Results 171 to 180 of about 498,599 (357)
MicroRNA-7 enhances cytotoxicity induced by gefitinib in non-small cell lung cancer via inhibiting the EGFR and IGF1R signalling pathways [PDF]
, 2015 Jungang Zhao, Wan-fu Men, Jun Tang
openalex +1 more source
Advanced Science, EarlyView.To precisely modulate natural and synthetic regulatory parts, SUPER is introduced as a sophisticated and tunable controller of genetic devices without requiring sequence modification on the target. SUPER enhances dynamic range of RNA‐, chemical‐, temperature‐, and protein‐responsive biosensors up to 1011%, and converts biosensors to cover an expanded ...
Taeyang Heo +3 more
wiley +1 more source
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Advanced Science, EarlyView.Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
Analyzing the expression of candidate microRNAs in primary tumors of oral squamous cell carcinoma [PDF]
, 2014 Mayakannan Manikandan +2 more
openalex +1 more source
MicroRNA in the Diagnosis and Treatment of Doxorubicin-Induced Cardiotoxicity [PDF]
, 2023 Ziyu Kuang +5 more
openalex +1 more source
EGR Proteins Mediate Interferon‐Independent Anti‐HSV‐1 Responses Through Viral and Host Targets
Advanced Science, EarlyView.Early antiviral responses are typically mediated by interferons. However, during HSV‐1 infection, host early growth response (Egr) genes, which are not interferon‐stimulated genes, are quickly induced by viral protein ICP0. EGR proteins, in turn, suppress viral lytic infection by activating viral latency‐associated (LAT) and host immune regulatory ...
Shuaishuai Wang +4 more
wiley +1 more source
Macrophage microRNA-150 promotes pathological angiogenesis as seen in age-related macular degeneration [PDF]
, 2018 Agarwal +11 more
core +2 more sources
Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics
Advanced Science, EarlyView.The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu +4 more
wiley +1 more source