Results 201 to 210 of about 269,745 (308)

Treating microsatellite unstable metastatic parathyroid carcinoma with anti-PD1 therapy. [PDF]

JCEM Case Rep
Amir-Kabirian B, AlRubaye R, Cadle B, Mais D, Sibai Z, Redman R.   +5 more
europepmc   +1 more source

Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin, Ayse Basak Engin, Atilla Engin   +2 more
wiley   +1 more source

A previously low prevalence Plasmodium falciparum clone expands in an outbreak in the Pacific Coast of South America. [PDF]

BMC Infect Dis
Cartagenova A, Zapata-Berrones K, Boboy J, Cuero W, Neafsey DE, Early AM, Sáenz FE.   +6 more
europepmc   +1 more source

Incidental Colorectal Adenomas in Adolescents: Clinical Management, Genetic Evaluation, and Surveillance

Journal of Gastroenterology and Hepatology, EarlyView.
Adolescents with incidental colorectal adenomas require age‐conscious management balancing referral for genetic counseling with evidence‐based surveillance. This narrative review proposes a pragmatic clinical algorithm integrating adenoma characteristics, hereditary risk assessment, and guideline‐concordant follow‐up to support individualized ...
Brett J. Hoskins, Shlomi Cohen, Colleen B. Flahive, Isabel Rojas, Aparajita Singh, Thomas M. Attard   +5 more
wiley   +1 more source

Multi‐generation analysis of whether local or genetically mixed populations perform best in restoration plantings

Restoration Ecology, EarlyView.
Abstract Introduction Proper selection of genetic material is critical for restoring populations, with local seed often selected to maximize local adaptation. But if local populations are small, inbred, or maladapted, then including genotypes from various populations may enhance population growth and long‐term adaptation.
Regan L. Cross, Christopher G. Eckert
wiley   +1 more source

Clinical and immunological implications of lymphocyte-activation gene 3 expression in metastatic colorectal cancer. [PDF]

Cancer Immunol Immunother
Huang YH, Wu SY, Lee CT, Chung BS, Lin PC, Chan RH, Chen PC, Lin BW, Shen MR, Chen SH, Yeh YM.   +10 more
europepmc   +1 more source

Return of the ants: investigating temporal and spatial patterns of ant colonization in unsealed schoolyards

Restoration Ecology, EarlyView.
Abstract Introduction Urban soil unsealing, the removal of impervious surface layers, is increasingly promoted as a habitat restoration strategy to enhance ecosystem resilience in cities. Yet, its potential to support soil biodiversity from the onset remains underexplored.
Robin Chevrel, Alan Vergnes, Pierre Jay‐Robert, Bernard Kaufmann, Louise Eydoux   +4 more
wiley   +1 more source

The Keynote-177 Randomized Controlled Trial of First-line PD-1 Blockade for Microsatellite-High or Mismatch Repair-Deficient Advanced Colorectal Cancer: Potential Consequences of the Cross-Over Trial Design and Related Issues. [PDF]

Cancer Med
Gerritse SL, van Meerten E, Duits AJ, Schnog JB.   +3 more
europepmc   +1 more source

Comparative Response of Canine and Human Osteosarcoma Tumour Cell Lines to Molecularly Targeted Anticancer Agents at Clinically Relevant Exposures With Analysis of Genomic Biomarkers

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Osteosarcoma (OSA) is a primary bone tumour occurring in children but is also prevalent in large breed dogs. Canine OSA (cOSA) has long been viewed as analogous to human OSA (hOSA) with cOSA serving as a surrogate for development of therapeutic approaches to treat the rarer human form.
Daniel L. Gustafson, Kala A. Early, Maritza A. Morales, Klaudia A. Poplawski, Sunetra Das, Dawn L. Duval   +5 more
wiley   +1 more source