Evaluation of microsatellite instability patterns in mismatch repair deficiency: a retrospective analysis of 285 endometrial cancers. [PDF]
Wang C +5 more
europepmc +1 more source
Companion Diagnostics in Clinical Therapy: Current Applications and Future Directions
Companion diagnostics use biomarker‐based assays to stratify patients for precision therapies, improving outcomes while reducing ineffective treatment and side effects. This review summarizes the evolution, regulatory landscape, clinical applications, and technological platforms of CDx, highlighting their role in biomarker‐driven precision therapy.
Yuesong Wu +9 more
wiley +1 more source
The complete chloroplast genome of <i>Calystegia pubescens</i> 'Anestia' Hara 1957 (Convolvulaceae), an endemic species in Asia. [PDF]
Chen H, Zhang JS.
europepmc +1 more source
Early Cancer Detection: What's Going on and What's Next
Multicancer early detection (MCED) platforms have emerged as a promising strategy for the safe and effective early detection of multiple cancer types, with the potential to reduce metastatic burden and improve clinical outcomes, particularly for aggressive malignancies that lack effective population‐level screening.
Emma Di Carlo
wiley +1 more source
Microsatellite development for Theridion evexum (Araneae: Theridiidae) using low-coverage genome sequencing and the MiMi script. [PDF]
Madrigal-Brenes R +3 more
europepmc +1 more source
Clinical Application of Peripheral Blood Biomarkers for Solid Tumors
Peripheral blood biomarkers provide a minimally invasive, dynamic, and potentially more accurate means to obtain a comprehensive tumor profile. Technologies for detecting them are advancing, and with the help of artificial intelligence, they are being used more and more often for cancer diagnosis, prognostic assessment, and therapeutic monitoring ...
Xinru Tu, Mengyan Tu, Junfen Xu
wiley +1 more source
Whole-genome simple sequence repeat development and genetic diversity analysis of sponge gourd (<i>Luffa cylindrica</i>). [PDF]
Cui R +7 more
europepmc +1 more source
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang +7 more
wiley +1 more source
The Application of Microsatellite Markers as Molecular Tools for Studying Genomic Variability in Vertebrate Populations. [PDF]
Kulibaba RO +5 more
europepmc +1 more source
Citrus is a genetically diverse genus widely cultivated across tropical and subtropical regions, yet its varieties often exhibit overlapping morphological traits that complicate accurate identification. In this study, the genetic diversity of nine Citrus varieties was assessed using 36 Simple Sequence Repeats (SSR) markers in combination with key ...
Zunaira Aslam +12 more
wiley +1 more source

