Results 71 to 80 of about 3,055,647 (295)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

The Program Principle and Application of Microscopic Identification of Minerals

Yankuang ceshi, 2013
The microscopic identification of minerals can often be improved with the use of computer technology. An auxiliary analysis program for the microscopic identification of minerals based on Visual Basic tools is described in this paper.
WANG Lu-xin, FANG Qing-hua, WU Chao-dong
doaj  

Microscopic Identification of Babesia Spp in Sheep in Mosul City [PDF]

Basrah Journal of Veterinary Research
The Babesia is one of the most important parasites transmitted by hard ticks and is responsible for high infection and mortality rates in sheep herds in various countries of the world.
Eman . Suleiman, Baydaa Al-lahaibi
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The Econometric Analysis of Microscopic Simulation Models [PDF]

Microscopic simulation models are often evaluated based on visual inspection of the results.This paper presents formal econometric techniques to compare microscopic simulation (MS) models with real-life data.A related result is a methodology to compare ...
Melenberg, B., Li, Y., Donkers, A.C.D.
core   +2 more sources

The microscopic detection of animal proteins in feeds [PDF]

Biotechnologie, Agronomie, Société et Environnement, 2004
In the framework of the European Union funded research project STRATFEED for detection and identification of animal proteins in feeds, the microscopic method was optimized at several key steps and better documented. A check list was developed for uniform
Pinckaers V., Bosch J., Jorgenson J-S., Frick G., Zegers J., Vancutsem J., van Raamsdonk L. WD., Paradies-Severin I.   +7 more
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Deep Learning for Identification Malaria Diseases from Microscopic Image [PDF]

Iranian Journal of Electrical and Electronic Engineering
Malaria is a parasitic disease that causes significant morbidity and mortality worldwide. Early diagnosis and treatment are crucial for preventing complications and improving patient outcomes.
Edy Victor Haryanto S, Aimi Salihah Abdul Nasir, Mohd Yusoff Mashor, Bob Subhan Riza, Zeehaida Mohamed   +4 more
doaj