Results 101 to 110 of about 497,158 (357)

Long noncoding RNAs in renal diseases

ExRNA, 2019
Long noncoding RNAs (lncRNAs) play critical roles in eukaryotic gene regulation and diseases, rather than being merely transcriptional “noise”. Over the past decade, the study of lncRNAs has emerged as a burgeoning field of research and expanded our ...
Minghui Liu, Jie Ren
doaj   +1 more source

Detection of microRNAs in color space [PDF]

, 2011
MotivationDeep sequencing provides inexpensive opportunities to characterize the transcriptional diversity of known genomes. The AB SOLiD technology generates millions of short sequencing reads in color-space; that is, the raw data is a sequence of ...
Altschul, Antonio Marco, Applied, Applied, Bartel, Berezikov, Cai, Chen, Cloonan, David, Flicek, Friedlander, Goff, Hofacker, Homer, Kozomara, Langmead, Li, Li, Li, Lowe, Marco, Mardis, Morin, Moxon, Robin, Ruby, Rumble, Sam Griffiths-Jones, Sasson   +29 more
core   +2 more sources

Response to Cadmium Toxicity: Orchestration of Polyamines and microRNAs in Maize Plant [PDF]

, 2023
Seyedeh Batool Hassani, Mojgan Latifi, Sasan Aliniaeifard, Shabnam Sohrabi Bonab, Neda Nasiri Almanghadim, Sara Jafari, Elham Mohebbifar, Anahita Ahangir, Maryam Seifikalhor, Hassan Rezadoost, Massimo Bosacchi, Anshu Rastogi, Françoise Bernard   +12 more
openalex   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Silencing Myostatin Using In Vivo Self‐Assembled siRNA Protects Against Cancer‐ and Dexamethasone‐Induced Muscle Atrophy

Advanced Healthcare Materials, EarlyView.
This study reports an in vivo self‐assembled siRNA strategy that enables the liver to generate small extracellular vesicles (sEVs) tagged with a muscle‐targeting peptide (MSP) and naturally loaded with myostatin (MSTN)‐siRNA. These MSP‐tagged sEVs are systemically delivered to skeletal muscle, efficiently silence MSTN, promote muscle hypertrophy, and ...
Xin Yin, Azhar Anwar, Jiehao Chen, Qinghao Sun, Likun Zhou, Jie Tang, Jingwei Guo, Linbo Yan, Yongci Chen, Feng Yin, Chen‐Yu Zhang, Zigang Li, Jizheng Ma, Liyuan Sheng, Xi Chen   +14 more
wiley   +1 more source

The miR-28-5p Targetome Discovery Identified SREBF2 as One of the Mediators of the miR-28-5p Tumor Suppressor Activity in Prostate Cancer Cells

Cells, 2020
miR-28-5p is downregulated in some tumor tissues in which it has been demonstrated to have tumor suppressor (TS) activity. Here, we demonstrate that miR-28-5p acts as a TS in prostate cancer (PCa) cells affecting cell proliferation/survival, as well as ...
Sofia Fazio, Gabriele Berti, Francesco Russo, Monica Evangelista, Romina D’Aurizio, Alberto Mercatanti, Marco Pellegrini, Milena Rizzo   +7 more
doaj   +1 more source

FUS mutant human motoneurons display altered transcriptome and microRNA pathways with implications for ALS pathogenesis [PDF]

, 2017
The FUS gene has been linked to amyotrophic lateral sclerosis (ALS). FUS is a ubiquitous RNA-binding protein, and the mechanisms leading to selective motoneuron loss downstream of ALS-linked mutations are largely unknown.
Alfano, Vincenzo, Bozzoni, Irene, Colantoni, Alessio, DE SANTIS, Riccardo, DE TURRIS, Valeria, Peruzzi, Giovanna, Rosa, Alessandro, Santini, Laura   +7 more
core   +2 more sources

MicroRNA immunobiology: when microRNA chemists meet immunologists [PDF]

Cellular & Molecular Immunology, 2011
Although interdisciplinary research has been heralded as the engine of basic discovery for decades, many in the immunology community have been taken back by the recent marriage between microRNA (miRNA) and immunology. MicroRNAs were first discovered by Ambros and colleagues in 1993.1 They are small untranslated RNAs, highly conserved between different ...
openaire   +2 more sources

Prospective Assessment of Systemic MicroRNAs as Markers of Response to Neoadjuvant Chemotherapy in Breast Cancer [PDF]

, 2020
Andrew McGuire, Máire‐Caitlín Casey, Ronan Waldron, Helen Heneghan, O. Kalinina, Emma Holian, Ailbhe M. McDermott, Aoïfe Lowery, John Newell, Róisín M. Dwyer, Nicola Miller, Maccon Keane, James A. L. Brown, Michael J. Kerin   +13 more
openalex   +1 more source

MicroRNA in HCC: Biomarkers and Therapeutic Targets [PDF]

, 2021
Zheng Wang, Yongxia He, Yuwei Song, Yue Wang, Feng Chen   +4 more
openalex   +1 more source