Results 91 to 100 of about 197,824 (292)

Characterization of new Schistosoma mansoni microsatellite loci in sequences obtained from public DNA databases and microsatellite enriched genomic libraries

Memorias do Instituto Oswaldo Cruz, 2002
In the last decade microsatellites have become one of the most useful genetic markers used in a large number of organisms due to their abundance and high level of polymorphism. Microsatellites have been used for individual identification, paternity tests,
NB Rodrigues, PT LoVerde, AJ Romanha, G Oliveira   +3 more
doaj   +1 more source

Rapid microsatellite isolation from a butterfly by de novo transcriptome sequencing: performance and a comparison with AFLP-derived distances. [PDF]

PLoS ONE, 2010
BACKGROUND: The isolation of microsatellite markers remains laborious and expensive. For some taxa, such as Lepidoptera, development of microsatellite markers has been particularly difficult, as many markers appear to be located in repetitive DNA and ...
Alexander S Mikheyev, Tanya Vo, Brian Wee, Michael C Singer, Camille Parmesan   +4 more
doaj   +1 more source

Quasimonomorphic Mononucleotide Repeats for High‐Level Microsatellite Instability Analysis [PDF]

Disease Markers, 2004
Microsatellite instability (MSI) analysis is becoming more and more important to detect sporadic primary tumors of the MSI phenotype as well as in helping to determine Hereditary Non‐Polyposis Colorectal Cancer (HNPCC) cases. After some years of conflicting data due to the absence of consensus markers for the MSI phenotype, a meeting held in Bethesda ...
Asad Umar, Olivier Buhard, Nirosha Suraweera, Aude Lectard, Alex Duval, Richard Hamelin   +5 more
openaire   +2 more sources

Development and Evaluation of Microsatellite Markers for a Native Prairie Perennial, Echinacea angustifolia (Asteraceae)

Applications in Plant Sciences, 2013
Premise of the study: Microsatellite loci for the native prairie perennial Echinacea angustifolia were developed and evaluated for future use in population structure and paternity studies.
Jennifer L. Ison, Stuart Wagenius, Diedre Reitz, Mary V. Ashley   +3 more
doaj   +1 more source

Fusobacterium nucleatum infection correlates with two types of microsatellite alterations in colorectal cancer and triggers DNA damage

Gut Pathogens, 2020
Fusobacterium nucleatum (Fn) is frequently found in colorectal cancers (CRCs). High loads of Fn DNA are detected in CRC tissues with microsatellite instability-high (MSI-H), or with the CpG island hypermethylation phenotype (CIMP).
Yoshiki Okita, Minoru Koi, Koki Takeda, Ryan Ross, Bhramar Mukherjee, Erika Koeppe, Elena M. Stoffel, Joseph A. Galanko, Amber N. McCoy, Temitope O. Keku, Yoshinaga Okugawa, Takahito Kitajima, Yuji Toiyama, Eric Martens, John M. Carethers   +14 more
doaj   +1 more source

Development and characterization of microsatellite loci for Khaya senegalensis (Meliaceae)

, 2010
Premise of the study: Microsatellite loci were developed to characterize genetic variation and population subdivision in Khaya senegalensis (Desr.) A. Juss.
Prentis, Peter, M. J. Dieters, P. J. Prentis, Dieters, Mark, Godwin, Ian, G. J. Sexton, Frere, C H, Sexton, Gary, Sexton, G J, Godwin, I D, I. D. Godwin, Frere, Celine, Dieters, M J, C. H. Frere, Prentis, P J   +14 more
core   +1 more source

Model‐based clinical pharmacology profiling of subcutaneous nivolumab in renal cell carcinoma: Bridging to alternative dosing regimens and indications

Clinical Pharmacology &Therapeutics, EarlyView.
A novel model‐informed drug development (MIDD) approach was employed to derive the coprimary endpoints (time‐averaged serum concentration over 28 days [Cavgd28] and minimum serum concentration at steady state [Cminss]) of the phase III CheckMate 67T study (NCT04810078).
Yue Zhao, Zheyi Hu, Elizabeth Gibson, Li Zhu, Heather Vezina, Anna G. Kondic   +5 more
wiley   +1 more source

Genome-wide mapping and characterization of microsatellites in the swamp eel genome

Scientific Reports, 2017
We described genome-wide screening and characterization of microsatellites in the swamp eel genome. A total of 99,293 microsatellite loci were identified in the genome with an overall density of 179 microsatellites per megabase of genomic sequences.
Zhigang Li, Feng Chen, Chunhua Huang, Weixin Zheng, Chunlai Yu, Hanhua Cheng, Rongjia Zhou   +6 more
doaj   +1 more source

Improving genetic diagnosis of hereditary tumor syndromes: From expanded gene panels to functional genomics

International Journal of Cancer, EarlyView.
Abstract Genetic tumor risk syndromes (genturis) contribute substantially to the overall cancer burden and provide opportunities for early detection, prevention, and individualized treatment. Yet, many affected individuals remain undiagnosed due to restrictive testing criteria and challenges in variant interpretation.
Mayra Sauer, Morghan C. Lucas, Vitus Prokosch, Thomas Keßler, Thomas Risch, Andreas Laner, Jan Henkel, Anna Benet‐Pagès, Ariane Hallermayr, Verena Steinke‐Lange, Elke Holinski‐Feder, Barbara Klink   +11 more
wiley   +1 more source

Development and Characterization of 10 Microsatellite Markers in Sagina nodosa (Caryophyllaceae)

Applications in Plant Sciences, 2014
Premise of the study: We developed 10 novel microsatellite loci for Sagina nodosa, a diploid perennial arctic-alpine herb. To our knowledge, these are the first microsatellite loci for a Sagina species.
Tarjinder Singh, Joan Edwards, Luana S. Maroja   +2 more
doaj   +1 more source