Results 131 to 140 of about 50,169 (235)

The Role of Microsatellite Instability in Endometrial Hyperplasia and Risk of Carcinoma Development. [PDF]

open access: yesBiomedicines
Mollova-Kyosebekirova A   +5 more
europepmc   +1 more source

Delivering precision oncology in metastatic breast cancer: Clinical impact of comprehensive genomic profiling—The CATCH experience

open access: yesInternational Journal of Cancer, Volume 158, Issue 6, Page 1675-1689, 15 March 2026.
What's new? CATCH is a prospective precision oncology registry trial that harnesses whole‐genome/exome‐ and RNA‐sequencing to enable actionable biomarker detection in metastatic breast cancer patients of any subtype. The data of the first 412 consecutive patients with completed follow‐up in this real‐world, single‐center patient cohort provide robust ...
Mario Hlevnjak   +31 more
wiley   +1 more source

The Efficacy and Safety of Hepatic Arterial Infusion Chemotherapy for Mismatch Repair Proficient (pMMR)/Microsatellite Stable (MSS) Colorectal Cancer Liver Metastases (CRLM)

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Purpose To assess the effectiveness and safety of hepatic arterial infusion chemotherapy (HAIC) in patients with mismatch repair proficient (pMMR)/microsatellite stable (MSS) colorectal cancer liver metastases (CRLM) who are resistant to standard treatments.
Yawei Li   +5 more
wiley   +1 more source

Improving the performance of polymerase chain reaction for microsatellite instability testing in endometrial cancer. [PDF]

open access: yesSci Rep
Mendiola M   +11 more
europepmc   +1 more source

Genetic Alterations Involved in Immune Escape Mechanisms of Circulating Tumour Cells in Colorectal Carcinogenesis

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT In colorectal cancer (CRC), circulating tumour cells (CTCs) employ genetic alterations to dodge the body's immune system. These alterations occur in specific “driver” genes, including KRAS, BRAF, p53, MYC, APC and PTEN. Changes in these genes can control how the tumour interacts with the immune system and influence the expression of immune ...
Sharmin Aktar   +5 more
wiley   +1 more source

KIFC1 is Associated With Sarcomatoid Differentiation, Immune Response, and a Poor Prognosis in Clear Cell Renal Cell Carcinoma

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Introduction Centrosome clustering is a cancer‐specific adaptation that allows cells with centrosome amplification to evade mitotic catastrophe and has emerged as a potential therapeutic target. We analyzed the prognostic role of several molecules related to centrosome clustering and found that Kinesin Family Member C1 (KIFC1) was strongly ...
Yoshinori Nakano   +14 more
wiley   +1 more source

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