Results 271 to 280 of about 124,795 (370)
USP14 inhibits mitophagy and promotes tumorigenesis and chemosensitivity through deubiquitinating BAG4 in microsatellite instability-high colorectal cancer. [PDF]
Wang Z, Yu C, Xie G, Tao K, Yin Z, Lv Q.
europepmc +1 more source
Abstract Objective Recent advancements in genome analyses, including the BRAF gene and mismatch repair (MMR) gene/microsatellite instability (MSI), have revealed the biological diversity of colorectal cancer (CRC). BRAF‐mutated CRC has a poor prognosis; however, cases exhibiting deficient MMR (dMMR)/MSI‐high (MSI‐H) and BRAF gene mutations have ...
Rika Omote+7 more
wiley +1 more source
Transcriptome-Based Survival Analysis Identifies MAP4K4 as a Prognostic Marker in Gastric Cancer with Microsatellite Instability. [PDF]
Huamani Ortiz AJ+8 more
europepmc +1 more source
What's new? Although small intestinal adenocarcinoma (SIA) shares certain similarities with colorectal cancer, its etiology and predisposing conditions presumably are distinct. Due to the rarity of SIA, however, detailed information on predisposing factors is lacking.
Jasmijn D. G. Linssen+8 more
wiley +1 more source
Microsatellite Instability as a Risk Factor for Occult Lymph Node Metastasis in Early-Stage Endometrial Cancer: A Retrospective Multicenter Study. [PDF]
Ronsini C+8 more
europepmc +1 more source
What's new? Aspirin and other nonsteroidal anti‐inflammatory drugs (NSAIDs) may improve survival in certain types of cancer, but evidence has been inconclusive so far regarding their effect on endometrial cancer survival. Here, the authors present data from a large population‐based cohort study in Norway, including 7751 individuals with endometrial ...
Ala Jabri Haug+6 more
wiley +1 more source
Integrative analysis of bulk and single-cell sequencing reveals TNFSF9 as a potential regulator in microsatellite instability stomach adenocarcinoma. [PDF]
Zhou J+9 more
europepmc +1 more source
What's New? The incidence of early‐onset colorectal cancer (EOCRC) has been raising, and stage‐specific characteristics and prognosis need to be clarified. In this study, more than 90% of EOCRC cases presented with symptoms. Among patients with localized cancer, female gender, perineural invasion, and intense treatment were more frequent in early than ...
Erman Akkus+5 more
wiley +1 more source