaj   +1 more source

Effect of the TiO₂ Colloidal Size Distribution on the Degradation of Methylene Blue

Nanomaterials, 2023
TiO2 is the most commonly used photocatalyst in water treatment. The particle size of TiO2 is an important factor that significantly influences its activity during photocatalytic degradation.
So-Yul Kim, Tae-Geol Lee, Seon-Ae Hwangbo, Jong-Ryul Jeong   +3 more
doaj   +1 more source

On the Trail of Microparticles [PDF]

Circulation Research, 2009
Stimulation of a variety of cell types leads to the release of submicron vesicles that bud off from the plasma membrane. These so-called microparticles (MPs) or microvesicles are defined by their small size (0.1 to 1 μm) and the presence of surface antigens from the parental cells.1,2 MPs contribute to a variety of physiological and pathological ...
openaire   +2 more sources

Design and synthesis of multivalent α-1,2-trimannose-linked bioerodible microparticles for applications in immune response studies of Leishmania major infection

Beilstein Journal of Organic Chemistry, 2019
Leishmaniasis, a neglected tropical disease, currently infects approximately 12 million people worldwide with 1 to 2 million new cases each year in predominately underdeveloped countries. The treatment of the disease is severely underdeveloped due to the
Chelsea L. Rintelmann, Tara Grinnage-Pulley, Kathleen Ross, Daniel E. K. Kabotso, Angela Toepp, Anne Cowell, Christine Petersen, Balaji Narasimhan, Nicola Pohl   +8 more
doaj   +1 more source

Driving Rotational Circulation in a Microfluidic Chamber Using Dual Focused Surface-Acoustic-Wave Beams

Micromachines
In this paper, enhanced rotational circulation in a circular microfluidic chamber driven by dual focused surface-acoustic-wave (SAW) beams is presented. To characterize the resonant frequency and focusing effect, we simulate the focused SAW field excited
Jin-Chen Hsu, Kai-Li Liao
doaj   +1 more source

The Effect of the Layered Internal Structure of Fibrous Beds on the Hydrodynamic Diffusive Behavior of Microparticles

Micromachines, 2021
To separate and collect microparticles such as cells, the behavior of particles in fibrous filters was investigated. It is essential to understand, in detail, the motion of particles in microscale flows, because Re is often small, and particles exhibit ...
Ryoko Otomo, Ryosuke Kira
doaj   +1 more source

Probing Critical Physical Properties of Lactose-Polyethylene Glycol Microparticles in Pulmonary Delivery of Chitosan Nanoparticles

Pharmaceutics, 2021
Pulmonary delivery of chitosan nanoparticles is met with nanoparticle agglomeration and exhalation. Admixing lactose-based microparticles (surface area-weighted diameter~5 μm) with nanoparticles mutually reduces particle agglomeration through surface ...
Nasser Alhajj, Idanawati Naharudin, Paolo Colombo, Eride Quarta, Tin Wui Wong   +4 more
doaj   +1 more source

Microparticles in Cancer [PDF]

Seminars in Thrombosis and Hemostasis, 2010
Microparticles (MP) are vesicular structures released from cells upon activation, malignant transformation, stress, or death. MP may be derived from the plasma membrane (shed microvesicles), produced by endosomal pathway (exosomes), or arise from membrane blebs of apoptotic cells. The terms microparticles or microvesicles (MV) are often used as general
openaire   +3 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source