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A comparison of procedures for analysing microsatellite (CA)-repeat polymorphisms

Molecular and Cellular Probes, 1992
Dinucleotide repeat sequences ('microsatellites') have been used as polymorphic genetic markers following amplification in the polymerase chain reaction (PCR). We have compared several methods of analysing the PCR products. The most reliable and unambiguous results were obtained when the PCR products were probed with a specific dinucleotide repeat ...
Margaret R Wallace
exaly   +3 more sources

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Trinucleotide repeats and other microsatellites in yeasts

Research in Microbiology, 1999
Microsatellites are direct tandem DNA repeats found in all genomes. A particular class of microsatellites, called trinucleotide repeats, is responsible for a number of neurological disorders in humans. We review here our current state of knowledge on trinucleotide repeat instability, and discuss the molecular mechanisms that may be involved in ...
G F, Richard, C, Hennequin, A, Thierry, B, Dujon   +3 more
openaire   +2 more sources

Microsatellite Repeats in Mitochondrial Genomes

Proceedings of the 2015 International Conference on Advanced Research in Computer Science Engineering & Technology (ICARCSET 2015), 2015
Mitochondria also known as the powerhouses of the cells have their own DNA sequence and exhibit sequence similarity with bacterial genomes. Microsatellites are a special class of DNA repeats that are found to be helpful to understand evolution, diseases, and phylogeny are widely used in various applications including DNA Fingerprinting, Forensics ...
G. V. Padma Raju, P. Srinivasa Rao, Ch. Someswara Rao, V. Chandra Sekhar, Suresh B. Mudunuri   +4 more
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Analysis of microsatellite repeats in pediatric brain tumors

Cancer Genetics and Cytogenetics, 1995
Tumorigenesis has been shown to proceed through a series of genetic alterations involving protooncogenes and tumor suppressor genes. However, investigation of genomic instability of microsatellites has disclosed a new mechanism for human carcinogenesis, which is involved not only in hereditary nonpolyposis colon cancer (HNPCC) but also in a number of ...
N, Amariglio, E, Friedman, O, Mor, H, Stiebel, C, Phelan, P, Collins, M, Nordenskjold, F, Brok-Simoni, G, Rechavi   +8 more
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Microsatellite Repeats: Canaries in the Coalmine

2013
Our genomes are much more dynamic than we ever imagined, creating variation that is good for evolution, but often bad for the individual. Microsatellite repeats constitute especially plastic genomic elements that can operate as rheostats to fine-tune gene function.
Nimrat Chatterjee, Beatriz A. Santillan, John H. Wilson   +2 more
openaire   +1 more source

Grapevine fingerprinting using microsatellite repeats

1994
Five different microsatellite loci have been amplified through PCR (Polymerase Chain Reaction) in order to find polymorphisms useful for identification of 16 cvs and 42 clones or populations of Vitis vinifera L. No genetic variability was detected among clones and populations.
CIPRIANI, Guido, FRAZZA G., PETERLUNGER, Enrico, TESTOLIN, Raffaele   +3 more
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Molecular characterization of GATA/GACA microsatellite repeats in tomato

Genome, 1997
Microsatellite repeats like GATA or GACA display a degree of variability that allows their use in cultivar identification. Southern hybridization with oligonucleotide probes complementary to these microsatellites were used for the detection of polymorphisms.
Vosman, B., Arens, P.F.P.
openaire   +3 more sources

Instability of short tandem repeats (microsatellites) in human cancers

Nature Genetics, 1994
The allele sizes of polymorphic microsatellite repeats in DNA from human cancers were compared to normal DNA from the same patients. In 16 out of 196 paired samples (8%), we found evidence of an extra allele of a different size in the tumour which was not present in the normal DNA.
Wooster, R., Cleton-Jansen, A. M., Collins, N., Mangion, J., Cornelis, R. S., Cooper, C. S., Gusterson, B. A., Ponder, B. A.J., von Deimling, A., Wiestler, O. D., Cornelisse, C. J., Devilee, P., Stratton, M. R.   +12 more
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Microsatellite repeat polymorphism at the D13S197 locus

Human Molecular Genetics, 1993
H K, Hong, R, Giorda, L M, Yu, M, Trucco, A, Chakravarti   +4 more
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An equine tetranucleotide repeat: microsatellite MPZ001

Animal Genetics, 1994
Breen M., Downs P., Irvin Z., Bell K.
openaire   +5 more sources