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An Avirulent Micropterus salmoides Rhabdovirus Vaccine Candidate Protects Chinese Perch Against Rhabdovirus Infection

Fish and Shellfish Immunology, 2018
In order to develop live vaccine against Siniperca chuatsi rhabdovirus (SCRV) disease, an avirulent virus strain, designed as Micropterus salmoides rhabdovirus Sanshui (MSRV-SS), was selected from six fish rhabdovirus isolates (SCRV-QY、SCRV-SS、SCRV-GM、CMRV-FS、OMBRV-JM、MSRV-SS) by fish challenge assay.
Xiaozhe Fu, Hongru Liang, Zhibin Huang
exaly   +3 more sources

Infection dynamic of Micropterus salmoides rhabdovirus and response analysis of largemouth bass after immersion infection

Fish & Shellfish Immunology, 2023
Largemouth bass (Micropterus salmoides) is an important economic freshwater aquaculture fish originating from North America. However, the frequent outbreaks of Micropterus salmoides rhabdovirus (MSRV) have seriously limited the healthy development of Micropterus salmoides farming industry.
Shunfa, Yi   +10 more
openaire   +2 more sources

The recombinant subunit vaccine encapsulated by alginate‐chitosan microsphere enhances the immune effect against Micropterus salmoides rhabdovirus

Journal of Fish Diseases, 2022
AbstractThe disease caused by Micropterus salmoides rhabdovirus (MSRV) has brought substantial economic losses to the largemouth bass aquaculture industry in China. Vaccination was considered as a potential way to prevent and control this disease. As a kind of sustained and controlled release system, alginate and chitosan microspheres (SA‐CS) are ...
Fei‐Fan Xu   +5 more
openaire   +2 more sources

Galla Chinensis as an antiviral agent: Targeting Micropterus salmoides rhabdovirus infection

Fish & Shellfish Immunology
Being a major pathogen affecting the health of largemouth bass (Micropterus salmoides) aquaculture, Micropterus salmoides rhabdovirus (MSRV) causes significant economic losses. Galla chinensis, a traditional Chinese medicinal herb, possesses diverse biological activities, including antiviral properties.
Jieying, Yu   +14 more
openaire   +2 more sources

Rapid visual detection of Micropterus salmoides rhabdovirus using recombinase polymerase amplification combined with lateral flow dipsticks

Journal of Fish Diseases, 2022
Abstract Largemouth bass ( Micropterus salmoides ) is an important freshwater‐cultured species in China. Recently, a lethal and epidemic disease caused by Micropterus salmoides rhabdovirus (MSRV) results in huge economic losses to the ...
Zizhao Feng   +7 more
openaire   +2 more sources

Quinoline, with the active site of 8‐hydroxyl, efficiently inhibits Micropterus salmoides rhabdovirus (MSRV) infection in vitro and in vivo

Journal of Fish Diseases, 2022
AbstractMicropterus salmoides rhabdovirus (MSRV) is an significant pathogen that causes high mortality and related economic losses in bass aquaculture. There is no effective or approved therapy to date. In this study, we evaluated the anti‐MSRV effects of 22 quinoline derivatives in grass carp ovary (GCO) cells.
Bo‐Yang Li   +8 more
openaire   +2 more sources

Epigallocatechin gallate (EGCG) inhibits Micropterus salmoides rhabdovirus replication via suppressing viral attachment and infectivity

Fish & Shellfish Immunology
Micropterus salmoides rhabdovirus (MSRV) remains an economically important pathogen in the global largemouth bass industry, effective drugs to control the virus are still lacking. Epigallocatechin gallate (EGCG), the most abundant and bioactive catechin in green tea, possesses multiple biological activities, including widespread antiviral effects ...
Yuhang, Wang   +6 more
openaire   +2 more sources

Carbon nanotubes-loaded subunit vaccine can increase protective immunity against rhabdovirus infections of largemouth bass (Micropterus Salmoides)

Fish & Shellfish Immunology, 2020
Micropterus Salmoides rhabdovirus (MSRV), as a common aquatic animal virus, can cause lethal and epidemic diseases in the cultivation of largemouth bass. In this study, we reported a kind of immersion single-walled carbon nanotubes-loaded subunit vaccine which composited by glycoprotein (G) of MSRV, and evaluated its protective effect on largemouth ...
Zi-Rao, Guo   +6 more
openaire   +2 more sources

Micropterus salmoides rhabdovirus (MSRV) infection induced apoptosis and activated interferon signaling pathway in largemouth bass skin cells

Fish & Shellfish Immunology, 2018
Largemouth bass (Micropterus salmoides) rhabdovirus (MSRV) was isolated from infected juveniles of largemouth bass, and the infected fish exhibited corkscrew, irregular swimming, and crooked body. To our knowledge, the potential molecular mechanisms underlying the pathogenesis of MSRV infection remain largely unknown.
E-Bin, Gao, Guifang, Chen
openaire   +2 more sources

Emodin enhances host antiviral immunity against Micropterus salmoides rhabdovirus by activating RLR signaling in largemouth bass

Fish & Shellfish Immunology
Micropterus salmoides rhabdovirus (MSRV) is a highly pathogenic virus that causes substantial mortality in largemouth bass, yet effective antiviral agents remain unavailable. In this study, we evaluated the antiviral potential of 20 plant-derived small molecules and identified emodin as the most effective inhibitor.
Huan Wang   +7 more
openaire   +2 more sources

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