Results 181 to 190 of about 55,423 (289)

CYP4X1/sEH‐Dependent Endocannabinoid Metabolism Drives Fibroblast‐Mediated Immunosuppression to Limit Immunotherapy in Colon Cancer

Advanced Science, Volume 13, Issue 5, 27 January 2026.
A proposed mechanism to explain the role of CYP4X1/sEH‐14,15‐EET‐EA system in colon cancer immune escape. 14,15‐EET‐EA, 14,15‐epoxyeicosatrienoic acid‐ethanolamide; sEH, soluble epoxide hydrolase; CYP4X1, cytochrome P450 4X1; GPR119, G‐protein coupled receptor 119; EGFR, epidermal growth factor receptor; Gs, Gαs subunit; cAMP, cyclic adenosine ...
Min Mo, Xuewei Chen, Yanzhuo Liu, Chenlong Wang, Xuehan Chen, Nan Zhang, Nan He, Ying Li, Jingyi Wang, Honglei Chen, Jing Yang   +10 more
wiley   +1 more source

Prediction of Microsatellite Instability in Colorectal Cancer Using Two Internally Validated Radiomic Models. [PDF]

Tomography
Galluzzo A, Danti G, Calistri L, Cozzi D, Lavacchi D, Rossini D, Antonuzzo L, Paolucci S, Castiglione F, Messerini L, Cianchi F, Miele V.   +11 more
europepmc   +1 more source

Impact of BRAF mutation and microsatellite instability on the pattern of metastatic spread and prognosis in metastatic colorectal cancer

, 2011
Ben Tran, Scott Kopetz, Jeanne Tie, Peter Gibbs, Zhi‐Qin Jiang, Christopher H. Lieu, Atin Agarwal, Dipen M. Maru, Oliver M. Sieber, Jayesh Desai   +9 more
openalex   +1 more source

The Role of Microsatellite Instability in Gastric Low- and High-Grade Lymphoma Development [PDF]

, 2000
Petr Starostik, Andreas Greiner, Stephan Schwarz, Jochen Patzner, Anja Schultz, H. K. Müller-Hermelink   +5 more
openalex   +1 more source

Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome

Advanced Science, Volume 13, Issue 6, 30 January 2026.
This study introduces a new hypothesis: exons, introns, and intergenic segments are non‐random projections of the functional layers of 3D structure of chromatin packing domains. Evidence is presented that this “geometric code” may encode volumetric structure, reconciling epigenetic patterns, correlates with oncogenic mutations, acting as a potential ...
Luay M. Almassalha, Kyle L. MacQuarrie, Marcelo Carignano, Cody L. Dunton, Ruyi Gong, Joe Ibarra, Lucas M. Carter, Wing Shun Li, Rikkert Nap, Parambir S. Dulai, Igal Szleifer, Vadim Backman   +11 more
wiley   +1 more source

Ensemble learning for predicting microsatellite instability in colorectal cancer using pretreatment colonoscopy images and clinical data. [PDF]

Front Oncol
You J, Zhang S, Zhang J, Chen Y, Zhang M, Zhou C, Jiang B.   +6 more
europepmc   +1 more source

Combined Analysis of COX-2 and p53 Expressions Reveals Synergistic Inverse Correlations with Microsatellite Instability and CpG Island Methylator Phenotype in Colorectal Cancer

, 2006
Shuji Ogino, Mohan Brahmandam, Takako Kawasaki, Gregory J. Kirkner, Massimo Loda, Charles S. Fuchs   +5 more
openalex   +1 more source

Chronic ER Stress Triggers Cell‐Surface Chaperones as the Therapeutic Targets of CAR Cells in Acute Myeloid Leukemia

Advanced Science, Volume 13, Issue 5, 27 January 2026.
Acute myeloid leukemia (AML) remains a therapeutic challenge due to its heterogeneity and limited targets. Here, multi‐omics analyses are utilized, and it is revealed that AML cells, particularly the FLT3‐ITD+ subtype, undergo chaperone‐mediated ER stress, inducing surface translocation of ER chaperones.
Yimin Zhou, Zhenfei Zhong, Peng Hu, Weigang Wang, Ying Song, Na Yang, Fangyan He, Yajie Li, Qi Sa, Yanmei Yang, Qinmiao Sun, Tonghua Yang, Beibei Zhang, Dahua Chen   +13 more
wiley   +1 more source

A two-stage deep learning prediction system for colon cancer microsatellite instability status using CT images. [PDF]

Front Oncol
Cui S, Xiong X, Yang X, He J, Shen T.
europepmc   +1 more source

Improved Detection of Microsatellite Instability in Early Colorectal Lesions

, 2015
Jeffery W. Bacher, Chelsie K. Sievers, Dawn M. Albrecht, Ian Grimes, Jennifer M. Weiss, Kristina A. Matkowskyj, Rashmi Agni, Irina Vyazunova, Linda Clipson, Douglas R. Storts, Andrew Thliveris, Richard B. Halberg   +11 more
openalex   +2 more sources