Results 91 to 100 of about 28,249 (264)

α2,3‐Sialyltransferase (ST3Gal1) regulates endometrioid‐type epithelial ovarian cancer cell migration and invasion via VEGF‐R2/JAK2/STAT3 signaling cascades

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To investigate the role of ST3 β‐galactoside α‐2,3‐sialyltransferase 1 (ST3Gal1) and vascular endothelial growth factor receptor 2 (VEGF‐R2) in endometrioid‐type epithelial ovarian cancer (E‐OC) because aberrant α2,3‐sialylation mediated by ST3Gal1 and VEGF‐R2‐related angiogenesis is linked with tumor progression. Methods ST3Gal1 and
Wei‐Ting Chao   +5 more
wiley   +1 more source

Genome-wide identification of microsatellites in white clover (Trifolium repens L.) using FIASCO and phpSSRMiner

open access: yesPlant Methods, 2008
Background Allotetraploid white clover (Trifolium repens L.) is an important forage legume widely cultivated in most temperate regions. Only a small number of microsatellite markers are publicly available and can be utilized in white clover breeding ...
Bouton Joseph H   +4 more
doaj   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik   +3 more
wiley   +1 more source

SATIN: a micro and mini satellite mining tool of total genome and coding regions with analysis of perfect repeats polymorphism in coding regions

open access: yesBMC Bioinformatics
Background Tandem repeats are specific sequences in genomic DNA repeated in tandem that are present in all organisms. Among the subcategories of TRs we have Satellite repeats, that is divided into macrosatellites, minisatellites, and microsatellites ...
Carlos Willian Dias Dantas   +5 more
doaj   +1 more source

Artificial Intelligence for Identifying Tumor‐Reactive CD8+ T Cells: Biological Principles, Computational Advances, and Future Directions

open access: yesMed Research, EarlyView.
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang   +4 more
wiley   +1 more source

An insight of genetic polymorphism and the commonly studied polymorphisms associated with oral cancer

open access: yesSRM Journal of Research in Dental Sciences, 2014
Oral and pharyngeal cancers are some of the most common cancers worldwide. The risk of developing oral cancer is modified by environment, lifestyle, genetics, and a combination of these factors.
Jeevankumar Sangeetha   +4 more
doaj   +1 more source

Seagrass species diversity in Tanzania based on morphological and molecular data

open access: yesNordic Journal of Botany, EarlyView.
Seagrass diversity along the Tanzanian coast has been documented mainly through morphology, with limited molecular reference data available for Tanzania and the wider Western Indian Ocean. This study combined morphological identification with nuclear ribosomal internal transcribed spacer (ITS) and plastid ribulose‐1,5‐bisphosphate carboxylase/oxygenase
James Leonard Lusana   +1 more
wiley   +1 more source

Leaf micromorphology and genetic diversity analysis of Iranian Hordeum species using ISSR and SCoT markers

open access: yesNordic Journal of Botany, EarlyView.
The genus Hordeum (Poaceae), of the tribe Triticeae, comprises approximately 32 species with substantial potential for barley improvement. Hordeum vulgare is an economically important cereal widely cultivated across diverse environments, from the Arctic to desert and humid regions.
Maryam Keshavarzi   +2 more
wiley   +1 more source

Comparative chromosomal mapping of microsatellite repeats reveals divergent patterns of accumulation in 12 Siluridae (Teleostei: Siluriformes) species. [PDF]

open access: yesGenet Mol Biol, 2020
Ditcharoen S   +9 more
europepmc   +1 more source

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