Results 111 to 120 of about 197,824 (292)
Biodiversity of 52 chicken populations assessed by microsatellite typing of DNA pools [PDF]
In a project on the biodiversity of chickens funded by the European Commission (EC), eight laboratories collaborated to assess the genetic variation within and between 52 populations from a wide range of chicken types.
Kari Elo +92 more
core +1 more source
Focusing on the relevant probabilities in population assignment to identify and correct bias
Understanding and calculating conditional probabilities is essential to avoid misinterpretation of population assignment results. We demonstrate how to calculate conditional probabilities for assignments, identify the conditions under which the ability to assign individuals accurately is poor, and provide suggestions on how to mitigate these issues ...
Alyssa Green +3 more
wiley +1 more source
Premise of the study: Fifty microsatellite loci were developed for the endangered species Juglans mandshurica to investigate its genetic diversity and population structure.
Chang-Mei Chen +4 more
doaj +1 more source
Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik +3 more
wiley +1 more source
Microsatellite Primers in the Lichen Symbiotic Alga Trebouxia decolorans (Trebouxiophyceae)
Premise of the study: Polymorphic microsatellite markers were developed for the symbiotic green alga Trebouxia decolorans to study fine-scale population structure and clonal diversity.
Francesco Dal Grande +3 more
doaj +1 more source
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang +4 more
wiley +1 more source
The number of microsatellite loci and their allelic diversity contribute to increase accuracy and informativity of genetic estimates, however, the isolation of microsatellite loci is not only laborious but also quite expensive.
Fábio Mendonça Diniz +4 more
doaj +1 more source
Validation of Saccharomyces cerevisiae Strains for Novel CRISPR-Based Proteomics Analysis of CCTG Microsatellite Repeats [PDF]
Genetic instability in regions with simple DNA sequence repeats, or microsatellites, contribute to a number of human diseases. The CCTG repeat in the ZNF9 gene (zinc finger protein 9) is one such microsatellite sequence, where excessive repeats (>50 ...
Meghan O'Donnell
core
AI‐Driven Rational Design of Nanotherapeutics for Pancreatic Ductal Adenocarcinoma
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a formidable malignancy characterized by late diagnosis, high recurrence rates, and pronounced chemoresistance. While nanoparticle‐based drug delivery systems (NDDS) offer theoretical advantages over conventional therapies, their clinical translation in PDAC has been severely limited.
Seohyun Choo +4 more
wiley +1 more source

