Results 121 to 130 of about 314 (153)

Galla Chinensis as an antiviral agent: Targeting Micropterus salmoides rhabdovirus infection

Fish & Shellfish Immunology
Being a major pathogen affecting the health of largemouth bass (Micropterus salmoides) aquaculture, Micropterus salmoides rhabdovirus (MSRV) causes significant economic losses. Galla chinensis, a traditional Chinese medicinal herb, possesses diverse biological activities, including antiviral properties.
Jieying, Yu, Mingzhu, Liu, Qing, Yu, Xiangmou, Qin, Mingming, Zhao, Ying, Pan, Nijia, Xue, Hao, Wang, Songlin, Li, Fei, Ling, Gaoxue, Wang, Shuyu, Han, Jingu, Shi, Lin, Huang, Pengfei, Li   +14 more
openaire   +2 more sources

Evaluation on the antiviral activity of aloe emodin against Micropterus salmoides rhabdovirus in vitro and in vivo

Aquaculture
Mingzhu Liu, Fei Ling, Tianqiang Liu
exaly   +2 more sources

Carbon nanotubes-loaded subunit vaccine can increase protective immunity against rhabdovirus infections of largemouth bass (Micropterus Salmoides)

Fish and Shellfish Immunology, 2020
Micropterus Salmoides rhabdovirus (MSRV), as a common aquatic animal virus, can cause lethal and epidemic diseases in the cultivation of largemouth bass. In this study, we reported a kind of immersion single-walled carbon nanotubes-loaded subunit vaccine which composited by glycoprotein (G) of MSRV, and evaluated its protective effect on largemouth ...
Zi-Rao Guo, Yi-Jun Jia
exaly   +3 more sources

Epigallocatechin gallate (EGCG) inhibits Micropterus salmoides rhabdovirus replication via suppressing viral attachment and infectivity

Fish & Shellfish Immunology
Micropterus salmoides rhabdovirus (MSRV) remains an economically important pathogen in the global largemouth bass industry, effective drugs to control the virus are still lacking. Epigallocatechin gallate (EGCG), the most abundant and bioactive catechin in green tea, possesses multiple biological activities, including widespread antiviral effects ...
Yuhang, Wang, Shuangshuang, Mao, Xiaoran, Feng, Reng, Qiu, Na, Li, Lunguang, Yao, Yinghui, Qin   +6 more
openaire   +2 more sources

Micropterus salmoides rhabdovirus (MSRV) infection induced apoptosis and activated interferon signaling pathway in largemouth bass skin cells

Fish & Shellfish Immunology, 2018
Largemouth bass (Micropterus salmoides) rhabdovirus (MSRV) was isolated from infected juveniles of largemouth bass, and the infected fish exhibited corkscrew, irregular swimming, and crooked body. To our knowledge, the potential molecular mechanisms underlying the pathogenesis of MSRV infection remain largely unknown.
E-Bin, Gao, Guifang, Chen
openaire   +2 more sources

Emodin enhances host antiviral immunity against Micropterus salmoides rhabdovirus by activating RLR signaling in largemouth bass

Fish & Shellfish Immunology
Micropterus salmoides rhabdovirus (MSRV) is a highly pathogenic virus that causes substantial mortality in largemouth bass, yet effective antiviral agents remain unavailable. In this study, we evaluated the antiviral potential of 20 plant-derived small molecules and identified emodin as the most effective inhibitor.
Huan Wang, Bingnan Gu, Zixuan Wang, Xu Zhang, Lipeng Shan, Lei Liu, Yang Hu, Jiong Chen   +7 more
openaire   +2 more sources

Study on the inhibitory effect of rocaglamide against Micropterus salmoides rhabdovirus (MSRV)

Aquaculture, 2023
Wenyan Zhang, Chen Li, Yujun Zhang, Yuanan Lu, Xueqin Liu   +4 more
openaire   +1 more source

Oral vaccination with recombinant Saccharomyces cerevisiae expressing Micropterus salmoides rhabdovirus G protein elicits protective immunity in largemouth bass

Fish & Shellfish Immunology
Micropterus salmoides rhabdovirus (MSRV) is one of the main pathogens of largemouth bass, leading to serious economic losses. The G protein, as the only envelope protein present on the surface of MSRV virion, contains immune-related antigenic determinants, thereby becoming the primary target for the design of MSRV vaccines.
Mao-Xia Yang, Jia-Hui Liang, Sheng Luo, Shi-Bo Zhang, Qian-Jin Zhou, Jian-Fei Lu, Jiong Chen   +6 more
openaire   +2 more sources

Natural product honokiol exhibits antiviral effects against Micropterus salmoides rhabdovirus (MSRV) both in vitro and in vivo

Journal of Fish Diseases
AbstractMicropterus salmoides rhabdovirus (MSRV) is a formidable pathogen, presenting a grave menace to juvenile largemouth bass. This viral infection frequently leads to epidemic outbreaks, resulting in substantial economic losses within the aquaculture industry. Unfortunately, at present, there are no commercially available vaccines or pharmaceutical
Fei Yang, Bin Yang, Kaige Song, Yingjie Jin, Gaoxue Wang, Pengfei Li, Qing Yu, Fei Ling   +7 more
openaire   +2 more sources

Palmatine as a potent immunomodulator: Enhancing resistance to Micropterus salmoides rhabdovirus in largemouth bass through innate immune activation and viral suppression

Fish & Shellfish Immunology
Micropterus salmoides rhabdovirus (MSRV) poses a significant threat to aquaculture, causing substantial economic losses. In this study, we evaluated the antiviral efficacy and immunomodulatory potential of palmatine, a plant-derived monomer, against MSRV infection in largemouth bass.
Huan Wang, Xu Zhang, Zixuan Wang, Lipeng Shan, Shiyi Zhu, Guanglu Liu, Lei Liu, Yang Hu, Jiong Chen   +8 more
openaire   +2 more sources