Results 151 to 160 of about 282,025 (323)

MicroRNA‐433‐3p enhances chemosensitivity of glioma to cisplatin by downregulating NR5A2

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
miR‐433‐3p mediated the ability of NR5A2 to regulate the malignant behavior of glioma cells Abstract Objective We attempted to investigate influence of microRNA‐433‐3p on malignant progression of glioma and identify its molecular mechanism, thus laying groundwork for glioma management.
Jun Li, Jingshun Gu, Juntong Wang, Aiwu You, Yuyan Zhang, Guomin Rao, Shuang Li, Xuehua Ge, Kun Zhang, Dongchun Wang   +9 more
wiley   +1 more source

MicroRNAs: A Role in Plant Development [PDF]

, 2003
Sarah Hake
openalex   +1 more source

Engineering the Immune Response to Biomaterials

Advanced Science, EarlyView.
This paper reviews immune responses to biomaterials, stages of evolution in relation to managing these responses ranging from preventing to modulating them. It also discusses state‐of‐the‐art strategies to modulate these responses and modes of their delivery.
Abolfazl Salehi Moghaddam, Mehran Bahrami, Einollah Sarikhani, Rumeysa Tutar, Yavuz Nuri Ertas, Faleh Tamimi, Ali Hedayatnia, Clotilde Jugie, Houman Savoji, Asma Talib Qureshi, Muhammad Rizwan, Chima V. Maduka, Nureddin Ashammakhi   +12 more
wiley   +1 more source

Poor expression of miR‐195‐5p can assist the diagnosis of cerebral vasospasm after subarachnoid hemorrhage and predict adverse outcomes

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Objective Patients with spontaneous subarachnoid hemorrhage (SAH) may develop refractory arterial cerebral vasospasm (CVS), which is the leading cause of death in SAH patients. This study explored the clinical diagnostic value of serum miR‐195‐5p levels in CVS after SAH (SAH + CVS) and its relationship with the prognosis of SAH + CVS.
Yong Li, Senyuan Yang, Xiaobin Zhou, Runlong Lai   +3 more
wiley   +1 more source

microRNAs in aged sperm confer psychiatric symptoms to offspring through causing the dysfunction of estradiol signaling in early embryos

Cell Discovery, 2022
Gaoli Liang, Xiaoju Zhu, Zixuan Zhang, Li Chen, Huijin Feng, Shoubin Zhan, Huanhuan Hu, Ranran Yu, Chen-Yu Zhang, Zhichun Feng, Bing Yao, Yanbo Wang, Xi Chen   +12 more
doaj   +1 more source

The C. elegans hunchback Homolog, hbl-1, Controls Temporal Patterning and Is a Probable MicroRNA Target [PDF]

, 2003
Shin-Yi Lin, Steven Johnson, Mary C. Abraham, Monica C. Vella, Amy E. Pasquinelli, Chiara Gamberi, Ellen Gottlieb, Frank J. Slack   +7 more
openalex   +1 more source

Targeted DNA Nanomachine Enables Specific miRNA‐Responsive Singlet Oxygen Amplification for Precise Cutaneous Squamous Cancer Therapy

Advanced Science, EarlyView.
An intelligent DNA nanomachine based on DNA tetrahedron is proposed, incorporated with aptamer and specific miRNA‐responsive hairpin catalytic assembly (HCA), for precise therapy of cutaneous squamous cell carcinoma (cSCC) in mice, with barely systemic toxicity and inflammation.
Hanane Aliouat, Detian Zhang, Lanyuan Peng, Jiaxin Huang, Hongshi Cheng, Jiaojiao Zhu, Xiang Chen, Nuli Xie, Wenhu Zhou, Shuang Zhao   +9 more
wiley   +1 more source

MiR‐30b‐5p attenuates the inflammatory response and facilitates the functional recovery of spinal cord injury by targeting the NEFL/mTOR pathway

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Silencing of NEFL inhibits the inflammatory response and functional recovery following spinal cord injury. Abstract Background Neurofilament light chain (NEFL) has been identified as a biomarker for spinal cord injury (SCI), but its effect and underlying mechanism in SCI remain unclear.
Hui Zhang, Duojun Wang, Jinyu Tong, Jianguo Fang, Zaijun Lin   +4 more
wiley   +1 more source

Regulation of Flowering Time and Floral Organ Identity by a MicroRNA and Its APETALA2-Like Target Genes [PDF]

, 2003
Milo J. Aukerman, Hajime Sakai
openalex   +1 more source

M6A Modified miR‐31‐5p Suppresses M1 Macrophage Polarization and Autoimmune Dry Eye by Targeting P2RX7

Advanced Science, EarlyView.
The upregulation of FTO in autoimmune dry eye suppresses the recognition of pri‐miR‐31 by DGCR8, thereby inhibiting the maturation of miR‐31‐5p and reducing its inhibitory effect on the target gene P2RX7. The activation of P2RX7 subsequently triggers the p38 MAPK signaling pathway and increases the level of M1‐related genes, thus exacerbating the ...
Lu Zhao, Xuejia Li, Min Gao, Lin Liu, Binyun Ma, Xun Liu, Jiachen Zhang, Ruoxuan Liu, Bei Du, Ruihua Wei, Hong Nian   +10 more
wiley   +1 more source