Results 41 to 50 of about 109,422 (246)

Multi-Objective optimization for stable and efficient cargo transportation of partial space elevator

Defence Technology
This paper proposed a new libration decoupling analytical speed function (LD-ASF) in lieu of the classic analytical speed function to control the climber's speed along a partial space elevator to improve libration stability in cargo transportation.
Gefei Shi, Zheng H. Zhu
doaj   +1 more source

Infestation Pattern and Population Dynamics of the Tropical Bed Bug, Cimex hemipterus (F.) (Hemiptera: Cimicidae) Based on Novel Microsatellites and mtDNA Markers

Insects, 2020
The tropical bed bug, Cimex hemipterus (F.), has now emerged as an important public health pest in the tropics. Despite its alarming infestation rate, the information on its population genetics remains scarce. Here, we described the infestation structure
Wan Nur Fatanah Wan Mohammad, Li-Shen Soh, Wan Nurainie Wan Ismail, G. Veera Singham   +3 more
doaj   +1 more source

Hypofractionated Radiotherapy Induces ISG15+MHC‐I+ Neutrophils to Augment Anti‐Tumor Immunity and Prime Immune Checkpoint Blockade Responses in Rectal Cancer

Advanced Science, EarlyView.
ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu, Haihong Wang, Mingjie Li, Qian Xu, Linlin Zheng, Chaoqun Han, Zhenwei Zou, Jinghua Ren, Xiaorong Dong, Peng Zhang, Kaixiong Tao, Zhenyu Lin, Tao Zhang   +12 more
wiley   +1 more source

His‐MMDM: Multi‐Domain and Multi‐Omics Translation of Histopathological Images with Diffusion Models

Advanced Science, EarlyView.
His‐MMDM is a diffusion model‐based framework for scalable multi‐domain and multi‐omics translation of histopathological images, enabling tasks from virtual staining, cross‐tumor knowledge transfer, and omics‐guided image editing. ABSTRACT Generative AI (GenAI) has advanced computational pathology through various image translation models.
Zhongxiao Li, Tianqi Su, Bin Zhang, Wenkai Han, Sibin Zhang, Guiyin Sun, Yuwei Cong, Xin Chen, Jiping Qi, Yujie Wang, Shiguang Zhao, Hongxue Meng, Peng Liang, Xin Gao   +13 more
wiley   +1 more source

Genetic Diversity and Population Structure of Largefin Longbarbel Catfish (Hemibagrus macropterus) Inferred by mtDNA and Microsatellite DNA Markers

Animals
The largefin longbarbel catfish (Hemibagrus macropterus), a freshwater species endemic to China with fundamental economic importance, requires investigation into its genetic structure for effective management.
Yanling Hou, Huan Ye, Huamei Yue, Junyi Li, Ling Huang, Ziling Qu, Rui Ruan, Danqing Lin, Zhiqiang Liang, Yong Xie, Chuangju Li   +10 more
doaj   +1 more source

Diversidade genética e eficiência de DNA microssatélites para o controle genealógico da raça Nelore Genetic diversity and efficiency of DNA microsatellites for genealogic control in Nelore breed

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2007
Foram estimados na raça Nelore a variabilidade genética e os valores de determinação de paternidade usando-se 11 marcadores microssatélites do painel ISAG/FAO.
T.X. Carneiro, E.C. Gonçalves, M.P.C. Schneider, A. Silva   +3 more
doaj   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

A hybrid zone of the genus Ctenomys: a case study in southern Brazil

Genetics and Molecular Biology, 2012
We describe variation at microsatellite loci and the chromosomal polymorphisms of a hybrid population, and hybridizing populations of Ctenomys minutus (the minor tuco-tuco) from the coastal plain of Rio Grande do Sul, southern Brazil.
Camila S. Castilho, Adriana Gava, Thales R.O. de Freitas   +2 more
doaj   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Genetic relationships among twelve Chinese indigenous goat populations based on microsatellite analysis

Genetics Selection Evolution, 2002
Twelve Chinese indigenous goat populations were genotyped for twenty-six microsatellite markers recommended by the EU Sheep and Goat Biodiversity Project. A total of 452 goats were tested.
Li Shi-Jun, Zhu Meng-Jin, Chen Shi-Lin, Fan Bin, Yu Mei, Liu Bang, Wei Hong, Bian Ci, Wang Hai-Sheng, Zhao Shu-Hong, Li Meng-Hua, Xiong Tong-An, Li Kui   +12 more
doaj   +1 more source