Results 71 to 80 of about 68,764 (347)
Molecular cytogenetic differentiation of paralogs of Hox paralogs in duplicated and re-diploidized genome of the North American paddlefish (Polyodon spathula). [PDF]
, 2017 BackgroundAcipenseriformes is a basal lineage of ray-finned fishes and comprise 27 extant species of sturgeons and paddlefishes. They are characterized by several specific genomic features as broad ploidy variation, high chromosome numbers, presence of ...
Amemiya, Chris T +7 more
core +4 more sources
Alu Repeats: A Source for the Genesis of Primate Microsatellites
Genomics, 1995 As a result of their abundance, relatively uniform distribution, and high degree of polymorphism, microsatellites and minisatellites have become valuable tools in genetic mapping, forensic identity testing, and population studies. In recent years, a number of microsatellite repeats have been found to be associated with Alu interspersed repeated DNA ...
James L. Weber +4 more
openaire +2 more sources
Microsatellite Expansion Diseases: Repeat Toxicity Found in Translation [PDF]
Neuron, 2017 Sellier et al. (2017) show that translation of expanded CGG repeats in fragile X-associated tremor/ataxia syndrome is initiated at an upstream ACG near-cognate start codon. The resulting polyglycine-containing protein, but not repeat RNA, is pathogenic by disrupting the nuclear lamina.
Joel D. Richter, Fen-Biao Gao
openaire +3 more sources
AT-rich microsatellite loci development for Fejervarya multistriata by Illumina HiSeq sequencing
Acta Herpetologica, 2019 In our study, a total of 2561 sequences that contained microsatellite loci were found potentially to be used for primer design. Furthermore, Illumina HiSeq sequencing technology identified trinucleotide repeats and AT-rich repeats with the the highest ...
Yan-Mei Wang +3 more
doaj +1 more source
Analysis of microsatellite polymorphism in inbred knockout mice. [PDF]
PLoS ONE, 2012 Previously, we found that the genotype of 42 out of 198 mouse microsatellite loci, which are distributed among all chromosomes except the Y chromosome, changed from monomorphism to polymorphism (CMP) in a genetically modified inbred mouse strain. In this
Baofen Zuo +8 more
doaj +1 more source
MAg: a simple learning-based patient-level aggregation method for detecting microsatellite instability from whole-slide images [PDF]
arXiv, 2022 The prediction of microsatellite instability (MSI) and microsatellite stability (MSS) is essential in predicting both the treatment response and prognosis of gastrointestinal cancer. In clinical practice, a universal MSI testing is recommended, but the accessibility of such a test is limited.
arxiv
Patient-level Microsatellite Stability Assessment from Whole Slide Images By Combining Momentum Contrast Learning and Group Patch Embeddings [PDF]
arXiv, 2022 Assessing microsatellite stability status of a patient's colorectal cancer is crucial in personalizing treatment regime. Recently, convolutional-neural-networks (CNN) combined with transfer-learning approaches were proposed to circumvent traditional laboratory testing for determining microsatellite status from hematoxylin and eosin stained biopsy whole
arxiv
Population Ecology, EarlyView.In this study, we compared three methods for kinship identification using different algorithms in samples of wild Pacific bluefin tuna and generated genotyping data. The three methods resulted in different numbers of inferred kinship pairs for both generated and actual data. Particularly for the half‐sibling pairs, considerable number of false‐positive
Yohei Tsukahara +5 more
wiley +1 more source
CPT: Pharmacometrics &Systems Pharmacology, Volume 12, Issue 1, Page 87-94, January 2023., 2023 Abstract Dostarlimab (JEMPERLI) is an anti‐programmed cell death protein‐1 (PD‐1) monoclonal antibody (mAb) which is approved by the US Food and Drug Administration for patients with recurrent/advanced mismatch repair‐deficient solid tumors, including endometrial cancer, following progression on prior treatment, with approval based on data from the ...
Daren Austin +4 more
wiley +1 more source
Learning Constrained Corner Node Trajectories of a Tether Net System for Space Debris Capture [PDF]
arXiv, 2023 The earth's orbit is becoming increasingly crowded with debris that poses significant safety risks to the operation of existing and new spacecraft and satellites. The active tether-net system, which consists of a flexible net with maneuverable corner nodes launched from a small autonomous spacecraft, is a promising solution for capturing and disposing ...
arxiv