Correction: A two-stage deep learning prediction system for colon cancer microsatellite instability status using CT images. [PDF]
Cui S, Xiong X, Yang X, He J, Shen T.
europepmc +1 more source
Comprehensive Genomic Profiles of Patients With Biliary Tract Cancer
ABSTRACT Purpose Biliary tract cancer (BTC) represents a heterogeneous disease with highly lethal malignancy and poor clinical outcomes. Here, we aimed to evaluate its genomic profiles to promote the development of precision medicine for BTC. Materials and Methods Genomic analysis of 134 BTC patients was performed by using targeted panel sequencing in ...
Xia Yang +4 more
wiley +1 more source
Improving the performance of polymerase chain reaction for microsatellite instability testing in endometrial cancer. [PDF]
Mendiola M +11 more
europepmc +1 more source
Immunotherapy 3.0: Breakthroughs Steering the Next Generation of Cancer Control
ABSTRACT Background Hematologic disorders, including sickle cell disease, anemias, hemoglobinopathies, leukemias, lymphomas, and bleeding disorders, constitute a substantial and growing burden of morbidity and mortality across Africa. Structural health system constraints—limited diagnostic capacity, shortages of trained hematology specialists ...
Emmanuel Ifeanyi Obeagu
wiley +1 more source
Mucinous histology and resistance to immune checkpoint blockade in patients with microsatellite instability-high metastatic colorectal cancer. [PDF]
Nasca V +20 more
europepmc +1 more source
F. nucleatum colonises tumours through mucosal translocation, adjacent‐tissue migration and hematogenous dissemination. It promotes cancer progression via adhesion, inflammation, immune evasion, epigenetic remodelling and metastasis. Its effects on therapy response are tumour‐context dependent. Microbiome‐guided targeting may enable precision oncology.
Feng Zhao +7 more
wiley +1 more source
Correction: Machine learning-based radiomics approach assessing preoperative non-contrast CT for microsatellite instability prediction in colon cancer. [PDF]
Ren D, Wang Y, Chen L, He J, Shen T.
europepmc +1 more source
Methods to estimate marine functional connectivity: A primer
Abstract Organism movement is a key process in the transfer of individuals, genes, functional traits, matter, and energy among habitat patches, at sea and across the land–sea interface. The resulting fluxes, collectively termed marine functional connectivity (MFC), underpin planetary health and an array of ecosystem services.
Anna M. Sturrock +31 more
wiley +1 more source
Analysis of microsatellite instability intensity in single-cell resolution with scMnT reveals tumor heterogeneity in colorectal cancer. [PDF]
Park G, Park J.
europepmc +1 more source
ABSTRACT Background Alterations of the Y chromosome are frequent events in solid tumors, yet their biological and clinical significance remains incompletely understood. In colorectal cancer (CRC), recent studies have suggested context‐dependent roles of Y‐linked genes in tumor progression, while the impact of tumor‐associated loss of the Y chromosome ...
Anaëlle Isnard +7 more
wiley +1 more source

