Results 81 to 90 of about 294,358 (306)

miRNA-21-5p is an important contributor to the promotion of injured peripheral nerve regeneration using hypoxia-pretreated bone marrow–derived neural crest cells

open access: yesNeural Regeneration Research, 2023
Our previous study found that rat bone marrow–derived neural crest cells (acting as Schwann cell progenitors) have the potential to promote long-distance nerve repair.
Meng Cong   +11 more
doaj   +1 more source

Body fluid mixtures; resolution using forensic microRNA analysis [PDF]

open access: yes, 2013
Body fluid identification is a crucial aspect of forensic biology; particularly in sexual assaults which is usually characterised as a mixture of body fluids.
World, Damien   +5 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

In-Plant Insect-Proofing by Trans-Kingdom RNAi

open access: yesProceedings, 2020
Helicoverpa armigera, the cotton bollworm, is a major insect pest for a wide range of agriculturalcrops. [...]
Julia Bally   +5 more
doaj   +1 more source

MicroRNAs in hemostasis [PDF]

open access: yesJournal of Thrombosis and Haemostasis, 2015
Epidemiologic studies have revealed that modification of the levels of individual components of the hemostatic system may have effects on the development of thrombosis or hemorrhage. To maintain the necessary equilibrium, the hemostatic system is finely regulated.
Teruel-Montoya, R.   +2 more
openaire   +3 more sources

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

MicroRNA-27a/b Negatively Regulates Hepatic Gluconeogenesis by Targeting FOXO1

open access: yes, 2019
Supplemental figures refer to the manuscript titled ‘MicroRNA-27a/b Negatively Regulates Hepatic Gluconeogenesis by Targeting ...
Shuyue Wang (833511)   +10 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

In vivo self-assembly of small RNAs in extracellular vesicles: a commentary on a new therapeutic paradigm [PDF]

open access: yesExRNA
Extracellular vesicles (EVs) can transport functional RNA, but the clinical development of EV-based RNA therapeutics has been constrained by the technical demands of ex vivo production and cargo loading.
Azhar Anwar, Xin Yin, Xi Chen
doaj   +1 more source

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