Results 221 to 230 of about 197,028 (259)

Do Habitat Restoration Efforts and the Associated Releases of Hatchery‐Reared Fish Affect the Genetic Diversity and Integrity of Native Brown Trout Populations?

open access: yesFisheries Management and Ecology, EarlyView.
ABSTRACT Habitat restoration may protect brown trout (Salmo trutta) populations from loss of genetic diversity by increasing environmental carrying capacity and, consequently, population size. However, the accompanying release of hatchery‐reared fish may threaten the genetic integrity of native populations through introgression.
Noor Alwash   +6 more
wiley   +1 more source

NFE2L2‐mutated urothelial carcinomas frequently show concomitant myxoid and squamous features and have high PD‐L1 expression

open access: yesHistopathology, EarlyView.
Aims NFE2L2 encodes the transcription factor, NRF2, which is a regulator of cellular oxidative stress responses and metabolic homeostasis. NFE2L2 alterations are implicated in multiple cancers, with significant study in thoracic oncology, with an adverse prognosis, aggressive behaviour, metabolic reprogramming and diminished responses to chemotherapy ...
Dane Wuori   +5 more
wiley   +1 more source

Poorly differentiated lung adenocarcinomas with concurrent ALK and CD30 expression: a diagnostic pitfall mimicking ALK‐positive anaplastic large‐cell lymphoma

open access: yesHistopathology, EarlyView.
Poorly differentiated lung adenocarcinomas with concurrent anaplastic lymphoma kinase (ALK) and CD30 expression closely mimic ALK‐positive anaplastic large‐cell lymphoma, creating a significant diagnostic pitfall. Accurate classification requires comprehensive integration of clinical, radiologic, morphologic, immunophenotypic and molecular findings ...
Jietian Jin   +6 more
wiley   +1 more source

Population genetic analysis of the endangered Mottled Duskywing butterfly (Erynnis martialis) informs species reintroduction

open access: yesInsect Conservation and Diversity, EarlyView.
Mottled Duskywing (Erynnis martialis) populations had moderate levels of genetic diversity at microsatellites with expected heterozygosity ranging from 0.43 to 0.58, and populations more than 10 km apart were differentiated from one another. Weak patterns of isolation by distance and low effective population sizes suggest that all but the largest ...
Shayla L. Kroeze   +6 more
wiley   +1 more source

Characterizing Runs of Homozygosity and Inbreeding in American Mink Using SNP Data and Pedigree Information

open access: yesJournal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Inbreeding increases the likelihood of deleterious recessive alleles becoming homozygous and consequently affecting economically important traits. Runs of homozygosity (ROH), the continuous homozygous segments of the genome and the higher than expected homozygosity (HOM) are genomic indicators of inbreeding, quantified as FROH and FHOM ...
Persia Carol Thapa   +4 more
wiley   +1 more source

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