A multi-task deep learning framework for simultaneous prediction of microsatellite instability and tumor mutational burden in gastric cancer from histopathological images. [PDF]
Chang Y +7 more
europepmc +1 more source
Camrelizumab‐induced reactive cutaneous capillary endothelial proliferation (RCCEP) was frequent yet manageable in patients with advanced esophageal squamous cell carcinoma and correlated with improved response and survival, suggesting RCCEP as a potential on‐treatment biomarker of clinical benefit.
Jia Liu +11 more
wiley +1 more source
Pre-treatment prediction of microsatellite instability in colon cancer: a nomogram model combining clinicopathological features and pre-treatment CT-based radiomics. [PDF]
Wei M, Jia C, Zhang Y, You P, Chen W.
europepmc +1 more source
Comprehensive machine learning analysis of a radiomics-based model for predicting microsatellite instability in right Colon Cancer. [PDF]
Li J +7 more
europepmc +1 more source
Concordance Analysis of Microsatellite Instability via NGS and Mismatch Repair Deficiency via IHC in Endometrial and Colorectal Cancer. [PDF]
Nero C +22 more
europepmc +1 more source
Abstract This study examines the impact of assimilating all‐sky microwave radiances from the Time‐Resolved Observations of Precipitation structure and storm Intensity with a Constellation of Smallsats (TROPICS) mission within the NASA Global Earth Observing System (GEOS) data assimilation and forecasting framework based on the Gridpoint Statistical ...
Min‐Jeong Kim +4 more
wiley +1 more source
Diagnostic Challenges and Clinical Implications of Microsatellite Instability/Mismatch Repair Deficiency in Solid Tumors. [PDF]
Kwak Y, Bae JM, Lee HS.
europepmc +1 more source
YPEL3 functions as a tumor suppressor in HNSCC by inhibiting tumor progression and promoting apoptosis. Mechanistically, it enhances epithelial–immune crosstalk through the CREB1‐mediated CXCL16–CXCR6 axis, facilitating CD8+ T‐cell infiltration and highlighting its potential as a prognostic biomarker and immunotherapy target.
Yalun Li +7 more
wiley +1 more source
<i>Bacteroides fragilis</i> toxin in colorectal tumors activates STAT3 and drives microsatellite instability. [PDF]
Mehmood MS, Danaf N.
europepmc +1 more source
Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer
Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo +6 more
wiley +1 more source

