Results 131 to 140 of about 50,169 (235)
The Role of Microsatellite Instability in Endometrial Hyperplasia and Risk of Carcinoma Development. [PDF]
Mollova-Kyosebekirova A +5 more
europepmc +1 more source
What's new? CATCH is a prospective precision oncology registry trial that harnesses whole‐genome/exome‐ and RNA‐sequencing to enable actionable biomarker detection in metastatic breast cancer patients of any subtype. The data of the first 412 consecutive patients with completed follow‐up in this real‐world, single‐center patient cohort provide robust ...
Mario Hlevnjak +31 more
wiley +1 more source
Analysis of DNA mismatch repair and microsatellite instability in molecular typing of endometrial carcinoma. [PDF]
Li NM, Cheng HP, Zhou P, Li XH.
europepmc +1 more source
ABSTRACT Purpose To assess the effectiveness and safety of hepatic arterial infusion chemotherapy (HAIC) in patients with mismatch repair proficient (pMMR)/microsatellite stable (MSS) colorectal cancer liver metastases (CRLM) who are resistant to standard treatments.
Yawei Li +5 more
wiley +1 more source
Improving the performance of polymerase chain reaction for microsatellite instability testing in endometrial cancer. [PDF]
Mendiola M +11 more
europepmc +1 more source
ABSTRACT In colorectal cancer (CRC), circulating tumour cells (CTCs) employ genetic alterations to dodge the body's immune system. These alterations occur in specific “driver” genes, including KRAS, BRAF, p53, MYC, APC and PTEN. Changes in these genes can control how the tumour interacts with the immune system and influence the expression of immune ...
Sharmin Aktar +5 more
wiley +1 more source
ABSTRACT Introduction Centrosome clustering is a cancer‐specific adaptation that allows cells with centrosome amplification to evade mitotic catastrophe and has emerged as a potential therapeutic target. We analyzed the prognostic role of several molecules related to centrosome clustering and found that Kinesin Family Member C1 (KIFC1) was strongly ...
Yoshinori Nakano +14 more
wiley +1 more source
Diagnostic Challenges and Clinical Implications of Microsatellite Instability/Mismatch Repair Deficiency in Solid Tumors. [PDF]
Kwak Y, Bae JM, Lee HS.
europepmc +1 more source

