Results 181 to 190 of about 124,795 (370)

Characterizing Microsatellite Instability and Chromosome Instability in Interval Colorectal Cancers

Neoplasia: An International Journal for Oncology Research, 2018
There are a substantial portion of colorectal cancers (CRCs), termed interval CRCs (I-CRCs), that are diagnosed shortly after a negative colonoscopy (i.e., no detectable polyps or CRC) and before recommended follow-up screening.
Amy L. Cisyk, Zoann Nugent, Robert H. Wightman, Harminder Singh, Kirk J. McManus   +4 more
doaj  

Identification of PPFIA3 as a Potential Prognostic and Immune Biomarker Through Pan‐Cancer Analysis

Organ Medicine, EarlyView.
This study reveals a significant increase in the expression of PPFIA3 across various cancers, which is associated with poor prognosis. Notably, in patients receiving anti‐PD‐L1 treatment, high PPFIA3 expression is closely linked to improved survival rates and favorable prognosis, suggesting its potential as a predictive factor for immune checkpoint ...
Xianghong Wang, Rong Lin, Chuanchuan Sun, Niujian Wu, Hongyun Lu   +4 more
wiley   +1 more source

The role of TMEM119 in gastric adenocarcinoma and its specific effects on immunity

Journal of International Medical Research
Objective To investigate the prognostic significance and immunological implication of transmembrane protein 119 (TMEM119) in stomach adenocarcinoma (STAD).
Yating Liu, Xin Yan, Caihao Qu, Futian Tang, Qian Wang, Yumin Li   +5 more
doaj   +1 more source

$M^{2}$Fusion: Bayesian-based Multimodal Multi-level Fusion on Colorectal Cancer Microsatellite Instability Prediction [PDF]

arXiv
Colorectal cancer (CRC) micro-satellite instability (MSI) prediction on histopathology images is a challenging weakly supervised learning task that involves multi-instance learning on gigapixel images. To date, radiology images have proven to have CRC MSI information and efficient patient imaging techniques. Different data modalities integration offers
arxiv  

Clinicopathological and molecular characterization of KRAS wild‐type pancreatic ductal adenocarcinomas reveals precursor lesions with oncogenic mutations and fusions in RAS pathway genes

The Journal of Pathology, EarlyView.
Abstract Pancreatic ductal adenocarcinomas (PDACs) with wild‐type KRAS constitute a small fraction of PDACs, and these tumors were recently shown to harbor frequent actionable oncogenic mutations and fusions. However, the clinicopathological features of KRAS wild‐type PDAC have not been well studied.
Kazuhiro Toriyama, Katsuhiro Masago, Noriko Shibata, Masataka Haneda, Takamichi Kuwahara, Seiji Natsume, Shota Kobayashi, Yasuko Fujita, Eiichi Sasaki, Kenji Yamao, Hiroki Kawashima, Yasuhiro Shimizu, Kazuo Hara, Yasushi Yatabe, Waki Hosoda   +14 more
wiley   +1 more source

Prevalence of minisatellite and microsatellite instability in radiation-induced post-Chernobyl pediatric thyroid carcinomas [PDF]

, 1998
Yuri E. Nikiforov, Marina N. Nikiforova, James A. Fagin   +2 more
openalex   +1 more source

Exome‐wide molecular insights from blood and urine liquid biopsies in genitourinary cancers

UroPrecision, EarlyView.
Abstract Background Liquid biopsy has emerged as a non‐invasive method for real‐time cancer monitoring especially in genitourinary (GU) oncology. Most current studies utilize a panel‐based molecular profiling ranging from 50–600 genes; however, a comprehensive exome‐wide profiling of real‐world patient samples has been lacking. Methods Over 2000 liquid
Eric Jia, Tiantian Zheng, Yong Huang, Pan Du   +3 more
wiley   +1 more source

MICROSATELLITE INSTABILITY IN PROSTATE CANCER

, 1995
Shin Egawa, Kuniaki Sasaki, K Suyama, Yasuhiro Kawakami, M IMAMURA, Τοyoaki Uchida, Ken Koshiba   +6 more
openalex   +2 more sources

Microsatellite instability during the immortalization and transformation of human breast epithelial cells in vitro [PDF]

, 1999
Yajue Huang, Betsy Bove, Yuli Wu, I H Russo, Xiaoqi Yang, Abdel‐Rahman N. Zekri, José Russo   +6 more
openalex   +1 more source

Deciphering the tumor immune microenvironment: Microscale measurements for precision detection and multidimensional analysis

VIEW, EarlyView.
The tumor immune microenvironment (TIME) plays a critical role in cancer progression and treatment response. Advanced tools like nanotechnology‐empowered sensors to precisely detect at microscopic scales are introduced. These innovations improve the ability to predict patient responses to immunotherapies and identify new therapeutic targets, paving the
Lu Wang, Fan Yin, Rongping Luo, Fengqi Dong, Jianxin Lyu, Zhen Wang, Yi Zhang   +6 more
wiley   +1 more source