Results 241 to 250 of about 57,676 (330)
Comprehensive Whole-Genome Survey and Analysis of the Naozhou Stock of Large Yellow Croakers (<i>Larimichthys crocea)</i>. [PDF]
Wang HJ +8 more
europepmc +1 more source
A polymorphic microsatellite repeat sequence on chromosome 21 (D21S80)
M J, Owen, A M, Goate, J A, Hardy
openaire +3 more sources
Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture
Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert +3 more
wiley +1 more source
Repetitive DNAs and Karyotype Evolution in Phyllostomid Bats (Chiroptera: Phyllostomidae). [PDF]
Deon GA +10 more
europepmc +1 more source
Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics
ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco +18 more
wiley +1 more source
Instability in the Penta-C and Penta-D Loci in Microsatellite-Unstable Endometrial Cancer. [PDF]
Yilmaz A +9 more
europepmc +1 more source
Acute myeloid leukemia (AML) remains a therapeutic challenge due to its heterogeneity and limited targets. Here, multi‐omics analyses are utilized, and it is revealed that AML cells, particularly the FLT3‐ITD+ subtype, undergo chaperone‐mediated ER stress, inducing surface translocation of ER chaperones.
Yimin Zhou +13 more
wiley +1 more source
Structural heterogeneity and functional convergence of transposable elements. [PDF]
Kosovsky GY, Glazko GV, Glazko TT.
europepmc +1 more source
T26 is an immunometabolic prodrug that modulates colorectal cancer cells. It blocks glutamine metabolism and enhances STING signaling, which promotes the release of reprogrammed extracellular vesicles. These vesicles drive dendritic cell maturation and CD8⁺ T cell activation, thereby strengthening antitumor immunity and improving the effectiveness of ...
Bingjie Zhang +13 more
wiley +1 more source

