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Of Microbes and Microsatellites
Cancer Immunology Research, 2018Abstract A ubiquitous oral cavity microbe, Fusobacterium nucleatum, is increasingly being implicated in colorectal cancer pathogenesis. An article in this issue elucidates the differential association of F. nucleatum with tumor-infiltrating lymphocytes depending on microsatellite instability status.
Chloe E, Atreya, Alan P, Venook
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Trends in Ecology & Evolution, 1993
Many evolutionary studies, particularly kinship studies, have been limited by the availability of segregating genetic marker loci. Microsatellites promise to alleviate these problems. Microsatellite loci are segments of DNA with very short sequence motifs repeated in tandem; their often numerous alleles differ in the number of these repeat units.
D C, Queller +2 more
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Many evolutionary studies, particularly kinship studies, have been limited by the availability of segregating genetic marker loci. Microsatellites promise to alleviate these problems. Microsatellite loci are segments of DNA with very short sequence motifs repeated in tandem; their often numerous alleles differ in the number of these repeat units.
D C, Queller +2 more
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Journal of Computational Biology, 2006
Genotype calling procedures vary from laboratory to laboratory for many microsatellite markers. Even within the same laboratory, application of different experimental protocols often leads to ambiguities. The impact of these ambiguities ranges from irksome to devastating.
Angela P. Presson +3 more
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Genotype calling procedures vary from laboratory to laboratory for many microsatellite markers. Even within the same laboratory, application of different experimental protocols often leads to ambiguities. The impact of these ambiguities ranges from irksome to devastating.
Angela P. Presson +3 more
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Microsatellites for Microbiologists
2012Microsatellites are repeating sequences of 2-6base pairs of DNA. Currently, they are used as molecular markers in many organisms, specifically in genetic studies analyzing kinship and population structure. In addition, they can be used to study gene duplication and/or deletion.
Sweet MJ, Scriven LA, Singleton I
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Cytogenetic and Genome Research, 2001
Unlike aneuploidy, considered to be the cardinal feature of malignant tumors ever since the chromosomal analysis of neoplastic cells became technically feasible, a second pathway toward malignancy has emerged over the past decade that is not characterized by gross aneuploidy but, instead, by inactivation of the DNA mismatch repair system, leading to a ...
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Unlike aneuploidy, considered to be the cardinal feature of malignant tumors ever since the chromosomal analysis of neoplastic cells became technically feasible, a second pathway toward malignancy has emerged over the past decade that is not characterized by gross aneuploidy but, instead, by inactivation of the DNA mismatch repair system, leading to a ...
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A new bovine dinucleotide repeat microsatellite: microsatellite INRA 18
Animal Genetics, 1993An Anonymous clone containing a (TG)11 Microsatellites was isolated from a bovine genomic Sau3A size selected (approx.500pb) pGEM-4-Z library by hybridization to poly (dC-dT). Primers for polymerase chai reaction (PCR) were designed to amplify the region containing this microsatellite.
Moazami-Goudarzi, Katayoun +3 more
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A new bovine dinucleotide repeat microsatellite: microsatellite INRA 30
Animal Genetics, 1993"Chantier qualité spécifique "Auteurs Externes" département de Génétique animale : uniquement liaison auteur au référentiel HR-Access " ; International ...
Ciampolini, R. +3 more
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Mutational Dynamics of Microsatellites
Molecular Biotechnology, 2009Microsatellites are a ubiquitous class of simple repetitive DNA sequences, which are widespread in both eukaryotic and prokaryotic genomes. The use of microsatellites as polymorphic DNA markers has considerably increased both in the number of studies and in the number of organisms, primarily for genetic mapping, studying genomic instability in cancer ...
Atul, Bhargava, F F, Fuentes
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