Results 191 to 200 of about 208,863 (269)

MicroRNA-Mediated Obstruction of Stem-loop Alternative Splicing (MIMOSAS) regulates long-range alternative splicing in Drosophila. [PDF]

Nucleic Acids Res
Ruan K, Liu J, Xia M, Bertolotti F, Hofacker I, Wuchty S, Zhai RG.   +6 more
europepmc   +1 more source

Evaluation of on‐ and off‐target effects of self‐assembled epidermal growth factor receptor small interfering RNA delivery system

Clinical and Translational Medicine
Hongyuan Guo, Yuanyuan Su, Ruoyan Zhang, Xiao Hu, Hao Zhu, Xin Yan, Chen‐Yu Zhang, Xu Guo, Zhen Zhou, Xi Chen   +9 more
doaj   +1 more source

Transgenerational Epigenetic Effect of Cryopreservation of F0 Rooster Sperm (<i>Gallus gallus domesticus</i>) on microRNA-Regulation and Histological Parameters of the Reproductive System of F1 Offspring. [PDF]

Animals (Basel)
Ivershina A, Silyukova Y, Fedorova E, Chugunova E, Mirzakaeva I, Modina A, Stanishevskaya O.   +6 more
europepmc   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

[Retracted] Prognostic and predictive roles of microRNA‑411 and its target STK17A in evaluating radiotherapy efficacy and their effects on cell migration and invasion via the p53 signaling pathway in cervical cancer. [PDF]

Mol Med Rep
Wei W, Liu C.
europepmc   +1 more source

De‐Escalation of Neoadjuvant Treatment for HER2‐Positive Breast Cancer

International Journal of Cancer, EarlyView.
ABSTRACT With improved prognosis in early HER2‐positive breast cancer, safely de‐escalating treatment is increasingly investigated to minimize overtreatment. This article focuses on neoadjuvant de‐escalation strategies for HER2‐positive breast cancer.
Yiyin Ma, Dedian Chen, Sheng Huang
wiley   +1 more source

Retraction: Silencing microRNA-27a inhibits proliferation and invasion of human osteosarcoma cells through the SFRP1-dependent Wnt/β-catenin signaling pathway. [PDF]

Biosci Rep
Shi Y, Li J, Mu Y, Zhang L, Chen X, Chen S.   +5 more
europepmc   +1 more source

Epigenetic Dysregulation of Somatostatin Receptors (SSTR) 1–5 and Therapeutic Implications in Neuroendocrine and Non‐Neuroendocrine Malignancies

International Journal of Cancer, EarlyView.
ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari, Pablo Hoffmann, Laura Reichl, Maximilian Schmutz, Nina Fischer, Thi Tuong Vi Dang, Fulvia Ferrazzi, Pascal Johann, Michaela Kuhlen, Constantin Lapa, Rainer Claus   +10 more
wiley   +1 more source

Comparison of Relapse Risk Prediction Models During Active Surveillance in Stage I Seminoma: A Retrospective Multicenter Cohort Study

International Journal of Cancer, EarlyView.
ABSTRACT To improve the prediction of relapse for clinical stage I seminoma, we aimed to validate the Boormans model (incorporating tumor size, rete testis invasion, and lymphovascular invasion) against the conventional classification (tumor size > 4 cm/rete testis invasion).
Andreas Banner, Eveline Daetwyler, Stefanie Fischer, Stephanie Schöpfer‐Schwab, Karl Pemberger, Michael Scholz, Kathrin Olesch, David Oswald, Angelina Strauch, Tim Nestler, Lukas Koren‐Wagner, Robin Zeder, Clemens Mikulits, Sebastian Lenart, Christoph Seidel, Angelika Terbuch   +15 more
wiley   +1 more source

Circulatory microRNA signature distinguishing rheumatoid arthritis and psoriatic arthritis. [PDF]

Rheumatology (Oxford)
Tynan Ó, Hanlon MM, Floudas A, Wade S, Fearon U, Veale DJ.   +5 more
europepmc   +1 more source