Extended microsatellite analysis in microsatellite stable, MSH2 and MLH1 mutation-negative HNPCC patients: Genetic reclassification and correlation with clinical features [PDF]
, 2004 Background: Hereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal dominant disorder predisposing to predominantly colorectal cancer (CRC) and endometrial cancer frequently due to germline mutations in DNA mismatch repair (MMR) genes, mainly ...
Baretton, G. +9 more
core +1 more source
APMicroDB: A microsatellite database of Acyrthosiphon pisum
Genomics Data, 2017 Pea aphids represent a complex genetic system that could be used for QTL analysis, genetic diversity and population genetics studies. Here, we described the development of first microsatellite repeat database of the pea aphid (APMicroDB), accessible at ...
Ritika Bishnoi, Deepak Singla
doaj +1 more source
FishesWe conducted a comparative analysis of the identified microsatellite sequences across the genomes of nine sillaginids. We examined the microsatellites with motifs ranging from 1 to 6 bp in length and analyzed their distribution and frequency across ...
Yinquan Qu +4 more
doaj +1 more source
Analysis of microsatellite polymorphism in inbred knockout mice. [PDF]
PLoS ONE, 2012 Previously, we found that the genotype of 42 out of 198 mouse microsatellite loci, which are distributed among all chromosomes except the Y chromosome, changed from monomorphism to polymorphism (CMP) in a genetically modified inbred mouse strain. In this
Baofen Zuo +8 more
doaj +1 more source
Advanced Science, EarlyView.This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang +15 more
wiley +1 more source
Cytogenetic characterisation and chromosomal mapping of microsatellite and telomeric repeats in two gecko species (Reptilia, Gekkonidae) from Thailand [PDF]
, 2021 Weera Thongnetr +5 more
openalex +2 more sources
AT-rich microsatellite loci development for Fejervarya multistriata by Illumina HiSeq sequencing
Acta Herpetologica, 2019 In our study, a total of 2561 sequences that contained microsatellite loci were found potentially to be used for primer design. Furthermore, Illumina HiSeq sequencing technology identified trinucleotide repeats and AT-rich repeats with the the highest ...
Yan-Mei Wang +3 more
doaj +1 more source
Comparative in silico analysis of SSRs in coding regions of high confidence predicted genes in Norway spruce (Picea abies) and Loblolly pine (Pinus taeda) [PDF]
, 2015 Background: Microsatellites or simple sequence repeats (SSRs) are DNA sequences consisting of 1-6 bp tandem repeat motifs present in the genome. SSRs are considered to be one of the most powerful tools in genetic studies.
García-Gil, Maria Rosario +3 more
core +2 more sources
Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome
Advanced Science, EarlyView.This study introduces a new hypothesis: exons, introns, and intergenic segments are non‐random projections of the functional layers of 3D structure of chromatin packing domains. Evidence is presented that this “geometric code” may encode volumetric structure, reconciling epigenetic patterns, correlates with oncogenic mutations, acting as a potential ...
Luay M. Almassalha +11 more
wiley +1 more source
Characterization of Duck Microsatellite Repeat Sequences
Japan Agricultural Research Quarterly: JARQ, 2001 We cloned duck microsatellite repeat sequences from genomic DNA of an Indonesian native duck to evaluate the genetic relationships among native breeds of duck. A (CA) n - enriched library was constructed using the method of Takahashi et al. (1996) with modifications. In the library, 8.3% of the clones were CA-positive.
Hideaki TAKAHASHI +4 more
openaire +2 more sources