Results 221 to 230 of about 505,053 (355)

USB1 deficiency disrupts neutrophil maturation via RNA dysregulation independent of global pre‐mRNA splicing

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the essential role of USB1 in neutrophil maturation. In normal myeloid cells, USB1 acts as an RNA exonuclease, trimming RNA tails to maintain proper RNA network function, which supports the differentiation of myeloid progenitor cells into mature neutrophils.
Hang Li, Guiying Shi, Jiaming Tang, Yiying Huang, Jie Wang, Xuepei Lei, Lin Bai   +6 more
wiley   +1 more source

[Retracted] MicroRNA‑486‑5p inhibits the growth of human hypertrophic scar fibroblasts by regulating Smad2 expression. [PDF]

Mol Med Rep
Shi Y, Wang L, Yu P, Liu Y, Chen W.
europepmc   +1 more source

MicroRNA‑877 is downregulated in cervical cancer and directly targets MACC1 to inhibit cell proliferation and invasion

, 2019
Fanxu Meng, Jian Ou, Jinyu Liu, Xindi Li, Yanli Meng, Ling Yan, Ping Deng, Baosheng Sun   +7 more
openalex   +2 more sources

MicroRNA-29 (miR-29); c-Myc (MYC); histone deacetylase 3 (HDAC3); enhancer of zeste homolog 2 (EZH2) [PDF]

, 2012

openalex   +1 more source

Cerebrospinal Fluid from Restless Legs Syndrome Patients Reduces Iron Uptake in Blood–Brain Barrier Endothelial Cells by Disrupting the Regulation of Transferrin Receptors

Annals of Neurology, EarlyView.
Model figure of BBBECs TfR1 regulation in control and RLS: Graphical representation of TfR1 regulation in ECs by IRPs and representing it can be dysregulated by miR‐124‐3p in ECs of RLS. FPN1, ferroportin; BBBEC, blood‐brain barrier endothelial cells; IRP, iron regulatory proytein1/2; TfR1, Transferrin receptor; IRE, Iron responsive elements; Tf ...
Kondaiah Palsa, Aurosman Pappus Sahu, David B. Rye, Lynn Marie Trotti, Irina A. Elcheva, Vladimir S. Spiegelman, James R. Connor   +6 more
wiley   +1 more source

[Retracted] Roles of the SNHG7/microRNA‑9‑5p/DPP4 ceRNA network in the growth and ¹³¹I resistance of thyroid carcinoma cells through PI3K/Akt activation. [PDF]

Oncol Rep
Chen W, Yu J, Xie R, Zhou T, Xiong C, Zhang S, Zhong M.   +6 more
europepmc   +1 more source

Serum extracellular vesicle microRNA dysregulation and childhood trauma in adolescents with major depressive disorder

, 2022
Liuyi Ran, Yiting Kong, Jiao-Jiao Xiang, Zeng Qi, Chen‐Yu Zhang, Lei Shi, Haitang Qiu, Chuan Liu, Lin-li Wu, Yalan Li, Jianmei Chen, Ming Ai, Wo Wang, Li Kuang   +13 more
openalex   +2 more sources

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Circulating non-canonical small non-coding RNAs as novel diagnostic biomarkers for tuberculosis

Microbiology Spectrum
Ping Yang, Shoubin Zhan, Yi Zhu, Zhenbiao Yu, Xiaoshan Zhang, Ning Dong, Shiting Xie, Renjie Miao, Han Shen, Xuemei Wang, Chenyu Zhang, Hong Yan   +11 more
doaj   +1 more source

A shift of paradigm, emerging role of miRNAs as therapeutic targets for complex disease. [PDF]

Mol Ther Nucleic Acids
Altieri A, Mastricci A, Panella R.
europepmc   +1 more source