Results 261 to 270 of about 868,914 (412)

Microsatellite Instability in the Adenoma-Carcinoma Sequence of the Stomach [PDF]

open access: bronze, 2000
Hee Sung Kim   +4 more
openalex   +1 more source

The impact of Foxp3+ regulatory T‐cells on CD8+ T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley   +1 more source

<i>MLH1</i> Methylation Status and Microsatellite Instability in Patients with Colorectal Cancer. [PDF]

open access: yesGenes (Basel)
Rico-Méndez MA   +10 more
europepmc   +1 more source

Clinical usefulness of microsatellite instability for the prediction of gastric adenoma or adenocarcinoma in patients with chronic gastritis [PDF]

open access: hybrid, 2000
Kazuhiro Kashiwagi   +6 more
openalex   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen   +3 more
wiley   +1 more source

Epacadostat Overcomes Cetuximab Resistance in Colorectal Cancer by Targeting IDO‐Mediated Tryptophan Metabolism

open access: yesCancer Science, EarlyView.
The effect of cetuximab and epacadostat combinative therapy on CRC cells. ABSTRACT Primary or acquired mutations in RAS/RAF genes resulting in cetuximab resistance have limited its clinical application in colorectal cancer (CRC) patients. The mechanism of this resistance remains unclear.
Yimin Zhou   +5 more
wiley   +1 more source

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