Results 81 to 90 of about 89,549 (187)

The Importance of DNA Repair in Tumor Suppression

, 2004
The transition from a normal to cancerous cell requires a number of highly specific mutations that affect cell cycle regulation, apoptosis, differentiation, and many other cell functions.
B. Vogelstein, C. J. Sherr, C. Kamp, D. Voet, E. C. Friedberg, Eugene I. Shakhnovich, G. M. Cooper, K. H. Dragnev, Yisroel Brumer   +8 more
core   +1 more source

Microsatellite instability as an expert biomarker in cancer diseases

Journal of Education, Health and Sport
The diagnostic and predictive activities of the oncology service are based on a wide range of immunohistochemical and genetic studies with a different spectrum of applications and different levels of efficacy.
O. Bondar
doaj   +1 more source

Microsatellite instability during the immortalization and transformation of human breast epithelial cells in vitro [PDF]

, 1999
Yajue Huang, Betsy Bove, Yuli Wu, I H Russo, Xiaoqi Yang, Abdel‐Rahman N. Zekri, José Russo   +6 more
openalex   +1 more source

Clinical Aspects of Microsatellite Instability Testing in Colorectal Cancer

Advanced Biomedical Research, 2018
Microsatellite instability (MSI) is a molecular hallmark for some colorectal cancers (CRCs) in which short tandem repeats are prone to mutations along with DNA sequences.
Mehrdad Zeinalian, Morteza Hashemzadeh-Chaleshtori, Rasoul Salehi, Mohammad Hassan Emami   +3 more
doaj   +1 more source

MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas [PDF]

, 1998
Manel Esteller, Ross L. Levine, Stephen B. Baylin, Lora H. Ellenson, James G. Herman   +4 more
openalex   +1 more source

Microsatellite instability—a useful diagnostic tool to select patients at high risk for hereditary non-polyposis colorectal cancer: a study in different groups of patients with colorectal cancer [PDF]

, 1999
C. Lamberti, Roland Kruse, Corina Ruelfs, Reiner Caspari, Y Wang, Matthias Jungck, Micaela Mathiak, Hamid Reza Hosseiny Malayeri, Waltraut Friedl, Tilman Sauerbruch, Peter Propping   +10 more
openalex   +1 more source

Microsatellite Instability and Mutation of DNA Mismatch Repair Genes in Gliomas [PDF]

, 1998
Suet Yi Leung, Tsun Leung Chan, Lap Ping Chung, Annie S Y Chan, Yiu Wah Fan, Kwan Ngai Hung, Wai Kay Kwong, Judy W.C. Ho, Siu Tsan Yuen   +8 more
openalex   +1 more source

Evaluating the Role of Genetic Markers in Predicting Oral Leukoplakia Malignancy Transformation

Journal of Pharmacy and Bioallied Sciences
Background: Oral leukoplakia is a common premalignant lesion in the oral cavity, with varying risks of transformation into oral squamous cell carcinoma (OSCC).
Ahtesham Ahmad Qurishi, Mohamed S. Mohamed Morsy, Abeer M. Atout, Shahad Essa Abzoah, Mohammed Hasan M. Wadani, Nawaf Hussain Ali Ghazwani, Shatha Ahmad Mohammad Jafari   +6 more
doaj   +1 more source

Frequent clonal loss of heterozygosity but scarcity of microsatellite instability at chromosomal breakpoint cluster regions in adult leukemias [PDF]

, 1996
T Pabst, J Schwaller, MJ Bellomo, M Oestreicher, Dominique Mühlematter, André Tichelli, A Tobler, MF Fey   +7 more
openalex   +1 more source

Biomaterial-induced sarcomagenesis is not associated with microsatellite instability [PDF]

, 2018
Sarcomagenesis, in contrast to carcinogenesis, is poorly understood. Microsatellite instability has been implicated in the development of many cancers, in particular those associated with chronic inflammatory conditions.
Hansen, Torsten, Kirkpatrick, C., Schad, Arno, Springer, Erik, Strehl, Annette, Weber, Achim   +5 more
core