Results 71 to 80 of about 163 (110)

An avirulent Micropterus salmoides rhabdovirus vaccine candidate protects Chinese perch against rhabdovirus infection

Fish & Shellfish Immunology, 2018
In order to develop live vaccine against Siniperca chuatsi rhabdovirus (SCRV) disease, an avirulent virus strain, designed as Micropterus salmoides rhabdovirus Sanshui (MSRV-SS), was selected from six fish rhabdovirus isolates (SCRV-QY、SCRV-SS、SCRV-GM、CMRV-FS、OMBRV-JM、MSRV-SS) by fish challenge assay.
Zhang, Lijuan, Li, Ningqiu, Lin, Qiang, Liu, Lihui, Liang, Hongru, Huang, Zhibin, Fu, Xiaozhe   +6 more
openaire   +2 more sources

Rapid visual detection of Micropterus salmoides rhabdovirus using recombinase polymerase amplification combined with lateral flow dipsticks

Journal of Fish Diseases, 2022
AbstractLargemouth bass (Micropterus salmoides) is an important freshwater‐cultured species in China. Recently, a lethal and epidemic disease caused by Micropterus salmoides rhabdovirus (MSRV) results in huge economic losses to the largemouth bass industry. Current diagnostics for detecting MSRV are limited in sensitivity and speed and are inconvenient
Zizhao Feng, Xin Chu, Minzhen Han, Chenwei Yu, Yousheng Jiang, Hao Wang, Liqun Lu, Dan Xu   +7 more
openaire   +2 more sources

The recombinant subunit vaccine encapsulated by alginate‐chitosan microsphere enhances the immune effect against Micropterus salmoides rhabdovirus

Journal of Fish Diseases, 2022
AbstractThe disease caused by Micropterus salmoides rhabdovirus (MSRV) has brought substantial economic losses to the largemouth bass aquaculture industry in China. Vaccination was considered as a potential way to prevent and control this disease. As a kind of sustained and controlled release system, alginate and chitosan microspheres (SA‐CS) are ...
Fei‐Fan Xu, Fu‐Yi Jiang, Guo‐Qing Zhou, Jun‐Yao Xia, Fei Yang, Bin Zhu   +5 more
openaire   +2 more sources

Carbon nanotubes-loaded subunit vaccine can increase protective immunity against rhabdovirus infections of largemouth bass (Micropterus Salmoides)

Fish & Shellfish Immunology, 2020
Micropterus Salmoides rhabdovirus (MSRV), as a common aquatic animal virus, can cause lethal and epidemic diseases in the cultivation of largemouth bass. In this study, we reported a kind of immersion single-walled carbon nanotubes-loaded subunit vaccine which composited by glycoprotein (G) of MSRV, and evaluated its protective effect on largemouth ...
Zi-Rao, Guo, Zhao, Zhao, Chen, Zhang, Yi-Jun, Jia, De-Kui, Qiu, Bin, Zhu, Gao-Xue, Wang   +6 more
openaire   +2 more sources

Evaluation on the antiviral activity of ribavirin against Micropterus salmoides rhabdovirus (MSRV) in vitro and in vivo

Aquaculture, 2021
Abstract Micropterus salmoides rhabdovirus (MSRV) causes a severe lethal infection in largemouth bass fry, resulting in great economic loss. However, there is no effective drug to control this viral infection. In this study, a screening assay based on real-time quantitative PCR (RT-qPCR) was firstly performed, and the results showed that ribavirin ...
Fei Yang, Kaige Song, Zhongyu Zhang, Cheng Chen, Gaoxue Wang, Jiayun Yao, Fei Ling   +6 more
openaire   +1 more source

Quinoline, with the active site of 8‐hydroxyl, efficiently inhibits Micropterus salmoides rhabdovirus (MSRV) infection in vitro and in vivo

Journal of Fish Diseases, 2022
AbstractMicropterus salmoides rhabdovirus (MSRV) is an significant pathogen that causes high mortality and related economic losses in bass aquaculture. There is no effective or approved therapy to date. In this study, we evaluated the anti‐MSRV effects of 22 quinoline derivatives in grass carp ovary (GCO) cells.
Bo‐Yang Li, Fei Yang, Zhong‐Yu Zhang, Yu‐Feng Shen, Tao Wang, Liang Zhao, Jia‐Cheng Qin, Fei Ling, Gao‐Xue Wang   +8 more
openaire   +2 more sources

Micropterus salmoides rhabdovirus (MSRV) infection induced apoptosis and activated interferon signaling pathway in largemouth bass skin cells

Fish & Shellfish Immunology, 2018
Largemouth bass (Micropterus salmoides) rhabdovirus (MSRV) was isolated from infected juveniles of largemouth bass, and the infected fish exhibited corkscrew, irregular swimming, and crooked body. To our knowledge, the potential molecular mechanisms underlying the pathogenesis of MSRV infection remain largely unknown.
E-Bin, Gao, Guifang, Chen
openaire   +2 more sources

Oral vaccination with recombinant Saccharomyces cerevisiae expressing Micropterus salmoides rhabdovirus G protein elicits protective immunity in largemouth bass

Fish & Shellfish Immunology
Micropterus salmoides rhabdovirus (MSRV) is one of the main pathogens of largemouth bass, leading to serious economic losses. The G protein, as the only envelope protein present on the surface of MSRV virion, contains immune-related antigenic determinants, thereby becoming the primary target for the design of MSRV vaccines.
Mao-Xia Yang, Jia-Hui Liang, Sheng Luo, Shi-Bo Zhang, Qian-Jin Zhou, Jian-Fei Lu, Jiong Chen   +6 more
openaire   +2 more sources

Isolation and identification of a new strain Micropterus salmoides rhabdovirus (MSRV) from largemouth bass Micropterus salmoides in China

Aquaculture, 2023
Yinghui Qin, Peipei Zhang, Mengfan Zhang, Wenjing Guo, Si Deng, Haixiang Liu, Lunguang Yao   +6 more
openaire   +1 more source

Natural product honokiol exhibits antiviral effects against Micropterus salmoides rhabdovirus (MSRV) both in vitro and in vivo

Journal of Fish Diseases
AbstractMicropterus salmoides rhabdovirus (MSRV) is a formidable pathogen, presenting a grave menace to juvenile largemouth bass. This viral infection frequently leads to epidemic outbreaks, resulting in substantial economic losses within the aquaculture industry. Unfortunately, at present, there are no commercially available vaccines or pharmaceutical
Fei Yang, Bin Yang, Kaige Song, Yingjie Jin, Gaoxue Wang, Pengfei Li, Qing Yu, Fei Ling   +7 more
openaire   +2 more sources