Results 131 to 140 of about 55,423 (289)

A Highly Sensitive Pan-Cancer Test for Microsatellite Instability [PDF]

, 2023
Jeffery W. Bacher, Eshwar Udho, Ethan E. Strauss, Irina Vyazunova, Steven Gallinger, Daniel D. Buchanan, Rish K. Pai, Allyson Templeton, Douglas R. Storts, James R. Eshleman, Richard B. Halberg   +10 more
openalex   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Near-complete association between microsatellite instability and abnormal immunostaining of the mismatch repair proteins hMSH2, hMSH6, hMLH1 and hPMS2 and involvement of hMSH6 in sporadic and hereditary colorectal cancers [PDF]

, 2001
Jens Plaschke, Stefan Krüger, Stephan Haas, Steffen Pistorius, Hans-D. Saeger, Hans K. Schackert   +5 more
openalex   +1 more source

Figure S8 from Real-world Validation of TMB and Microsatellite Instability as Predictive Biomarkers of Immune Checkpoint Inhibitor Effectiveness in Advanced Gastroesophageal Cancer

, 2023
Ryon P. Graf, Virginia Fisher, James Creeden, Alexa B. Schrock, Jeffrey S. Ross, Halla Nimeiri, Geoffrey R. Oxnard, Samuel J. Klempner   +7 more
openalex   +1 more source

Systematic review of machine learning-based radiomics approach for predicting microsatellite instability status in colorectal cancer [PDF]

, 2023
Qiang Wang, Jianhua Xu, Anrong Wang, Yi Chen, Tian Wang, Danyu Chen, Jiaxing Zhang, Torkel B. Brismar   +7 more
openalex   +1 more source

Scat DNA Applications for Low‐Density Carnivore Survey: Techniques, Efficiency and Future Directions

Mammal Review, Volume 56, Issue 1, March 2026.
We reviewed 338 studies encompassing mostly Felidae, Canidae and Mustelidae species throughout the world, confirming scat DNA as a reliable genetic source for many applications. The findings here offer guidance for future studies on low‐density carnivores, helping to design cost‐effective research and improving data quality for conservation efforts ...
Marina Elisa de Oliveira, Fernando Gonçalves, Pedro M. Galetti Jr   +2 more
wiley   +1 more source

A comparison by mismatch repair status of real‐world characteristics and outcomes in patients with stage II/III rectal cancer in the Netherlands

International Journal of Cancer, Volume 158, Issue 4, Page 963-976, 15 February 2026.
What's new? Mismatch repair deficiency (dMMR) in rectal cancer is rare, and knowledge about tumor biological behavior, response to treatment, and clinical outcomes in this subset of patients is limited. This nationwide cohort study including 182 patients with dMMR rectal cancer found that they were younger and had more poorly differentiated tumors ...
Renee A. Lunenberg, Ingrid A. Franken, Frederieke H. van der Baan, Femke P. C. Sijtsma, Geraldine R. Vink, Manon N. G. J. A. Braat, Leon M. G. Moons, Miangela M. Lacle, Marloes A. G. Elferink, Susan Boklage, Martijn P. W. Intven, Jamie Garside, Miriam Koopman, Rob van Wuijtswinkel, Jeanine M. L. Roodhart   +14 more
wiley   +1 more source

Meta-analysis of microsatellite instability in relation to clinicopathological characteristics and overall survival in gastric cancer

, 2017
Karol Połom, Luigi Marano, Daniele Marrelli, Raffaele De Luca, Giandomenico Roviello, Vinno Savelli, Patrick Tan, Franco Roviello   +7 more
openalex   +2 more sources

Independent Tissue-Based Biomarkers in Endometrioid Endometrial Cancer: Tumor Budding in Microsatellite Instability and WHO Grading in Copy-Number-Low Patients [PDF]

, 2023
Fabian Stögbauer, Barbara Geß, Christine Brambs, Manuela Lautizi, Tim Kacprowski, Iordanis Ourailidis, Holger Bronger, Marion Kiechle, Aurelia Noske, Gisela Keller, Moritz Jesinghaus, Christopher Poremba, Wilko Weichert, Melanie Boxberg   +13 more
openalex   +1 more source

Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Emerging studies indicate that microbes are present in tumor cells and immune cells. Intratumoral microbiota (ITM) constitute an important component of the tumor immune microenvironment (TIME) and have an important impact on tumor progression and treatment. Objective Through the general elaboration of ITM represented by bacteria and
Fengxue Li, Lili Qiao, Xinquan Liang, Yingying Zhang, Ning Liang, Jian Xie, Guodong Deng, Yuying Hao, Pingping Hu, Xue Wu, Fangjie Ding, Can Feng, Yiming Mu, Jiandong Zhang   +13 more
wiley   +1 more source