Results 51 to 60 of about 294,358 (306)

microRNA-767 and its binding site polymorphism in mTOR gene act as potential biomarkers for female reproductive cancers - supplementary material

open access: yes, 2023
Supplementary Table 1: Demographic and histopathological parameters of cases and controls.Supplementary Table 2: Primers for microRNA-767, U6 and Tetra-ARMS PCR primers for mTOR(rs2536) SNPSupplementary Table 3: PCR conditions for tetra arms ...
Ishrat Mahjabeen (846545)   +10 more
core   +1 more source

The Jun/miR-22/HuR regulatory axis contributes to tumourigenesis in colorectal cancer

open access: yesMolecular Cancer, 2018
Background Colorectal cancer (CRC) is a severe health problem worldwide. Clarifying the mechanisms for the deregulation of oncogenes and tumour suppressors in CRC is vital for its diagnosis, treatment, prognosis and prevention.
Yanqing Liu   +18 more
doaj   +1 more source

Viral infection and neurological disorders—potential role of extracellular nucleotides in neuroinflammation [PDF]

open access: yesExRNA, 2019
Neuroinflammation can be induced under several conditions including pathogen infection such as virus. As the main immune cells in brain, microglia activation plays a pivotal role in neuroinflammation by responding to the invading pathogens (viral DNA/RNA)
Liang Li   +4 more
doaj   +1 more source

LINC00460-miR-149-5p/miR-150-5p-Mutant p53 Feedback Loop Promotes Oxaliplatin Resistance in Colorectal Cancer

open access: yesMolecular Therapy: Nucleic Acids, 2020
Oxaliplatin resistance is a major challenge in the clinical treatment for advanced colorectal cancer (CRC). Long non-coding RNAs (lncRNAs) are involved in tumorigenesis and progression as critical regulators, while their potential roles in ...
Xiangfeng Meng   +8 more
doaj   +1 more source

MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival [PDF]

open access: yes, 2011
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work
Hatton, CSR   +45 more
core   +1 more source

Fasting induces a subcutaneous-to-visceral fat switch mediated by microRNA-149-3p and suppression of PRDM16

open access: yesNature Communications, 2016
Visceral adiposity is associated with metabolic diseases, whereas subcutaneous adiposity is comparatively benign. Here, the authors report that subcutaneous adipose tissue adopts visceral-like characteristics in response to prolonged fasting, and show ...
Hanying Ding   +12 more
doaj   +1 more source

Application Prospect of MicroRNA in Skin Wound Age Estimation

open access: yesFayixue Zazhi, 2021
Wound age estimation is one of the major tasks in forensic practice. However, relatively accurate estimation of the wound age is still a conundrum and research spotlight world-widely. Studies show that microRNAs (miRNAs) are involved in the whole process
CHENG Jian   +4 more
doaj   +1 more source

MicroRNAs in plants [PDF]

open access: yesGenes & Development, 2002
MicroRNAs (miRNAs) are an extensive class of ∼22-nucleotide noncoding RNAs thought to regulate gene expression in metazoans. We find that miRNAs are also present in plants, indicating that this class of noncoding RNA arose early in eukaryotic evolution. In this paper 16 Arabidopsis miRNAs are
Brenda J, Reinhart   +4 more
openaire   +2 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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