Results 161 to 170 of about 89,952 (300)

Low microsatellite instability revisited: a review. [PDF]

Virchows Arch
Grosser B, Kohlruss M, Keller G.
europepmc   +1 more source

Metabolic‐immune interactions in gastric cancer T cells: A single‐cell atlas for prognostic biomarker identification

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract Metabolic alterations and immune dysfunction within the gastric tumor microenvironment critically drive gastric cancer (GC) progression and therapeutic resistance. Although single‐cell RNA sequencing (scRNA‐seq) has unveiled cellular heterogeneity in GC, the metabolic landscapes of tumor cells and their interplay with immune components remain ...
Junjun Liu, Rui Zhao, Guodong Yao, Zhao Liu, Runze Shi, Jingshu Geng, Guanying Liang, Kexin Chen   +7 more
wiley   +1 more source

From Theory to Practice: Which Biomarkers Are Ready for Predicting Response in Advanced HCC?

Liver International, Volume 46, Issue 6, June 2026.
ABSTRACT Systemic therapies for advanced hepatocellular carcinoma (HCC) have expanded considerably with the advent of tyrosine kinase inhibitors, immune checkpoint inhibitors and immunotherapy–anti‐angiogenic combinations. However, despite this therapeutic diversification, first‐line treatment selection remains largely empirical, as few biomarkers are ...
Marie Decraecker, Jean‐Frédéric Blanc, Samuel Amintas, Grégoire Manaud   +3 more
wiley   +1 more source

Exercise serum promotes DNA damage repair and remodels gene expression in colon cancer cells

International Journal of Cancer, Volume 158, Issue 10, Page 2641-2649, 15 May 2026.
What's New? Exercise releases bioactive molecules into the bloodstream that can directly slow cancer cell growth. In colon cancer, this may help limit disease progression. Here, using colon cancer cells, the authors investigated the effects of exercise‐conditioned human serum on DNA repair mechanisms. Notably, acute exercise in humans elicited systemic
Samuel T. Orange, Emily Dodd, Sharanya Nath, Hannah Bowden, Alastair R. Jordan, Hannah Tweddle, Ann Hedley, Ifeoma Chukwuma, Ian Hickson, Sweta Sharma Saha   +9 more
wiley   +1 more source

Mismatch repair deficiency and microsatellite instability in adrenocortical carcinoma. [PDF]

ESMO Open
Altieri B, Kircher S, Herterich S, Jahn A, Teleanu MV, Lippert J, Landwehr LS, Kimpel O, Reuter M, Remde H, Stenzinger A, Glimm H, Bargou RC, Fröhling S, Ronchi CL, Appenzeller S, Fassnacht M, Kroiss M.   +17 more
europepmc   +1 more source

Microsatellite Instability [PDF]

, 2020
openaire   +1 more source

Distribution and prognostic value of T‐cells in primary colorectal cancer and adjacent non‐tumor mucosa in stage IV versus stage I–III patients

International Journal of Cancer, Volume 158, Issue 10, Page 2760-2770, 15 May 2026.
What's New? While colonic mucosa lymphocytes have been quantified in the context of inflammatory diseases, T‐cells in non‐tumor mucosa adjacent to colorectal cancer remain understudied. This study found that in stage IV colorectal cancer (synchronous liver metastasis), higher Foxp3+ T‐cell density and Foxp3+/CD4+ and Foxp3+/CD8+ T‐cell ratios in non ...
Esraa Ali, Wenjing Ye, Sergii Pavlov, Lenka Červenková, Filip Ambrozkiewicz, Ondřej Vyčítal, Petr Hošek, Ondřej Daum, Václav Liška, Kari Hemminki, Andriy Trailin   +10 more
wiley   +1 more source

Therapeutic Targeting of Oxidative Phosphorylation in Microsatellite Instability-High Gastric Cancer. [PDF]

J Cancer
Ang B, Bai Y, Deng X, Wu Q, Wang Y, Xu S, Zhang W, Li Y, Chen D, Li R, Li S, Zhao Z, Zhang Y.   +12 more
europepmc   +1 more source

Adenocarcinoma of the Colon and Microsatellite Instability [PDF]

Mayo Clinic Proceedings, 2018
openaire   +2 more sources

Do all colorectal mucinous adenocarcinomas arise via the serrated neoplasia pathway?

The Journal of Pathology: Clinical Research, Volume 12, Issue 3, May 2026.
Abstract Colorectal mucinous adenocarcinomas (MACs) and serrated adenocarcinomas (SACs) demonstrate considerable overlap in morphological and molecular features, suggesting a spectrum rather than two distinct tumour types. This study investigates the presence of serrated morphological features, precursors, and molecular features in a large cohort of ...
Anne‐Marie Vos, Peter H van Zwam, Natasja Rutgers, Shannon van Vliet, Elisa Vink‐Börger, Rachel S van der Post, Femke Simmer, Iris D Nagtegaal   +7 more
wiley   +1 more source