Results 241 to 250 of about 28,396 (290)

Companion Diagnostics in Clinical Therapy: Current Applications and Future Directions

open access: yesMedComm, Volume 7, Issue 3, March 2026.
Companion diagnostics use biomarker‐based assays to stratify patients for precision therapies, improving outcomes while reducing ineffective treatment and side effects. This review summarizes the evolution, regulatory landscape, clinical applications, and technological platforms of CDx, highlighting their role in biomarker‐driven precision therapy.
Yuesong Wu   +9 more
wiley   +1 more source

Early Cancer Detection: What's Going on and What's Next

open access: yesMedComm, Volume 7, Issue 3, March 2026.
Multicancer early detection (MCED) platforms have emerged as a promising strategy for the safe and effective early detection of multiple cancer types, with the potential to reduce metastatic burden and improve clinical outcomes, particularly for aggressive malignancies that lack effective population‐level screening.
Emma Di Carlo
wiley   +1 more source

Clinical Application of Peripheral Blood Biomarkers for Solid Tumors

open access: yesMedComm, Volume 7, Issue 3, March 2026.
Peripheral blood biomarkers provide a minimally invasive, dynamic, and potentially more accurate means to obtain a comprehensive tumor profile. Technologies for detecting them are advancing, and with the help of artificial intelligence, they are being used more and more often for cancer diagnosis, prognostic assessment, and therapeutic monitoring ...
Xinru Tu, Mengyan Tu, Junfen Xu
wiley   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang   +7 more
wiley   +1 more source

The Application of Microsatellite Markers as Molecular Tools for Studying Genomic Variability in Vertebrate Populations. [PDF]

open access: yesCurr Issues Mol Biol
Kulibaba RO   +5 more
europepmc   +1 more source

Genetic Diversity Assessment of Citrus Varieties Using Morphological, Biochemical, and Simple Sequence Repeats Marker Approaches

open access: yesNew Zealand Journal of Crop and Horticultural Science, Volume 54, Issue 1, March 2026.
Citrus is a genetically diverse genus widely cultivated across tropical and subtropical regions, yet its varieties often exhibit overlapping morphological traits that complicate accurate identification. In this study, the genetic diversity of nine Citrus varieties was assessed using 36 Simple Sequence Repeats (SSR) markers in combination with key ...
Zunaira Aslam   +12 more
wiley   +1 more source

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