Results 111 to 120 of about 197,824 (292)

Biodiversity of 52 chicken populations assessed by microsatellite typing of DNA pools [PDF]

open access: yes, 2003
In a project on the biodiversity of chickens funded by the European Commission (EC), eight laboratories collaborated to assess the genetic variation within and between 52 populations from a wide range of chicken types.
Kari Elo   +92 more
core   +1 more source

Focusing on the relevant probabilities in population assignment to identify and correct bias

open access: yesThe Journal of Wildlife Management, EarlyView.
Understanding and calculating conditional probabilities is essential to avoid misinterpretation of population assignment results. We demonstrate how to calculate conditional probabilities for assignments, identify the conditions under which the ability to assign individuals accurately is poor, and provide suggestions on how to mitigate these issues ...
Alyssa Green   +3 more
wiley   +1 more source

Isolation and Characterization of 20 Polymorphic Microsatellite Markers for Juglans mandshurica (Juglandaceae)

open access: yesApplications in Plant Sciences, 2013
Premise of the study: Fifty microsatellite loci were developed for the endangered species Juglans mandshurica to investigate its genetic diversity and population structure.
Chang-Mei Chen   +4 more
doaj   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik   +3 more
wiley   +1 more source

Microsatellite Primers in the Lichen Symbiotic Alga Trebouxia decolorans (Trebouxiophyceae)

open access: yesApplications in Plant Sciences, 2013
Premise of the study: Polymorphic microsatellite markers were developed for the symbiotic green alga Trebouxia decolorans to study fine-scale population structure and clonal diversity.
Francesco Dal Grande   +3 more
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Artificial Intelligence for Identifying Tumor‐Reactive CD8+ T Cells: Biological Principles, Computational Advances, and Future Directions

open access: yesMed Research, EarlyView.
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang   +4 more
wiley   +1 more source

Application of a double-enrichment procedure for microsatellite isolation and the use of tailed primers for high throughput genotyping

open access: yesGenetics and Molecular Biology, 2007
The number of microsatellite loci and their allelic diversity contribute to increase accuracy and informativity of genetic estimates, however, the isolation of microsatellite loci is not only laborious but also quite expensive.
Fábio Mendonça Diniz   +4 more
doaj   +1 more source

Validation of Saccharomyces cerevisiae Strains for Novel CRISPR-Based Proteomics Analysis of CCTG Microsatellite Repeats [PDF]

open access: yes, 2020
Genetic instability in regions with simple DNA sequence repeats, or microsatellites, contribute to a number of human diseases. The CCTG repeat in the ZNF9 gene (zinc finger protein 9) is one such microsatellite sequence, where excessive repeats (>50 ...
Meghan O'Donnell
core  

AI‐Driven Rational Design of Nanotherapeutics for Pancreatic Ductal Adenocarcinoma

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a formidable malignancy characterized by late diagnosis, high recurrence rates, and pronounced chemoresistance. While nanoparticle‐based drug delivery systems (NDDS) offer theoretical advantages over conventional therapies, their clinical translation in PDAC has been severely limited.
Seohyun Choo   +4 more
wiley   +1 more source

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