Results 171 to 180 of about 661,223 (352)

Deep belief network–Based Matrix Factorization Model for MicroRNA-Disease Associations Prediction [PDF]

, 2020
Yulian Ding, Fei Wang, Xiujuan Lei, Bo Liao, Fang‐Xiang Wu   +4 more
openalex   +1 more source

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

Role of microRNAs in hepatocellular carcinoma [PDF]

, 2015
Huixiong Xu
openalex   +1 more source

MicroRNA targeting specificity in mammals: determinants beyond seed pairing.

Molecules and Cells, 2007
Andrew Grimson, K. Farh, W. K. Johnston, P. Garrett-engele, Lee P. Lim, D. Bartel   +5 more
semanticscholar   +1 more source

Dysregulation of CircZNF79(5) Modulates YBX1 Stability and Selective Autophagy to Drive Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
In HCC, circZNF79(5) binds to YBX1 and functions as an oncogene, recruits BRCC36 to remove K63‐linked ubiquitin chains to stabilize YBX1 protein, and promotes HCC progression via the HIF‐1 signaling pathway. Conversely, circZNF79(5) silencing activates the AMPK/mTOR pathway, inducing p62‐mediated selective autophagic degradation of YBX1.
Xueqiang Guo, Lingling Xi, Yukun Liu, Wenbao Lv, Tianzi Li, Andong Ju, Zhenlin Fan, Yaping Shen, Zhuang Qian, Weiyun Wang, Zhuo Liang, Wenjuan Song, Kaiwen Chang, Shuangping Ma, Junhe Zhang, Tao Han, Kun You, Cunshuan Xu, Lei Wang, Weisheng Guo, Wenjie Ren   +20 more
wiley   +1 more source

MicroRNA 543 suppresses breast cancer cell proliferation, blocks cell cycle and induces cell apoptosis via direct targeting of ERK/MAPK

, 2017
Po Chen, Wentao Xu, Yi Luo, Yi Zhang, Yi He, Shuo Yang, Zhijun Yuan   +6 more
openalex   +2 more sources

Methylation of microRNA-338-5p by EED promotes METTL3-mediated translation of oncogene CDCP1 in gastric cancer

, 2021
Fangbin Zhang, Yan Yan, Xinguang Cao, Jinping Zhang, Yingxia Li, Changqing Guo   +5 more
openalex   +2 more sources

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

Advanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir, Elliot Thouvenot, Giacomo Gropplero, Léonie Dec, Damarys Loew, Clotilde Théry, Jose E Perez, Claire Wilhelm   +7 more
wiley   +1 more source

MicroRNAs in pancreatic malignancy: Progress and promises

, 2014
Sanjeev K. Srivastava, Sumit Arora, Seema Singh, Arun Bhardwaj, Courey Averett, Ajay P. Singh   +5 more
openalex   +1 more source

Feedback networks between microRNAs and epigenetic modifications in urological tumors [PDF]

, 2012
Julia Liep, Anja Rabien, Klaus Jung
openalex   +1 more source