Results 101 to 110 of about 1,009,075 (346)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

DATA COLLECTION METHOD FOR PEDESTRIAN MOVEMENT VARIABLES

Civil Engineering Dimension, 2000
The need of tools for design and evaluation of pedestrian areas, subways stations, entrance hall, shopping mall, escape routes, stadium etc lead to the necessity of a pedestrian model.
Hajime Inamura, Yasushi Takeyama, Kardi Teknomo   +2 more
doaj  

Low-energy $^{6}$He scattering in a microscopic model

, 2016
A microscopic version of the Continuum Discretized Coupled Channel (CDCC) method is used to investigate $^{6}$He scattering on $^{27}$Al, $^{58}$Ni, $^{120}$Sn, and $^{208}$Pb at energies around the Coulomb barrier.
Descouvemont, P.
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Nuclear α-cluster structures from valence-space microscopic cluster model

Physics Letters B
Alpha clustering is an important dynamic in nuclear physics, with growing interest to its study in heavy nuclei in recent years. Theoretically, the microscopic cluster models taking nucleons as relevant degrees of freedom have been widely used to study α-
Zhen Wang, Dong Bai, Zhongzhou Ren
doaj   +1 more source

Microscopic modelling of doped manganites [PDF]

, 2004
Alexander Weiße, Holger Fehske
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Microscopic description of Landau-Lifshitz-Gilbert type equation based on the s-d model [PDF]

, 2006
Akimasa Sakuma
openalex   +1 more source

Combinatorial Level Densities from a Microscopic Relativistic Structure Model

, 2002
A new model for calculating nuclear level densities is investigated. The single-nucleon spectra are calculated in a relativistic mean-field model with energy-dependent effective mass, which yields a realistic density of single-particle states at the ...
A Ventura, Albrecht, Alhassid, Berger, Bethe, Blokhin, Bohr, Cerf, Chakrabarty, D Vretenar, De-Shalit, Demetriou, Donati, Grimes, Hilaire, Hillman, Ignatyuk, Iljinov, Jacquemin, Jaminon, Jaminon, Lalazissis, Langanke, Lu, Lunev, Melby, Mengoni, Mengoni, Morrissey, Mughabghab, Mustafa, Nakada, Nakada, Nikšić, Nikšić, Paar, R Pezer, Reinhard, Ring, Serot, Shlomo, Siem, Sunko, Sunko, Sunko, Sunko, Tondeur, Typel, Von Egidy, Vretenar, Williams, Williams, Zuker   +52 more
core   +2 more sources