Dual Disruption of the Immune Cytokine Spätzle Facilitates Fungal Infection of Diverse Insect Hosts
The Toll pathway is essential for insect defense against fungal pathogens. This works reports that fungal parasites employ two divergent virulent effectors to target the Toll receptor ligand Spätzle: a metalloprotease degrading it and a hairpin‐like effector hijacking it to block signal transduction. This dual strategy enables the fungus to kill a wide
Shuangxiu Song +7 more
wiley +1 more source
RETRACTED: Zhang et al. MicroRNA-378 Alleviates Cerebral Ischemic Injury by Negatively Regulating Apoptosis Executioner Caspase-3. <i>Int. J. Mol. Sci.</i> 2016, <i>17</i>, 1427. [PDF]
Zhang N +5 more
europepmc +1 more source
This report describes a nano magnesium nourisher, named MgC@PS, capable of targeted Mg2⁺ delivery to macrophages, effectively suppressing The nuclear factor kappa B (NF‐κB) activation and mitigating NLRP3 inflammasome‐driven pyroptosis in liver inflammation.
Li Wang +13 more
wiley +1 more source
Co-regulatory Network of Transcription Factors and miRNAs in Colorectal Cancer Pathogenesis [PDF]
Mohammad Hasan Soheilifar +3 more
doaj +1 more source
Circulating Molecular Biomarkers for the Diagnosis and Monitoring of NSCLC-A Review. [PDF]
Jelski W +3 more
europepmc +1 more source
A microRNA expression signature of human solid tumors defines cancer gene targets
S. Volinia +17 more
semanticscholar +1 more source
Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro +6 more
wiley +1 more source
Knowing is not enough; we must apply: the case for rigorous microRNA annotation standards. [PDF]
Hackenberg M +4 more
europepmc +1 more source
Genomics, microRNA, epigenetics, and proteomics for future diagnosis, treatment and monitoring response in upper GI cancers [PDF]
Björn L.D.M. Brücher +9 more
openalex +1 more source

