Results 61 to 70 of about 294,358 (306)

Identification of differentially expressed miRNAs and their target genes in response to brassinolide treatment on flowering of tree peony (Paeonia ostii)

open access: yesPlant Signaling & Behavior, 2022
Tree peony is a famous flower plant in China, but the short and concentrated flowering period limits its ornamental value and economic value. Brassinolide (BR) plays an important role in plant growth and development including flowering. There have been a
Lin Zhang   +5 more
doaj   +1 more source

MicroRNAs and Atherosclerosis [PDF]

open access: yesCurrent Atherosclerosis Reports, 2013
MicroRNAs (miRNAs) are small, ~22 nucleotide (nt) sequences of RNA that regulate gene expression at posttranscriptional level. These endogenous gene expression inhibitors were primarily described in cancer but recent exciting findings have also demonstrated a key role in cardiovascular diseases (CVDs), including atherosclerosis.
Julio, Madrigal-Matute   +3 more
openaire   +2 more sources

Considering the effect of stem-loop reverse transcription and quantitative PCR analysis of blood and saliva specific microRNA markers upon mixed body fluid stains [PDF]

open access: yes, 2013
Forensic RNA analysis is gathering pace with reports of messenger RNA analysis being used in case work, and with microRNA being increasingly researched.
Uchimoto, M.L.   +10 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Crosstalk between KRAS and miRNA in cancer [PDF]

open access: yesExRNA
Kirsten RAS viral oncogene homolog (KRAS) is one of the most frequently mutated oncogenes in human cancers. Its mutations result in constitutive activation of the protein, which drives the mitogen-activated protein kinase (MAPK) and phosphoinositide 3 ...
Ruoming Shen   +4 more
doaj   +1 more source

miREE: miRNA Recognition Elements Ensemble [PDF]

open access: yes, 2011
Background Computational methods for microRNA target prediction are a fundamental step to understand the miRNA role in gene regulation, a key process in molecular biology. In this paper we present miREE, a novel microRNA target prediction tool.
Enrico Macii   +12 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Acute responses of circulating microRNAs to low-volume sprint interval cycling

open access: yesFrontiers in Physiology, 2015
Low-volume high-intensity interval training is an efficient and practical method of inducing physiological responses in various tissues to develop physical fitness and may also change the expression of circulating microRNAs (miRNAs).
Shu Fang eCui   +10 more
doaj   +1 more source

MicroRNAs in Cholangiopathies [PDF]

open access: yesCurrent Pathobiology Reports, 2014
Cholangiocytes, the cells lining bile ducts, comprise a small fraction of the total cellular component of the liver, yet perform the essential role of bile modification and transport of biliary and blood constituents. Cholangiopathies are a diverse group of biliary disorders with the cholangiocyte as the target cell; the etiopathogenesis of most ...
Steven P, O'Hara   +4 more
openaire   +2 more sources

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