Results 261 to 270 of about 88,754 (292)

A Case of Lung Squamous Cell Carcinoma Harboring TP53 Mutation and PLPP5‐FGFR1 Fusion Gene

The Clinical Respiratory Journal, Volume 19, Issue 4, April 2025.
Lung squamous cell carcinoma (LUSC) is a common cancer with poor prognosis. FGFR fusions, including in nonsmall cell lung cancer (NSCLC), are targeted by FGFR inhibitors. This study reports a novel PLPP5‐FGFR1 fusion in a 65‐year‐old LUSC patient, coexisting with a TP53 mutation.
Meng Xiao‐ru, Shi Xiao‐Xiong, Gao Qian, Qu Ya‐jing, Huo Li‐li, Gao Yan‐Yan, Xu Peng‐peng, Ma Guan‐nan, Ren Gui‐bing   +8 more
wiley   +1 more source

Microsatellite Instability, Tumor Mutational Burden, and Response to Immune Checkpoint Blockade in Patients with Prostate Cancer. [PDF]

Clin Cancer Res
Lenis AT, Ravichandran V, Brown S, Alam SM, Katims A, Truong H, Reisz PA, Vasselman S, Nweji B, Autio KA, Morris MJ, Slovin SF, Rathkopf D, Danila D, Woo S, Vargas HA, Laudone VP, Ehdaie B, Reuter V, Arcila M, Berger MF, Viale A, Scher HI, Schultz N, Gopalan A, Donoghue MTA, Ostrovnaya I, Stopsack KH, Solit DB, Abida W.   +29 more
europepmc   +1 more source

Is it time to acknowledge intramucosal colorectal carcinoma?

Histopathology, Volume 86, Issue 5, Page 805-812, April 2025.
Intramucosal colorectal carcinoma should be acknowledged based on the strong association with patients that have a high risk for developing colorectal cancer, in particular patients with Lynch syndrome. Aim The term ‘intramucosal carcinoma’ in the colorectum is controversial when used as a synonym for high‐grade dysplasia.
Elisa Vink‐Börger, Nikki Knijn, Adriaan de Bruine, Jeroen Stavast, Rachel Sophia van der Post, Iris Nagtegaal   +5 more
wiley   +1 more source

A pilot study on the detection of microsatellite instability using long mononucleotide repeats in solid tumors. [PDF]

Oncol Lett
Liu T, Ho CL, Chen YJ, Chen PJ, Chen WL, Lee CT, Chow NH, Huang W, Chen YL.   +8 more
europepmc   +1 more source

Early treatment discontinuation in patients with deficient mismatch repair or microsatellite instability high metastatic colorectal cancer receiving immune checkpoint inhibitors. [PDF]

J Immunother Cancer
Taieb J, Ambrosini M, Alouani E, Lonardi S, Sinicrope FA, Decraecker M, Boileve A, Hafliger E, Mazard T, Pernot S, Parent P, Ros J, Overman MJ, Jayachandran P, Nasca V, Salvatore L, Guimbaud R, Cremolini C, Tougeron D, Pietrantonio F.   +19 more
europepmc   +1 more source

Microsatellite instability is highly prevalent in older patients with colorectal cancer. [PDF]

Front Surg
Jakob D, Orth V, Gödde D, Zirngibl H, Ambe PC.   +4 more
europepmc   +1 more source

ANXA10 sensitizes microsatellite instability-high colorectal cancer to anti-PD-1 immunotherapy via assembly of HLA-DR dimers by regulating CD74. [PDF]

Cell Biol Toxicol
Sun Y, Yang B, Wen T, Guo X, Li D, Shi R, Zhang F, Wang D, Li C, Qu X.   +9 more
europepmc   +1 more source

Immune checkpoint inhibitors for patients with mismatch repair deficient or microsatellite instability-high advanced cancers: a meta-analysis of phase I-III clinical trials. [PDF]

Int J Surg
Wang W, Mei Z, Chen Y, Jiang J, Qu Y, Saifuding K, Zhou N, Bulibu G, Tang Y, Zhai X, Jiang Z.   +10 more
europepmc   +1 more source

Correction: Real-world prevalence of microsatellite instability testing and related status in women with advanced endometrial cancer in Europe. [PDF]

Arch Gynecol Obstet
Kelkar SS, Prabhu VS, Zhang J, Ogando YM, Roney K, Verma RP, Miles N, Marth C.   +7 more
europepmc   +1 more source

Immune microenvironmental heterogeneity according to tumor DNA methylation phenotypes in microsatellite instability-high colorectal cancers. [PDF]

Cancer Immunol Immunother
Kim JH, Hong J, Lee JA, Jung M, Choi E, Cho NY, Kang GH, Kim S.   +7 more
europepmc   +1 more source