Results 231 to 240 of about 62,250 (302)

Efficacy and safety of immune checkpoint inhibitors in patients with high microsatellite instability/mismatch repair-deficient advanced cholangiocarcinoma: A propensity score-matched study. [PDF]

JHEP Rep
Piao M, Yang X, Li C, Zhao J, Zhang N, Li J, Huang Z, Li S, Sun B, Yang X, Zhao H.   +10 more
europepmc   +1 more source

Colorectal Precancerous Lesions: Molecular Mechanisms, Research Tools, and Natural Product‐Based Clinical Translation

MedComm – Oncology, Volume 5, Issue 2, June 2026.
This article systematically elucidates the molecular mechanisms of colorectal precancerous lesions, introduces cutting‐edge research tools like multi‐omics and organoids, and highlights the potential and prospects of natural products such as berberine, resveratrol, and curcumin in preventing and intervening in colorectal carcinogenesis by modulating ...
Shunji Liu, Chujuan Cui, Lingdong Kong, Qiang Xu, Haibo Cheng, Lisha Zhou, Yang Sun   +6 more
wiley   +1 more source

Impact of treatment discontinuation among patients with microsatellite instability or mismatch repair-deficient metastatic colorectal cancer treated with immune checkpoint inhibitors. [PDF]

ESMO Open
Ros J, de Grandis MC, Navarro V, Baraibar I, Salva F, Vaghi C, Garcia A, Alcaraz A, López AM, Rodriguez M, Salvà C, Mulet-Margalef N, Manzano JL, Querol R, Pampols M, Castillo E, Vivancos A, Tabernero J, Elez E.   +18 more
europepmc   +1 more source

Translating Generative Digital Pathology to Clinical Workflows: Insights From Transformer‐Based Pathology Image and Text Alignment Network

iLABMED, Volume 4, Issue 2, Page 123-125, June 2026.
Xin Xin, Guoliang Zheng
wiley   +1 more source

Oncofetal Biology: From Fundamental Mechanisms to Emerging Therapeutic Opportunities

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oncofetal biology provides a transformative framework for understanding cancer initiation, progression, and therapeutic intervention. This review synthesizes the core molecular mechanisms connecting embryonic development and tumorigenesis from a multidisciplinary standpoint and outlines future research trajectories and clinical applications, and we aim
Yang Liu, Kaifeng Niu, Qingran Kong, Shaorong Gao   +3 more
wiley   +1 more source

Recurrent microsatellite instability-high thymic carcinoma showing complete response to immune checkpoint inhibitor: A case report. [PDF]

Oncol Lett
Nakagawa T, Aruga N, Watanabe H, Masuda R, Yamada S, Iwazaki M.   +5 more
europepmc   +1 more source

The Tumor Immune Microenvironment in Endometrial Cancer: Composition, Molecular Subtypes, and Therapeutic Implications

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Endometrial cancer (EC), a major gynecologic malignancy and a representative “cold tumor”, exhibits a tumor immune microenvironment (TIME) influenced by a broad range of cellular and molecular elements, immunosuppressive signals, and pathways of immune evasion.
Jingxuan Ye, Yashi Shi, Alexander Mustea, Xiaodan Mao, Pengming Sun   +4 more
wiley   +1 more source

Deficient mismatch repair/microsatellite instability-high colorectal cancer: current treatment paradigms, limitations and future perspectives. [PDF]

BMJ Oncol
Storandt MH, Sinicrope FA.
europepmc   +1 more source

What practicing pathologists and oncologists should know about the new computational pathology‐based companion diagnostic tools

The Journal of Pathology, Volume 269, Issue 2, Page 143-148, June 2026.
Abstract The integration of artificial intelligence into pathology is transforming the assessment of histological and immunohistochemical (IHC) slides, offering opportunities to reduce variability and streamline diagnostics. In practical terms, most available tools and research models emulate the diagnostic capabilities of pathologists by detecting ...
Diana Montezuma, Sara P. Oliveira, Inti Zlobec, Nadieh Khalili, Jordi Temprana‐Salvador, Sabine Leh, David Ameisen, Mircea‐Sebastian Șerbănescu, Arsela Prelaj, Jakob Nikolas Kather, Norman Zerbe, Vincenzo L'Imperio   +11 more
wiley   +1 more source

Comparing multi-b-value diffusion models and ROI delineation strategies for prediction of p53 abnormality and microsatellite instability in endometrial cancer. [PDF]

BMC Med Imaging
Li Y, Wang X, Xue K, Mao Y, Wang W, Liu X, Wang W, Zhang M.   +7 more
europepmc   +1 more source