Results 121 to 130 of about 282,025 (323)

ExprTarget: An Integrative Approach to Predicting Human MicroRNA Targets [PDF]

open access: yesGamazon ER, Im H-K, Duan S, Lussier YA, Cox NJ, Dolan ME, Zhang W. ExprTarget: An integrative approach to predicting human microRNA targets. PLoS ONE. 2010; 5(10): e13534, 2013
We developed an online database, ExprTargetDB, of human miRNA targets predicted by an approach that integrates gene expression profiling into a broader framework involving important features of miRNA target site predictions.
arxiv  

Targeting Decidual CD16+ Immune Cells with Exosome‐Based Glucocorticoid Nanoparticles for Miscarriage

open access: yesAdvanced Science, EarlyView.
Exosome‐based nanoparticles (GC‐Exo‐CD16Ab) are designed to deliver glucocorticoids (GC) specifically to decidual CD16+ NK cells and macrophages. This targeted delivery effectively suppresses the cytotoxicity of decidual NK cells, inhibits M1 macrophage polarization, and modulates the decidual microenvironment.
Linlin Wang   +17 more
wiley   +1 more source

MicroRNA-1276 Promotes Colon Cancer Cell Proliferation by Negatively Regulating LACTB

open access: yesCancer Management and Research, 2020
Chunxiao Wang,* Zesheng Shi,* Zhongshi Hong, Jianpeng Pan, Zhichuan Chen, Chengzhi Qiu, Haibin Zhuang, Xuecong Zheng Department of General Surgery, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, People’s Republic of China ...
Wang C   +7 more
doaj  

Effect of two Exercise Training Protocols on miR-133a and Runx2 in High-Fat Diet and Streptozotocin-induced Diabetes

open access: yesResearch in Molecular Medicine, 2021
Background: Type 2 Diabetes (T2D) in the elderly is an epidemic that significantly impacts global health. This experimental study aimed to compare the responses of microRNA-133a (miR-133a) in different tissues and of Runt-related transcription factor 2 ...
Maryam Asadi Farsani   +4 more
doaj  

Communities of dense weighted networks: MicroRNA co-target network as an example [PDF]

open access: yesarXiv, 2014
Complex networks are intrinsically modular. Resolving small modules is particularly difficult when the network is densely connected; wide variation of link weights invites additional complexities. In this article we present an algorithm to detect community structure in densely connected weighted networks.
arxiv  

Rapid Generation of MicroRNA Sponges for MicroRNA Inhibition

open access: yesPLoS ONE, 2012
MicroRNA (miRNA) sponges are transcripts with repeated miRNA antisense sequences that can sequester miRNAs from endogenous targets. MiRNA sponges are valuable tools for miRNA loss-of-function studies both in vitro and in vivo. We developed a fast and flexible method to generate miRNA sponges and tested their efficiency in various assays. Using a single
Annelies Adema   +9 more
openaire   +6 more sources

Apoptotic Vesicles Derived from Mesenchymal Stem Cells Ameliorate Hypersensitivity Responses via Inducing CD8+ T Cells Apoptosis with Calcium Overload and Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
The therapeutic potential of ApoVs derived from stem cells from human exfoliated deciduous teeth (SHED‐ApoVs) in the treatment of CD8+ T cell‐mediated hypersensitivity reactions is noteworthy. SHED‐ApoVs are capable of fusing with the plasma membrane of CD8+ T cells, which subsequently triggers a series of events characterized by calcium overload ...
Anqi Liu   +13 more
wiley   +1 more source

MicroRNAs as Quality Assessment Tool in Stored Packed Red Blood Cell in Blood Banks

open access: yesJournal of Blood Medicine, 2023
Zewudu Mulatie,1 Melak Aynalem,2 Solomon Getawa2 1Department of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, Desie, Ethiopia; 2Department of Hematology and Immunohematology, School of Biomedical and Laboratory ...
Mulatie Z, Aynalem M, Getawa S
doaj  

miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs [PDF]

open access: gold, 2002
Zissimos P. Mourelatos   +8 more
openalex   +1 more source

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