Results 101 to 110 of about 197,824 (292)

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia   +4 more
wiley   +1 more source

Isolation and Characterization of 27 Microsatellite Markers for the Endemic Species Diplarche multiflora (Ericaceae)

open access: yesApplications in Plant Sciences, 2013
Premise of the study: Microsatellite markers from the genome of Diplarche multiflora were developed and characterized to investigate its genetic diversity and population structure.
Lin Zhang, Zhi-Rong Zhang, Lian-Ming Gao
doaj   +1 more source

Comparison between two approaches to modeling microsatellite DNA repeats: infinite dimensional model and its n-dimensional [PDF]

open access: yes, 2011
Two approaches to modeling microsatellite DNA repeats are considered. The former is an infinite dimensional system based on the theory of branching random walks which dynamic properties are characterized using Laplace transforms and Laplace asymptotic ...
Białka, M.
core  

Colorectal Cancer Screening in Hereditary and Familial High‐Risk Populations: Best Practices and Future Directions

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer‐related morbidity and mortality worldwide yet is largely preventable through effective screening and surveillance. While most CRC cases are sporadic, a substantial proportion occur in individuals at increased risk due to hereditary cancer syndromes or family history who require tailored
Ophir Gilad   +5 more
wiley   +1 more source

Characterization of Waxy microsatellite classes that are closely linked to the rice Waxy gene and amylose content in Thai rice germplasm [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2003
Sixty-eight strains belonging to two species of Oryza were characterized by using Wx microsatellite, (CT)n repeats that are closely linked to the rice Waxy gene.
Preecha Prathepha
doaj  

Fosmid library end sequencing reveals a rarely known genome structure of marine shrimp Penaeus monodon

open access: yesBMC Genomics, 2011
Background The black tiger shrimp (Penaeus monodon) is one of the most important aquaculture species in the world, representing the crustacean lineage which possesses the greatest species diversity among marine invertebrates. Yet, we barely know anything
Chen Ming   +14 more
doaj   +1 more source

Characterization of microsatellite markers in peach [Prunus persica (L.) Batsch]

open access: yes, 2000
Microsatellites have emerged as an important system of molecular markers. We evaluated the potential of microsatellites for use in genetic studies of peach [Prunus persica (L.) Batsch].
Baird, W V   +9 more
core   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

Tandem repeat copy-number variation in protein-coding regions of human genes [PDF]

open access: yes, 2005
BACKGROUND: Tandem repeat variation in protein-coding regions will alter protein length and may introduce frameshifts. Tandem repeat variants are associated with variation in pathogenicity in bacteria and with human disease.
O'Dushlaine, Colm T.   +7 more
core   +1 more source

Liquid biopsy across cancers: Integrating circulating biomarkers, tumor biology, artificial intelligence, and clinical translation

open access: yesInterdisciplinary Medicine, EarlyView.
Liquid biopsy uses non‐invasive sampling of blood or body fluids to isolate circulating analytes, including circulating tumor DNA, circulating tumor cells, extracellular vesicles, and RNA. These are analyzed using next‐generation sequencing, qPCR, and proteomics to inform cancer detection, monitoring, and characterization. Figure created with BioRender.
Jaswinder Singh   +2 more
wiley   +1 more source

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