Results 241 to 250 of about 57,676 (330)

Comprehensive Whole-Genome Survey and Analysis of the Naozhou Stock of Large Yellow Croakers (<i>Larimichthys crocea)</i>. [PDF]

open access: yesAnimals (Basel)
Wang HJ   +8 more
europepmc   +1 more source

Microsatellite Tandem Repeats Are Abundant in Human Promoters and Are Associated with Regulatory Elements

open access: gold, 2013
Sterling Sawaya   +6 more
openalex   +2 more sources

Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture

open access: yesInternational Journal of Cancer, Volume 158, Issue 2, Page 409-422, 15 January 2026.
Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert   +3 more
wiley   +1 more source

Repetitive DNAs and Karyotype Evolution in Phyllostomid Bats (Chiroptera: Phyllostomidae). [PDF]

open access: yesBiomolecules
Deon GA   +10 more
europepmc   +1 more source

Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 1, Page 108-121, January 2026.
ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco   +18 more
wiley   +1 more source

Instability in the Penta-C and Penta-D Loci in Microsatellite-Unstable Endometrial Cancer. [PDF]

open access: yesInt J Environ Res Public Health
Yilmaz A   +9 more
europepmc   +1 more source

Chronic ER Stress Triggers Cell‐Surface Chaperones as the Therapeutic Targets of CAR Cells in Acute Myeloid Leukemia

open access: yesAdvanced Science, Volume 13, Issue 5, 27 January 2026.
Acute myeloid leukemia (AML) remains a therapeutic challenge due to its heterogeneity and limited targets. Here, multi‐omics analyses are utilized, and it is revealed that AML cells, particularly the FLT3‐ITD+ subtype, undergo chaperone‐mediated ER stress, inducing surface translocation of ER chaperones.
Yimin Zhou   +13 more
wiley   +1 more source

Immunometabolic Rewiring of Dendritic Cells to Overcome Glutamine‐Driven Immune Suppression in Colorectal Cancer

open access: yesAdvanced Science, Volume 13, Issue 5, 27 January 2026.
T26 is an immunometabolic prodrug that modulates colorectal cancer cells. It blocks glutamine metabolism and enhances STING signaling, which promotes the release of reprogrammed extracellular vesicles. These vesicles drive dendritic cell maturation and CD8⁺ T cell activation, thereby strengthening antitumor immunity and improving the effectiveness of ...
Bingjie Zhang   +13 more
wiley   +1 more source

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