Results 181 to 190 of about 661,223 (352)

Nasal Mucosa‐Derived Extracellular Vesicles as a Systemic Antiaging Intervention

Advanced Science, EarlyView.
This study shows that nasal mucosa‐derived extracellular vesicles (nmEVs) exert systemic anti‐ageing effects in mice by restoring circadian rhythm, suppressing cellular senescence, and improving cognitive function. In aged human bone marrow mesenchymal stem cells, nmEVs reverse senescence‐associated phenotypes and reactivate core clock gene expression.
Wentao Shi, Lu Bian, Mengyuan Yu, Jun Wang, Mingzhu Gao, Liping Shen, Xiao Zhang, Zhiliang Huang, Hong Tang, Long Lv, Yunduan Que, Zengli Miao, Xuechao Wu, Qing Wang, Xiaojie Lu   +14 more
wiley   +1 more source

Sputum Exosomal microRNAs Profiling Reveals Critical Pathways Modulated By Pseudomonas aeruginosa Colonization In Bronchiectasis

International Journal of COPD, 2019
Yan Huang,1 Chun-lan Chen,1 Jing-jing Yuan,1 Hui-min Li,1 Xiao-rong Han,1 Rong-chang Chen,2 Wei-jie Guan,1 Nan-shan Zhong1 1Department of Respiratory Medicine, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory
Huang Y, Chen C, Yuan J, Li H, Han X, Chen R, Guan W, Zhong N   +7 more
doaj  

Prediction of Mammalian MicroRNA Targets

Cell, 2003
B. P. Lewis, I. Shih, M. Jones-Rhoades, D. Bartel, C. Burge   +4 more
semanticscholar   +1 more source

Cancer Biology of GSPT1: Mechanisms and Targeted Therapy Opportunities of Molecular Glue Degraders

Advanced Science, EarlyView.
This review systemically summarizes the structure, expression, regulatory networks, and isoform‐specific signaling of GSPT1 in cancers. According to the integration of GSPT1 targeted therapies, current challenges of GSPT1 targeted therapies are further analyzed, and provide therapeutic opportunities for the application of GSPT1 degraders in precision ...
Qiqi Lin, Wenjing Liu, Wenjia Lu, Monong Zhao, Lin Cao, Zhiyu Li, Jubo Wang, Xi Xu, Hongxi Wu   +8 more
wiley   +1 more source

Hepatitis-C-virus-induced microRNAs dampen interferon-mediated antiviral signaling

, 2016
Abigail Jarret, Adelle P. McFarland, Stacy M. Horner, Alison M. Kell, Johannes Schwerk, MeeAe Hong, Samantha Badil, Rochelle C Joslyn, Darren P. Baker, Mary Carrington, Curt H. Hagedorn, Michael Gale, Ram Savan   +12 more
openalex   +1 more source

Biomarker-based approach to determine etiology and severity of pulmonary hypertension: Focus on microRNA [PDF]

, 2022
Sylwester Rogula, Bartosz Pomirski, Norbert Czyżak, Ceren Eyileten, Marek Postuła, Łukasz Szarpak, Krzysztof J. Filipiak‬, Marcin Kurzyna, Miłosz Jaguszewski, Tomasz Mazurek, Marcin Grabowski, Aleksandra Gąsecka   +11 more
openalex   +1 more source

Red Blood Cell‐Derived Exosomal miR‐93‐5p Promotes Lung Cancer Progression through PTEN Suppression

Advanced Science, EarlyView.
Red blood cell (RBC)‐derived exosomal miR‐93‐5p is elevated in lung cancer patients and correlates with poor outcomes. Exosomal miR‐93‐5p suppresses PTEN in cancer cells, enhancing proliferation, migration, and invasion. In mouse models, therapeutic inhibition with ASO‐miR‐93 5p reduces tumor growth, highlighting a bidirectional tumor‐RBC‐tumor axis ...
Ning Li, Pushpa Dhilipkannah, Van K Holden, Ashutosh Sachdeva, Feng Jiang   +4 more
wiley   +1 more source

MicroRNA-106a Provides Negative Feedback Regulation in Lipopolysaccharide-Induced Inflammation by targeting TLR4 [PDF]

, 2019
Jing Yang, Yu Chen, Kangfeng Jiang, Yaping Yang, Gan Zhao, Shuai Guo, Ganzhen Deng   +6 more
openalex   +1 more source

Case report: MicroRNA-10b as a therapeutic target in feline metastatic mammary carcinoma and its implications for human clinical trials [PDF]

, 2022
N. Anna Savan, Paulo Vilar Saavedra, Alan Halim, Vilma Yuzbasiyan‐Gurkan, Ping Wang, Byunghee Yoo, Matti Kiupel, Lorenzo F. Sempere, Zdravka Medarova, Anna Moore   +9 more
openalex   +1 more source

RAS Is Regulated by the let-7 MicroRNA Family

Cell, 2005
Steven M. Johnson, H. Grosshans, Jaclyn Shingara, M. Byrom, R. Jarvis, Angie Cheng, E. Labourier, Kristy L. Reinert, D. Brown, F. Slack   +9 more
semanticscholar   +1 more source