Results 41 to 50 of about 223,907 (251)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Pharmacognostical study of Croton Crassifolius Geisel

open access: yesJournal of Holistic Integrative Pharmacy, 2023
Objectives: Croton Crassifolius Geisel of the genus Croton in the Euphorbia family is a widely distributed herb in South China. It has medicinal value for the treatment of a sore throat, soothing tendons, activating collateral, and treating rheumatoid ...
Zhuojun Huang, Wenfeng Weng, Shengguo Ji
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

An online identity authentication method for blood smear [PDF]

open access: yesJournal of Innovative Optical Health Sciences, 2016
Blood smear test is the basic method of blood cytology and is also a standard medical test that can help diagnose various conditions and diseases. Morphological examination is the gold standard to determine pathological changes in blood cell morphology ...
Xiaozhen Feng   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Classification of microscopic images of rock thin sections based on TLCA-ResNet34

open access: yesApplied Computing and Geosciences
Identifying microscopic images of rocks is a crucial method for rock identification, playing a vital role in geological exploration and mineral mining. To facilitate the quick classification and identification of rock thin sections under a microscope, a ...
Zhenyu Zhao   +6 more
doaj   +1 more source

CAR-T cells microscopic and phenotypic identification in the peripheral blood

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2022
CAR-T cells are a new possibility for care poor prognostic conditions. CAR-T cells injection lead to T chimeric cells circulation into the blood. Here is reported the cytomorphologic and immunophenotypic features of CAR-T cells in the peripheral blood.
LESESVE
doaj   +1 more source

Appendix C. Microscopic identification of LdNPV and Entomophaga maimaiga in larval cadavers.

open access: yes, 2016
Microscopic identification of LdNPV and Entomophaga maimaiga in larval ...
Ruth Plymale (2926305)   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy