Results 181 to 190 of about 164,070 (265)

Unveiling the molecular profile of adenosquamous gallbladder carcinoma: characterization of a Caucasian cohort

Histopathology, EarlyView.
GBASCs are MMRp tumours, exhibiting minimal HER2 overexpression and elevated PD‐L1 expression compared to adenocarcinomas. Especially in metastatic and TP53‐wild type tumours, GBASCs can express CLDN18, albeit limited to the glandular component. Their genomic profile resembles that of adenocarcinomas with an enrichment in alterations on PIK3CA, PTEN ...
Jessica Gasparello, Valentina Angerilli, Mario Domenico Rizzato, Edoardo Maffii, Carlotta Ceccon, Matilde Callegarin, Marianna Sabbadin, Monia Niero, Luisa Toffolatti, Francesca Bergamo, Paola Parente, Luca Mastracci, Federica Grillo, Alessandro Vanoli, Paola Mattiolo, Claudio Luchini, Angelo Paolo Dei Tos, Umberto Cillo, Giacomo Zanus, Sara Lonardi, Matteo Fassan   +20 more
wiley   +1 more source

Mutations Targeted by Nous-209 Immunotherapy Occur Early in Lynch Syndrome Carriers' Precancer Lesions with Microsatellite Instability. [PDF]

Cancer Prev Res (Phila)
Micarelli E, De Marco L, Spaggiari P, D'Alise AM, Dal Buono A, Menini M, Giatti V, D'Aprano A, Scarselli E, Hassan C, Repici A.   +10 more
europepmc   +1 more source

NFE2L2‐mutated urothelial carcinomas frequently show concomitant myxoid and squamous features and have high PD‐L1 expression

Histopathology, EarlyView.
Aims NFE2L2 encodes the transcription factor, NRF2, which is a regulator of cellular oxidative stress responses and metabolic homeostasis. NFE2L2 alterations are implicated in multiple cancers, with significant study in thoracic oncology, with an adverse prognosis, aggressive behaviour, metabolic reprogramming and diminished responses to chemotherapy ...
Dane Wuori, Alexander Guzzetta, Melissa Y. Tjota, Peng Wang, Tatjana Antic, Jung Woo Kwon   +5 more
wiley   +1 more source

An Algorithmic Approach for Quantitative Determination of Microsatellite Status in NGS-Based Cancer Diagnostics. [PDF]

Cancers (Basel)
Männlein J, Sterlacci W.
europepmc   +1 more source

Genes, fish and fisheries: translating science into policy

Journal of Fish Biology, EarlyView.
Abstract The 2024 Annual Symposium of the Fisheries Society of the British Isles reviewed the burgeoning impact of ‘omics’ technologies on fish ecology, management and forecasting. As with life sciences more generally, major advances in speed, cost‐effectiveness and breadth of applications in ‘omics’ has had profound societal and environmental impacts.
Gary R. Carvalho
wiley   +1 more source

Analysis of microsatellite instability intensity in single-cell resolution with scMnT reveals tumor heterogeneity in colorectal cancer. [PDF]

Brief Bioinform
Park G, Park J.
europepmc   +1 more source

Sequence capture analysis determines spatial and temporal stock contributions to a mixed coastal anadromous fishery

Journal of Fish Biology, EarlyView.
Abstract Employing a citizen science model of partnerships with recreational and commercial fishers, we collected 5298 fin‐clip samples of striped bass Morone saxatilis over a 2‐year period and a broad geographic area that encompassed a majority of the species migratory range.
Kristopher J. Wojtusik, David L. Berlinsky, Linas W. Kenter, Adrienne I. Kovach   +3 more
wiley   +1 more source

A single nucleotide polymorphism genotyping panel for efficient genetic stock identification of the Teno river Atlantic salmon (Salmo salar) population complex

Journal of Fish Biology, EarlyView.
Abstract A new single nucleotide polymorphism (SNP) panel for genetic stock identification in the Teno river Atlantic salmon, Salmo salar L., fishery was developed, with a view to improving on an existing microsatellite panel. Twenty‐two genetically differentiated reporting units were proposed based on population genetic analyses of 1212 individuals ...
Helena Johansson, Jaakko Erkinaro, Morten Falkegård, Anders Foldvik, Panu Orell, Craig R. Primmer, Victoria L. Pritchard   +6 more
wiley   +1 more source

Evidence of <i>in situ</i> hybridization between trans-Andean tamarin species (Callitrichidae<i>, Oedipomidas</i>) in northwestern Colombia. [PDF]

J Mammal
Pérez-Estrada AM, Soto-Calderón ID.
europepmc   +1 more source

DNA extracted from boiled archival fish bones yields high‐quality whole‐genome sequencing data

Journal of Fish Biology, EarlyView.
Abstract Archival samples provide a unique source of organismal DNA, offering the potential to extend the temporal scale of genetic studies by decades to centuries. Fish hard structures, such as otoliths and scales, serve as records for fish collected during fisheries monitoring across a large spatiotemporal scale.
Jingyao Niu, Anti Vasemägi, María‐Eugenia López, Lilian Pukk, Magnus Huss, Anna Gårdmark   +5 more
wiley   +1 more source