Results 201 to 210 of about 89,952 (300)

A Deep Learning-Based Approach for Explainable Microsatellite Instability Detection in Gastrointestinal Malignancies. [PDF]

J Imaging
Ciardiello L, Agnello P, Petyx M, Martinelli F, Cesarelli M, Santone A, Mercaldo F.   +6 more
europepmc   +1 more source

Expression of Programmed Death‐Ligand 1 in Cervical Cancer: Correlation With Histologic Subtypes and Clinicopathological Features

Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.
ABSTRACT Background Cervical cancer remains a significant global health challenge, with squamous cell carcinoma (SCC) and adenocarcinoma representing its predominant histologic types. Programmed death‐ligand 1 (PD‐L1) expression in cervical cancer has been implicated in tumor immune evasion, yet its prognostic significance remains unclear.
Zahra Vahedpoor, Amirhasan Matini, Habibollah Rahimi, Majid Lotfinia, Hossein Motedayyen, Leyla Sadat Hejazi   +5 more
wiley   +1 more source

Efficacy and safety of immune checkpoint inhibitors in patients with high microsatellite instability/mismatch repair-deficient advanced cholangiocarcinoma: A propensity score-matched study. [PDF]

JHEP Rep
Piao M, Yang X, Li C, Zhao J, Zhang N, Li J, Huang Z, Li S, Sun B, Yang X, Zhao H.   +10 more
europepmc   +1 more source

Outcomes from the English National Lynch Syndrome transformation project

International Journal of Cancer, Volume 158, Issue 9, Page 2369-2379, 1 May 2026.
What's new? The elevated cancer risk conferred by Lynch syndrome can be mitigated through preventive interventions. However, Lynch syndrome often goes underdiagnosed. The National Lynch Syndrome Transformation Project in England aims to ensure that patients newly diagnosed with colorectal or endometrial cancer are offered testing for the syndrome ...
Kevin J. Monahan, Paul Fleming, Neil A. J. Ryan, Laura Monje‐Garcia, Ruth Armstrong, David N. Church, Jackie Cook, Fiona Lalloo, Sally Lane, Frank D. McDermott, Tracie Miles, Corinne Mallinson, Steven A. Hardy, Simone Gelinas, Francesca Faravelli, Frances Elmslie, Adam C. Shaw   +16 more
wiley   +1 more source

Deficient mismatch repair/microsatellite instability-high colorectal cancer: current treatment paradigms, limitations and future perspectives. [PDF]

BMJ Oncol
Storandt MH, Sinicrope FA.
europepmc   +1 more source

Novel SOX17 frameshift mutations in endometrial cancer are functionally distinct from recurrent missense mutations. [PDF]

, 2017
Cohn, David E, Goodfellow, Paul J, Kurita, Takeshi, Miranda, Mario A, Mutch, David G, O\u27Hern, Matthew J, Sapp, Caroline E, Serna, Vanida A, Walker, Christopher J   +8 more
core   +1 more source

Carbohydrate‐Based Drug Discovery: Synthetic Strategies and Clinical Applications

Israel Journal of Chemistry, Volume 66, Issue 3, May 2026.
The picture depicts the molecules discussed in the review. On the left side, the general scaffold of sugars is shown. Next to it are four carbohydrate‐based molecules, including remdesivir, islatravir, empagliflozin, and Globo‐H. Remdesivir and islatravir contain a substituted ribose ring attached to a modified nucleobase.
Stephan Scheeff, Jemma Arakelyan, Billy Wai‐Lung Ng   +2 more
wiley   +1 more source

Comparing multi-b-value diffusion models and ROI delineation strategies for prediction of p53 abnormality and microsatellite instability in endometrial cancer. [PDF]

BMC Med Imaging
Li Y, Wang X, Xue K, Mao Y, Wang W, Liu X, Wang W, Zhang M.   +7 more
europepmc   +1 more source

Analysis of the Matrix Metalloproteinases Family Profile in Gastric Cancer Suggests Key Matrix Metalloproteinases for Tumor Development and Their Clinical Impact

Molecular Carcinogenesis, Volume 65, Issue 5, Page 577-588, May 2026.
ABSTRACT Gastric cancer (GC) is the fifth most common type worldwide, representing a public health problem. Among the genes related to this tumorigenesis, the family of matrix metalloproteinases (MMPs), essential regulators of the extracellular matrix (ECM), stand out for their involvement in the development and progression of GC.
Aline Costa Bastos, André Salim Khayat, Emanuele Raimunda Louzada Moraes, Ágatha Tereza Miranda Tavares, Ronald Matheus da Silva Mourão, Fabiano Cordeiro Moreira, Samir Mansour Moraes Casseb, Samia Demachki, Geraldo Ishak, Williams Fernandes Barra, Rommel Mario Rodríguez Burbano, Paulo Pimentel de Assumpção   +11 more
wiley   +1 more source

Recurrent microsatellite instability-high thymic carcinoma showing complete response to immune checkpoint inhibitor: A case report. [PDF]

Oncol Lett
Nakagawa T, Aruga N, Watanabe H, Masuda R, Yamada S, Iwazaki M.   +5 more
europepmc   +1 more source