Results 181 to 190 of about 52,582 (257)

Study on predicting microsatellite instability in rectal cancer using T₂ mapping combined with ADC value. [PDF]

Cancer Imaging
Zhao X, Hou Y, Ma H.
europepmc   +1 more source

Application of Systems Genetics to Investigate Molecular Pathology of Early‐Onset Colorectal Cancer

Chemical Biology &Drug Design, Volume 108, Issue 2, August 2026.
Early‐onset colorectal cancer (EOCRC) presents a complex molecular landscape that requires integrated multi‐omics approaches. This article reviews current applications of systems genetics in EOCRC research and provides a step‐by‐step protocol for network‐based analyses featuring PIK3CA to demonstrate practical application for researchers of all levels.
Minjae J. Kim, Sydney L. Carr, Vishnutheertha Kulkarni, Mary‐Louise Manchadi   +3 more
wiley   +1 more source

Clinical characteristics of endometrial cancers with microsatellite instability-high and <i>BRCA1/2</i> mutations. [PDF]

Front Oncol
Shan Y, Wang Y, Huang L, Li G, Cui Z, Xing X, Yin G.   +6 more
europepmc   +1 more source

Prognostic Value of Systemic Inflammatory Markers in Predicting Peritoneal Metastasis in Gastric and Gastroesophageal Junction Cancer

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT Gastric cancer and gastroesophageal junction cancer, primarily adenocarcinoma, originate in the stomach's mucosa. Peritoneal metastasis is a common pattern in gastric cancer. The neutrophil‐to‐lymphocyte ratio (NLR) and platelet‐to‐lymphocyte ratio (PLR), as systemic inflammation indicators, change before clinical symptoms, aiding early ...
Mahesh Wadhwa, Dipali Raju, Harish Premkumar, Nawaz Usman, Preethi S. Shetty, Naveena A. N. Kumar   +5 more
wiley   +1 more source

A Deep Learning-Based Approach for Explainable Microsatellite Instability Detection in Gastrointestinal Malignancies. [PDF]

J Imaging
Ciardiello L, Agnello P, Petyx M, Martinelli F, Cesarelli M, Santone A, Mercaldo F.   +6 more
europepmc   +1 more source

Systemic Inflammation and Risk of Thromboembolism, Mortality, and Treatment Response in Patients With Cancer Receiving Immune Checkpoint Inhibitors

European Journal of Clinical Investigation, Volume 56, Issue 8, August 2026.
In patients with cancer receiving immune checkpoint inhibitors, systemic inflammatory indices measured at treatment initiation and during the first 3 months were associated with treatment response, survival, and thromboembolism, supporting their potential utility for risk stratification. ABSTRACT Background Immune checkpoint inhibitors (ICI) are widely
Leyla Ay, Ingrid Pabinger, Matthias Preusser, Anna Sophie Berghoff, Christoph Hoeller, Cihan Ay, Florian Moik   +6 more
wiley   +1 more source

Efficacy of Immune Checkpoint Blockade in Advanced Upper Tract Urothelial Cancer With DNA Mismatch Repair Deficiency or Microsatellite Instability. [PDF]

JCO Precis Oncol
Moussa MJ, Andreev-Drakhlin AY, Venkatesan AM, Matin SF, Xiao L, Tidwell RSS, Shah AY, Adriazola AC, Shaw L, Gao J, Lin JK, Goswami S, Msaouel P, Guo CC, Tannir NM, Siefker-Radtke AO, Alhalabi O, Campbell MT.   +17 more
europepmc   +1 more source

Inbreeding and Demographic History of Caribou (Rangifer tarandus) in Western Canada Inferred From Genome‐Wide SNP Data

Evolutionary Applications, Volume 19, Issue 8, August 2026.
ABSTRACT Assessing genetic diversity is essential for conserving endangered populations, yet comprehensive genomic evaluations remain limited for many declining species. Here, we investigated inbreeding levels and effective population sizes (Ne) of caribou (Rangifer tarandus) in western Canada, where populations have experienced pronounced declines ...
Charlotte Bourbon, Samuel Deakin, Anita Michalak, Margaret M. Hughes, Maria Cavedon, Lalenia Neufeld, Agnès Pelletier, Jean Polfus, Helen Schwantje, Caeley Thacker, Marco Musiani, Jocelyn Poissant   +11 more
wiley   +1 more source

Microsatellite instability and its impact on nutritional and inflammatory profiles in colorectal cancer. [PDF]

World J Gastrointest Surg
Qu HD, Gao X, Xiao P, Jiao Y.
europepmc   +1 more source

Adjuvant Atezolizumab for Stage III Deficient Mismatch Repair Colon Cancer—Its Impact on Clinical Practice

MedComm, Volume 7, Issue 8, August 2026.
Yun Wu, Shanshan Weng, Ying Yuan
wiley   +1 more source