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MicroRNA and implantation

Fertility and Sterility, 2014
We provide a review of microRNA (miRNA) related to human implantation which shows the potential diagnostic role of miRNAs in impaired endometrial receptivity, altered embryo development, implantation failure after assisted reproduction technology, and in ectopic pregnancy and pregnancies of unknown location. MicroRNAs may be emerging diagnostic markers
Daniela, Galliano, Antonio, Pellicer
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microRNAs in Inflammation

International Reviews of Immunology, 2009
microRNAs are small noncoding RNAs that regulate protein-coding genes via posttranscriptional repression. Most protein-coding genes are subjected to microRNA-mediated regulation, making the potential effect of these small molecules on regulatory networks enormous.
Enikö, Sonkoly, Andor, Pivarcsi
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microRNA and Epilepsy

2015
Epilepsy is a common, serious neurological disease characterized by recurring seizures. Such abnormal, excessive synchronous firing of neurons arises in part because of imbalances in excitation and inhibition in the brain. The process of epileptogenesis, during which the normal brain is transformed after injury to one capable of generating spontaneous ...
Cristina R, Reschke, David C, Henshall
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microRNAs in neurodegeneration

Current Opinion in Neurobiology, 2008
microRNAs (miRNAs) act as post-transcriptional regulators of gene expression in diverse cellular and developmental processes. Many miRNAs are expressed specifically in the central nervous system, where they have roles in differentiation, neuronal survival, and potentially also in plasticity and learning.
Natascha, Bushati, Stephen M, Cohen
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MicroRNAs in Atherosclerosis

Journal of Vascular Research, 2014
Micro-ribonucleic acids (miRNAs) are a class of endogenous non-coding ribonucleic acids that regulate gene expression. MiRNAs have been shown to act as key regulators in the vascular system, with wide-ranging physio-pathological effects. Atherosclerotic disease is a leading cause of morbidity and mortality worldwide.
Ali A, Hosin   +4 more
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Cardioprotective MicroRNAs

Pediatric Cardiology, 2011
MicroRNAs (miRNAs) are involved in almost every aspect of a mammalian cell's functionality, from stem cell differentiation to aging and pathogenesis; however, their role in immediate cell signaling is less defined. This has been recently demonstrated by the rapid increase or decrease of miR-21's abundance within minutes of activation or inhibition of ...
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MicroRNAs and cancer

Seminars in Cancer Biology, 2003
The general basis of cancer is the loss of cell identity and inappropriate proliferation of cells. Classically, a universal paradigm in oncogenesis is the accumulation of mutations in the open reading frames of protein-encoding oncogenes and tumor suppressors.
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microRNA and Allergy

2015
Allergy is a common hypersensitivity disorder of the immune system, which, along with other factors, is also subjected to regulation by microRNAs. The most common allergic diseases are allergic rhinitis, asthma, atopic dermatitis, and food allergy, which all are multifactorial and very heterogeneous conditions, highlighting the need for more ...
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MicroRNAs in the hypothalamus

Best Practice & Research Clinical Endocrinology & Metabolism, 2016
The brain is considered a major site for microRNA (miRNA) expression; as evidenced by several studies reporting microarray data of different brain substructures. The hypothalamus is among the brain regions that plays a crucial role in integrating signals from other brain nuclei as well as environmental, hormonal, metabolic and neuronal signals from the
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MicroRNAs as oncogenes

Current Opinion in Genetics & Development, 2006
MicroRNAs (miRNAs) are a class of non-coding RNAs that function as endogenous triggers of the RNA interference pathway. Originally discovered in Caenorhabditis elegans, this group of tiny RNAs has moved to the forefront of biology. With over 300 miRNA genes identified in the human genome, and a plethora of predicted mRNA targets, it is believed that ...
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