Case Report: Ultrasound features of pathological complete response in middle and low rectal cancer with high microsatellite instability after neoadjuvant immunotherapy: a case series. [PDF]
Liang L +5 more
europepmc +1 more source
Isolation, cloning and characterisation of motifs containing (GA/TC)n rpeeats from vetch, Vicia bithynica [PDF]
Bowater, Richard +2 more
core
Shared risk factors, clinical features, and tumor characteristics across multiple early‐onset cancer types are shown in this Graphical Abstract. Integrative approaches combining molecular pathology, oncology, and population sciences offer opportunities to clarify underlying mechanisms and help us develop preventive strategies for early‐onset cancers ...
Nobuhiro Nakazawa +17 more
wiley +1 more source
Ensemble learning for predicting microsatellite instability in colorectal cancer using pretreatment colonoscopy images and clinical data. [PDF]
You J +6 more
europepmc +1 more source
CD8+ T cell infiltration demonstrates distinct clinical significance across molecular subtypes of gastric cancer. High infiltration correlates with improved survival in EBV‐positive and CIN subtypes, while low infiltration predicts better adjuvant chemotherapy response in MSI patients.
Zhen Ling +9 more
wiley +1 more source
EMQN best practice guidelines for analysis and reporting of microsatellite instability in solid tumours. [PDF]
Gallon R +11 more
europepmc +1 more source
Finding More in Less: Precision Medicine for Pancreatic Cancer Using Residual Cytology Samples
The study evaluates the use of residual liquid‐based cytology (LBC) samples from pancreatic ductal adenocarcinoma (PDAC) for molecular analysis. It shows that LBC samples preserve nucleic acid quality and remain suitable for next‐generation sequencing (NGS) and MSI testing even after prolonged storage, underscoring their value when other samples are ...
Raquel Antón‐Peñalver +17 more
wiley +1 more source
A two-stage deep learning prediction system for colon cancer microsatellite instability status using CT images. [PDF]
Cui S, Xiong X, Yang X, He J, Shen T.
europepmc +1 more source
ABSTRACT Aims Observational studies show metformin use associated with lower cancer risk, although experimental evidence is inconsistent. To provide genetic validation for repositioning of metformin in cancer prevention, we assessed genetically proxied effects of putative metformin targets on cancer outcomes using a drug‐target Mendelian randomization (
Xingyu Shen +7 more
wiley +1 more source
Evaluation of microsatellite instability patterns in mismatch repair deficiency: a retrospective analysis of 285 endometrial cancers. [PDF]
Wang C +5 more
europepmc +1 more source

