Results 211 to 220 of about 62,250 (302)

A multi-task deep learning framework for simultaneous prediction of microsatellite instability and tumor mutational burden in gastric cancer from histopathological images. [PDF]

Front Oncol
Chang Y, Chang H, Lv Y, Xi S, Yang J, Wang B, Zheng X, Xie Y.   +7 more
europepmc   +1 more source

Pre-treatment prediction of microsatellite instability in colon cancer: a nomogram model combining clinicopathological features and pre-treatment CT-based radiomics. [PDF]

BMC Med Imaging
Wei M, Jia C, Zhang Y, You P, Chen W.
europepmc   +1 more source

Concordance Analysis of Microsatellite Instability via NGS and Mismatch Repair Deficiency via IHC in Endometrial and Colorectal Cancer. [PDF]

Target Oncol
Nero C, Salvatore L, Duranti S, Anderson G, Mastrantoni L, Karimi M, Mantini G, Minucci A, Maneri G, Giacò L, Santoro A, Panfili A, Piermattei A, Marino I, Caira G, Calegari MA, Trovato G, Iacobelli V, Salutari V, Normanno N, Fanfani F, Scambia G, Tortora G.   +22 more
europepmc   +1 more source

Comprehensive machine learning analysis of a radiomics-based model for predicting microsatellite instability in right Colon Cancer. [PDF]

Front Oncol
Li J, Liu L, Zhong X, Yang R, Wang W, Yin L, Li D, Liu H.   +7 more
europepmc   +1 more source

Closing the Loop in Precision Oncology: A Digital Twin‐Driven Paradigm for Dynamic Decision‐Making

iMetaMed, Volume 2, Issue 2, June 2026.
This review introduces the Closed‐Loop Intelligent Oncology System (CIOS), a five‐layer framework integrating digital twins and AI to enable adaptive, data‐driven cancer treatment. By synthesizing advances in multimodal perception, mechanistic simulation, and safe reinforcement learning, CIOS charts a roadmap toward dynamic, personalized oncology ...
Junye Zhu, Mengqi Yang, Chenxi Ouyang, Lin Zhang   +3 more
wiley   +1 more source

Socio‐ecological models as a framework for 21st‐century genetic counseling

Journal of Genetic Counseling, Volume 35, Issue 3, June 2026.
Abstract Socio‐ecological models and the related concepts of micro‐, meso‐, and macro‐level practice are commonly used in the fields of social work and public health yet have not been thoroughly conceptualized for application to genetic counseling practice, research, and training.
Shana L. Merrill, Rebecca Mueller
wiley   +1 more source

Diagnostic Challenges and Clinical Implications of Microsatellite Instability/Mismatch Repair Deficiency in Solid Tumors. [PDF]

Cancer Res Treat
Kwak Y, Bae JM, Lee HS.
europepmc   +1 more source

Regulation of Immune Checkpoints: From Molecular Mechanisms to Clinical Therapies

MedComm, Volume 7, Issue 6, June 2026.
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by unleashing antitumor immunity. This review comprehensively examines the molecular mechanisms underlying key immune checkpoints—including PD‐1/PD‐L1, CTLA‐4, and TIM‐3—and their clinical applications.
Qintao Ge, Liu Yu, Jiahe Lu, Aihetaimujiang Anwaier, Xiyue Xiao, Yonghao Chen, Dingwei Ye, Hailiang Zhang, Wenhao Xu, Wenbin Dai   +9 more
wiley   +1 more source

<i>Bacteroides fragilis</i> toxin in colorectal tumors activates STAT3 and drives microsatellite instability. [PDF]

Ann Med Surg (Lond)
Mehmood MS, Danaf N.
europepmc   +1 more source