Results 11 to 20 of about 10,280 (206)
BackgroundUtilizing the traditional centers of excellence approach to conduct clinical trials involving rare diseases remains challenging.
Springer, Jason Michael +6 more
doaj +1 more source
Antineutrophil cytoplasmic antibody associated vasculitis includes granulomatosis with polyangiitis, eosinophilic granulomatosis with polyangiitis (EGPA), and microscopic polyangiitis.
Lirong Lin +4 more
doaj +1 more source
Characterizing infection in anti-neutrophil cytoplasmic antibody-associated vasculitis:results from a longitudinal, matched-cohort data linkage study [PDF]
Objectives: Infection exerts a major burden in ANCA-associated vasculitis (AAV), however, its precise extent and nature remains unclear. In this national study we aimed to longitudinally quantify, characterize and contextualize infection risk in AAV ...
Amft, Nicole +11 more
core +6 more sources
The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Although extra‐glomerular involvement of microscopic polyangiitis is not regarded as a characteristic finding of the disease, tubulointerstitial nephritis should be considered as a new subclass of renal involvement.
Se Hee Kim +3 more
doaj +1 more source
Clinical features of kidney involvement in microscopic microscopic polyangiitis [PDF]
Aim. To evaluate clinical features and outcomes of renal involvement in patients with microscopic polyangiitis (MPA). Materials and methods: We enrolled 99 patients with MPA, diagnosed in accordance with the algorithm of the European Medicines Evaluation
E M Shchegoleva +3 more
doaj +1 more source
Temporal Arteritis and Vision Loss in Microscopic Polyangiitis: A Case Report and Literature Review
Microscopic polyangiitis (MPA) is an idiopathic autoimmune disease characterized by systemic vasculitis. While the lungs and kidneys are the major organs affected by MPA, it is known to involve multiple organ systems throughout the body.
Alexander G. Goglia +3 more
doaj +1 more source
Molecular targeted therapies for microscopic polyangiitis and granulomatosis with polyangiitis [PDF]
Clinical trials and observational studies have established cyclophosphamide (CY) or rituximab plus glucocorticoid (GC) as standard remission induction therapies in patients with microscopic polyangiitis (MPA) and granulomatosis with polyangiitis (GPA ...
Masayoshi Harigai +3 more
doaj +1 more source
ANCA Associated Mononeuritis Multiplex with Overlap in Vasculitic Syndromes [PDF]
Mononeuritis multiplex is a common manifestation of many illnesses which includes Hansen’s disease and certain types of systemic vasculitis. The Antineutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis (AAV) is a group of rare diseases which ...
Ravi Anadure +3 more
doaj +1 more source
The anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs) are a group of severe life-threatening autoimmune diseases, and one of the most important problems in practical rheumatology.
T. V. Beketova +2 more
doaj +1 more source

